Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PLSCR4 (phospholipid scramblase 4)

Identity

Other aliasTRA1
HGNC (Hugo) PLSCR4
LocusID (NCBI) 57088
Atlas_Id 72008
Location 3q24  [Link to chromosome band 3q24]
Location_base_pair Starts at 146192336 and ends at 146251179 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PLOD2 (3q24) / PLSCR4 (3q24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLSCR4   16497
Cards
Entrez_Gene (NCBI)PLSCR4  57088  phospholipid scramblase 4
AliasesTRA1
GeneCards (Weizmann)PLSCR4
Ensembl hg19 (Hinxton)ENSG00000114698 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114698 [Gene_View]  chr3:146192336-146251179 [Contig_View]  PLSCR4 [Vega]
ICGC DataPortalENSG00000114698
TCGA cBioPortalPLSCR4
AceView (NCBI)PLSCR4
Genatlas (Paris)PLSCR4
WikiGenes57088
SOURCE (Princeton)PLSCR4
Genetics Home Reference (NIH)PLSCR4
Genomic and cartography
GoldenPath hg38 (UCSC)PLSCR4  -     chr3:146192336-146251179 -  3q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLSCR4  -     3q24   [Description]    (hg19-Feb_2009)
EnsemblPLSCR4 - 3q24 [CytoView hg19]  PLSCR4 - 3q24 [CytoView hg38]
Mapping of homologs : NCBIPLSCR4 [Mapview hg19]  PLSCR4 [Mapview hg38]
OMIM607612   
Gene and transcription
Genbank (Entrez)AF087887 AF199023 AK128442 AK290214 AK292815
RefSeq transcript (Entrez)NM_001128304 NM_001128305 NM_001128306 NM_001177304 NM_020353
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLSCR4
Cluster EST : UnigeneHs.477869 [ NCBI ]
CGAP (NCI)Hs.477869
Alternative Splicing GalleryENSG00000114698
Gene ExpressionPLSCR4 [ NCBI-GEO ]   PLSCR4 [ EBI - ARRAY_EXPRESS ]   PLSCR4 [ SEEK ]   PLSCR4 [ MEM ]
Gene Expression Viewer (FireBrowse)PLSCR4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57088
GTEX Portal (Tissue expression)PLSCR4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRQ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRQ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRQ2
Splice isoforms : SwissVarQ9NRQ2
PhosPhoSitePlusQ9NRQ2
Domains : Interpro (EBI)Scramblase   
Domain families : Pfam (Sanger)Scramblase (PF03803)   
Domain families : Pfam (NCBI)pfam03803   
Conserved Domain (NCBI)PLSCR4
DMDM Disease mutations57088
Blocks (Seattle)PLSCR4
PDB (SRS)3Q5U   
PDB (PDBSum)3Q5U   
PDB (IMB)3Q5U   
PDB (RSDB)3Q5U   
Structural Biology KnowledgeBase3Q5U   
SCOP (Structural Classification of Proteins)3Q5U   
CATH (Classification of proteins structures)3Q5U   
SuperfamilyQ9NRQ2
Human Protein AtlasENSG00000114698
Peptide AtlasQ9NRQ2
HPRD07401
IPIIPI00016776   IPI00794048   IPI00945326   IPI00946225   IPI00946041   IPI00796880   IPI00945242   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRQ2
IntAct (EBI)Q9NRQ2
FunCoupENSG00000114698
BioGRIDPLSCR4
STRING (EMBL)PLSCR4
ZODIACPLSCR4
Ontologies - Pathways
QuickGOQ9NRQ2
Ontology : AmiGOcalcium ion binding  protein binding  plasma membrane  integral component of membrane  phospholipid scrambling  SH3 domain binding  phospholipid scramblase activity  phospholipid scramblase activity  enzyme binding  CD4 receptor binding  extracellular exosome  cellular response to lipopolysaccharide  
Ontology : EGO-EBIcalcium ion binding  protein binding  plasma membrane  integral component of membrane  phospholipid scrambling  SH3 domain binding  phospholipid scramblase activity  phospholipid scramblase activity  enzyme binding  CD4 receptor binding  extracellular exosome  cellular response to lipopolysaccharide  
NDEx NetworkPLSCR4
Atlas of Cancer Signalling NetworkPLSCR4
Wikipedia pathwaysPLSCR4
Orthology - Evolution
OrthoDB57088
GeneTree (enSembl)ENSG00000114698
Phylogenetic Trees/Animal Genes : TreeFamPLSCR4
HOVERGENQ9NRQ2
HOGENOMQ9NRQ2
Homologs : HomoloGenePLSCR4
Homology/Alignments : Family Browser (UCSC)PLSCR4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLSCR4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLSCR4
dbVarPLSCR4
ClinVarPLSCR4
1000_GenomesPLSCR4 
Exome Variant ServerPLSCR4
ExAC (Exome Aggregation Consortium)PLSCR4 (select the gene name)
Genetic variants : HAPMAP57088
Genomic Variants (DGV)PLSCR4 [DGVbeta]
DECIPHERPLSCR4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLSCR4 
Mutations
ICGC Data PortalPLSCR4 
TCGA Data PortalPLSCR4 
Broad Tumor PortalPLSCR4
OASIS PortalPLSCR4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLSCR4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLSCR4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLSCR4
DgiDB (Drug Gene Interaction Database)PLSCR4
DoCM (Curated mutations)PLSCR4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLSCR4 (select a term)
intoGenPLSCR4
Cancer3DPLSCR4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607612   
Orphanet
MedgenPLSCR4
Genetic Testing Registry PLSCR4
NextProtQ9NRQ2 [Medical]
TSGene57088
GENETestsPLSCR4
Target ValidationPLSCR4
Huge Navigator PLSCR4 [HugePedia]
snp3D : Map Gene to Disease57088
BioCentury BCIQPLSCR4
ClinGenPLSCR4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57088
Chemical/Pharm GKB GenePA33422
Clinical trialPLSCR4
Miscellaneous
canSAR (ICR)PLSCR4 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLSCR4
EVEXPLSCR4
GoPubMedPLSCR4
iHOPPLSCR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:36:43 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.