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PLPP5 (phospholipid phosphatase 5)

Identity

Alias_namesPPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
Alias_symbol (synonym)HTPAP
DPPL1
Other alias
HGNC (Hugo) PLPP5
LocusID (NCBI) 84513
Atlas_Id 55473
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 38263132 and ends at 38269220 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADAM18 (8p11.22) / PLPP5 (8p11.23)PLPP5 (8p11.23) / RPL3 (22q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLPP5   25026
Cards
Entrez_Gene (NCBI)PLPP5  84513  phospholipid phosphatase 5
AliasesDPPL1; HTPAP; PPAPDC1B
GeneCards (Weizmann)PLPP5
Ensembl hg19 (Hinxton)ENSG00000147535 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147535 [Gene_View]  chr8:38263132-38269220 [Contig_View]  PLPP5 [Vega]
ICGC DataPortalENSG00000147535
TCGA cBioPortalPLPP5
AceView (NCBI)PLPP5
Genatlas (Paris)PLPP5
WikiGenes84513
SOURCE (Princeton)PLPP5
Genetics Home Reference (NIH)PLPP5
Genomic and cartography
GoldenPath hg38 (UCSC)PLPP5  -     chr8:38263132-38269220 -  8p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLPP5  -     8p11.23   [Description]    (hg19-Feb_2009)
EnsemblPLPP5 - 8p11.23 [CytoView hg19]  PLPP5 - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBIPLPP5 [Mapview hg19]  PLPP5 [Mapview hg38]
OMIM610626   
Gene and transcription
Genbank (Entrez)AA761242 AF212238 AK292118 BC033025 BC106014
RefSeq transcript (Entrez)NM_001102559 NM_001102560 NM_032483
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLPP5
Cluster EST : UnigeneHs.567619 [ NCBI ]
CGAP (NCI)Hs.567619
Alternative Splicing GalleryENSG00000147535
Gene ExpressionPLPP5 [ NCBI-GEO ]   PLPP5 [ EBI - ARRAY_EXPRESS ]   PLPP5 [ SEEK ]   PLPP5 [ MEM ]
Gene Expression Viewer (FireBrowse)PLPP5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84513
GTEX Portal (Tissue expression)PLPP5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NEB5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NEB5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NEB5
Splice isoforms : SwissVarQ8NEB5
Catalytic activity : Enzyme3.1.3.4 [ Enzyme-Expasy ]   3.1.3.43.1.3.4 [ IntEnz-EBI ]   3.1.3.4 [ BRENDA ]   3.1.3.4 [ KEGG ]   
PhosPhoSitePlusQ8NEB5
Domains : Interpro (EBI)P_Acid_Pase_2/haloperoxidase    PPAPDC1B   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)PLPP5
DMDM Disease mutations84513
Blocks (Seattle)PLPP5
SuperfamilyQ8NEB5
Human Protein AtlasENSG00000147535
Peptide AtlasQ8NEB5
HPRD13720
IPIIPI00941584   IPI00942514   IPI00973295   IPI00978975   IPI00856066   IPI00978374   IPI00976881   IPI00980347   
Protein Interaction databases
DIP (DOE-UCLA)Q8NEB5
IntAct (EBI)Q8NEB5
FunCoupENSG00000147535
BioGRIDPLPP5
STRING (EMBL)PLPP5
ZODIACPLPP5
Ontologies - Pathways
QuickGOQ8NEB5
Ontology : AmiGOcytoplasm  plasma membrane  integral component of plasma membrane  phospholipid metabolic process  signal transduction  phosphatidate phosphatase activity  phospholipid dephosphorylation  
Ontology : EGO-EBIcytoplasm  plasma membrane  integral component of plasma membrane  phospholipid metabolic process  signal transduction  phosphatidate phosphatase activity  phospholipid dephosphorylation  
NDEx NetworkPLPP5
Atlas of Cancer Signalling NetworkPLPP5
Wikipedia pathwaysPLPP5
Orthology - Evolution
OrthoDB84513
GeneTree (enSembl)ENSG00000147535
Phylogenetic Trees/Animal Genes : TreeFamPLPP5
HOVERGENQ8NEB5
HOGENOMQ8NEB5
Homologs : HomoloGenePLPP5
Homology/Alignments : Family Browser (UCSC)PLPP5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLPP5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLPP5
dbVarPLPP5
ClinVarPLPP5
1000_GenomesPLPP5 
Exome Variant ServerPLPP5
ExAC (Exome Aggregation Consortium)PLPP5 (select the gene name)
Genetic variants : HAPMAP84513
Genomic Variants (DGV)PLPP5 [DGVbeta]
DECIPHERPLPP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLPP5 
Mutations
ICGC Data PortalPLPP5 
TCGA Data PortalPLPP5 
Broad Tumor PortalPLPP5
OASIS PortalPLPP5 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPLPP5
BioMutasearch PLPP5
DgiDB (Drug Gene Interaction Database)PLPP5
DoCM (Curated mutations)PLPP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLPP5 (select a term)
intoGenPLPP5
Cancer3DPLPP5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610626   
Orphanet
MedgenPLPP5
Genetic Testing Registry PLPP5
NextProtQ8NEB5 [Medical]
TSGene84513
GENETestsPLPP5
Huge Navigator PLPP5 [HugePedia]
snp3D : Map Gene to Disease84513
BioCentury BCIQPLPP5
ClinGenPLPP5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84513
Chemical/Pharm GKB GenePA142671154
Clinical trialPLPP5
Miscellaneous
canSAR (ICR)PLPP5 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLPP5
EVEXPLPP5
GoPubMedPLPP5
iHOPPLPP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:31:42 CEST 2017

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