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PLPPR2 (phospholipid phosphatase related 2)

Identity

Alias_symbol (synonym)LPPR2
PRG-4
Other aliasPRG4
HGNC (Hugo) PLPPR2
LocusID (NCBI) 64748
Atlas_Id 77953
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 11355386 and ends at 11365698 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PLPPR2 (19p13.2) / COPS6 (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLPPR2   29566
Cards
Entrez_Gene (NCBI)PLPPR2  64748  phospholipid phosphatase related 2
AliasesLPPR2; PRG4
GeneCards (Weizmann)PLPPR2
Ensembl hg19 (Hinxton)ENSG00000105520 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105520 [Gene_View]  chr19:11355386-11365698 [Contig_View]  PLPPR2 [Vega]
ICGC DataPortalENSG00000105520
TCGA cBioPortalPLPPR2
AceView (NCBI)PLPPR2
Genatlas (Paris)PLPPR2
WikiGenes64748
SOURCE (Princeton)PLPPR2
Genetics Home Reference (NIH)PLPPR2
Genomic and cartography
GoldenPath hg38 (UCSC)PLPPR2  -     chr19:11355386-11365698 +  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLPPR2  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblPLPPR2 - 19p13.2 [CytoView hg19]  PLPPR2 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIPLPPR2 [Mapview hg19]  PLPPR2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK023117 AK094869 AK225482 AL353953 AY304516
RefSeq transcript (Entrez)NM_001170635 NM_022737
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLPPR2
Cluster EST : UnigeneHs.6846 [ NCBI ]
CGAP (NCI)Hs.6846
Alternative Splicing GalleryENSG00000105520
Gene ExpressionPLPPR2 [ NCBI-GEO ]   PLPPR2 [ EBI - ARRAY_EXPRESS ]   PLPPR2 [ SEEK ]   PLPPR2 [ MEM ]
Gene Expression Viewer (FireBrowse)PLPPR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64748
GTEX Portal (Tissue expression)PLPPR2
Human Protein AtlasENSG00000105520-PLPPR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GM1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GM1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GM1
Splice isoforms : SwissVarQ96GM1
Catalytic activity : Enzyme3.1.3.4 [ Enzyme-Expasy ]   3.1.3.43.1.3.4 [ IntEnz-EBI ]   3.1.3.4 [ BRENDA ]   3.1.3.4 [ KEGG ]   
PhosPhoSitePlusQ96GM1
Domains : Interpro (EBI)LPPR2    P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)PLPPR2
DMDM Disease mutations64748
Blocks (Seattle)PLPPR2
SuperfamilyQ96GM1
Human Protein Atlas [tissue]ENSG00000105520-PLPPR2 [tissue]
Peptide AtlasQ96GM1
HPRD17442
IPIIPI00396363   IPI00166272   
Protein Interaction databases
DIP (DOE-UCLA)Q96GM1
IntAct (EBI)Q96GM1
FunCoupENSG00000105520
BioGRIDPLPPR2
STRING (EMBL)PLPPR2
ZODIACPLPPR2
Ontologies - Pathways
QuickGOQ96GM1
Ontology : AmiGOintegral component of plasma membrane  phospholipid metabolic process  signal transduction  phosphatidate phosphatase activity  lipid phosphatase activity  phospholipid dephosphorylation  
Ontology : EGO-EBIintegral component of plasma membrane  phospholipid metabolic process  signal transduction  phosphatidate phosphatase activity  lipid phosphatase activity  phospholipid dephosphorylation  
NDEx NetworkPLPPR2
Atlas of Cancer Signalling NetworkPLPPR2
Wikipedia pathwaysPLPPR2
Orthology - Evolution
OrthoDB64748
GeneTree (enSembl)ENSG00000105520
Phylogenetic Trees/Animal Genes : TreeFamPLPPR2
HOVERGENQ96GM1
HOGENOMQ96GM1
Homologs : HomoloGenePLPPR2
Homology/Alignments : Family Browser (UCSC)PLPPR2
Gene fusions - Rearrangements
Fusion: Tumor Portal PLPPR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLPPR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLPPR2
dbVarPLPPR2
ClinVarPLPPR2
1000_GenomesPLPPR2 
Exome Variant ServerPLPPR2
ExAC (Exome Aggregation Consortium)ENSG00000105520
GNOMAD BrowserENSG00000105520
Genetic variants : HAPMAP64748
Genomic Variants (DGV)PLPPR2 [DGVbeta]
DECIPHERPLPPR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLPPR2 
Mutations
ICGC Data PortalPLPPR2 
TCGA Data PortalPLPPR2 
Broad Tumor PortalPLPPR2
OASIS PortalPLPPR2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPLPPR2
BioMutasearch PLPPR2
DgiDB (Drug Gene Interaction Database)PLPPR2
DoCM (Curated mutations)PLPPR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLPPR2 (select a term)
intoGenPLPPR2
Cancer3DPLPPR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPLPPR2
Genetic Testing Registry PLPPR2
NextProtQ96GM1 [Medical]
TSGene64748
GENETestsPLPPR2
Target ValidationPLPPR2
Huge Navigator PLPPR2 [HugePedia]
snp3D : Map Gene to Disease64748
BioCentury BCIQPLPPR2
ClinGenPLPPR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64748
Clinical trialPLPPR2
Miscellaneous
canSAR (ICR)PLPPR2 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLPPR2
EVEXPLPPR2
GoPubMedPLPPR2
iHOPPLPPR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:22:53 CET 2017

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