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PLPPR5 (phospholipid phosphatase related 5)

Identity

Alias_symbol (synonym)PAP2D
PAP2
LPPR5
PRG5
Other alias
HGNC (Hugo) PLPPR5
LocusID (NCBI) 163404
Atlas_Id 77956
Location 1p21.3  [Link to chromosome band 1p21]
Location_base_pair Starts at 98890245 and ends at 99004893 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PLPPR5 (1p21.3) / FGF13 (Xq26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLPPR5   31703
Cards
Entrez_Gene (NCBI)PLPPR5  163404  phospholipid phosphatase related 5
AliasesLPPR5; PAP2; PAP2D; PRG5
GeneCards (Weizmann)PLPPR5
Ensembl hg19 (Hinxton)ENSG00000117598 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117598 [Gene_View]  chr1:98890245-99004893 [Contig_View]  PLPPR5 [Vega]
ICGC DataPortalENSG00000117598
TCGA cBioPortalPLPPR5
AceView (NCBI)PLPPR5
Genatlas (Paris)PLPPR5
WikiGenes163404
SOURCE (Princeton)PLPPR5
Genetics Home Reference (NIH)PLPPR5
Genomic and cartography
GoldenPath hg38 (UCSC)PLPPR5  -     chr1:98890245-99004893 -  1p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLPPR5  -     1p21.3   [Description]    (hg19-Feb_2009)
EnsemblPLPPR5 - 1p21.3 [CytoView hg19]  PLPPR5 - 1p21.3 [CytoView hg38]
Mapping of homologs : NCBIPLPPR5 [Mapview hg19]  PLPPR5 [Mapview hg38]
OMIM617287   
Gene and transcription
Genbank (Entrez)AF131783 AK295688 AY574039 AY634620 BC040174
RefSeq transcript (Entrez)NM_001010861 NM_001037317
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLPPR5
Cluster EST : UnigeneHs.483948 [ NCBI ]
CGAP (NCI)Hs.483948
Alternative Splicing GalleryENSG00000117598
Gene ExpressionPLPPR5 [ NCBI-GEO ]   PLPPR5 [ EBI - ARRAY_EXPRESS ]   PLPPR5 [ SEEK ]   PLPPR5 [ MEM ]
Gene Expression Viewer (FireBrowse)PLPPR5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)163404
GTEX Portal (Tissue expression)PLPPR5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ32ZL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ32ZL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ32ZL2
Splice isoforms : SwissVarQ32ZL2
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusQ32ZL2
Domains : Interpro (EBI)LPPR5    P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)PLPPR5
DMDM Disease mutations163404
Blocks (Seattle)PLPPR5
SuperfamilyQ32ZL2
Human Protein AtlasENSG00000117598
Peptide AtlasQ32ZL2
HPRD12966
IPIIPI00656084   IPI00402043   
Protein Interaction databases
DIP (DOE-UCLA)Q32ZL2
IntAct (EBI)Q32ZL2
FunCoupENSG00000117598
BioGRIDPLPPR5
STRING (EMBL)PLPPR5
ZODIACPLPPR5
Ontologies - Pathways
QuickGOQ32ZL2
Ontology : AmiGOplasma membrane  integral component of plasma membrane  phospholipid metabolic process  signal transduction  phosphatidate phosphatase activity  positive regulation of neuron projection development  lipid phosphatase activity  phospholipid dephosphorylation  positive regulation of filopodium assembly  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  phospholipid metabolic process  signal transduction  phosphatidate phosphatase activity  positive regulation of neuron projection development  lipid phosphatase activity  phospholipid dephosphorylation  positive regulation of filopodium assembly  
NDEx NetworkPLPPR5
Atlas of Cancer Signalling NetworkPLPPR5
Wikipedia pathwaysPLPPR5
Orthology - Evolution
OrthoDB163404
GeneTree (enSembl)ENSG00000117598
Phylogenetic Trees/Animal Genes : TreeFamPLPPR5
HOVERGENQ32ZL2
HOGENOMQ32ZL2
Homologs : HomoloGenePLPPR5
Homology/Alignments : Family Browser (UCSC)PLPPR5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLPPR5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLPPR5
dbVarPLPPR5
ClinVarPLPPR5
1000_GenomesPLPPR5 
Exome Variant ServerPLPPR5
ExAC (Exome Aggregation Consortium)PLPPR5 (select the gene name)
Genetic variants : HAPMAP163404
Genomic Variants (DGV)PLPPR5 [DGVbeta]
DECIPHERPLPPR5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLPPR5 
Mutations
ICGC Data PortalPLPPR5 
TCGA Data PortalPLPPR5 
Broad Tumor PortalPLPPR5
OASIS PortalPLPPR5 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPLPPR5
BioMutasearch PLPPR5
DgiDB (Drug Gene Interaction Database)PLPPR5
DoCM (Curated mutations)PLPPR5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLPPR5 (select a term)
intoGenPLPPR5
Cancer3DPLPPR5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617287   
Orphanet
MedgenPLPPR5
Genetic Testing Registry PLPPR5
NextProtQ32ZL2 [Medical]
TSGene163404
GENETestsPLPPR5
Target ValidationPLPPR5
Huge Navigator PLPPR5 [HugePedia]
snp3D : Map Gene to Disease163404
BioCentury BCIQPLPPR5
ClinGenPLPPR5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD163404
Clinical trialPLPPR5
Miscellaneous
canSAR (ICR)PLPPR5 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLPPR5
EVEXPLPPR5
GoPubMedPLPPR5
iHOPPLPPR5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:41 CEST 2017

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