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PLTP (phospholipid transfer protein)

Identity

Alias_symbol (synonym)BPIFE
Other aliasHDLCQ9
HGNC (Hugo) PLTP
LocusID (NCBI) 5360
Atlas_Id 51749
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 45898620 and ends at 45912364 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLTP   9093
Cards
Entrez_Gene (NCBI)PLTP  5360  phospholipid transfer protein
AliasesBPIFE; HDLCQ9
GeneCards (Weizmann)PLTP
Ensembl hg19 (Hinxton)ENSG00000100979 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100979 [Gene_View]  ENSG00000100979 [Sequence]  chr20:45898620-45912364 [Contig_View]  PLTP [Vega]
ICGC DataPortalENSG00000100979
TCGA cBioPortalPLTP
AceView (NCBI)PLTP
Genatlas (Paris)PLTP
WikiGenes5360
SOURCE (Princeton)PLTP
Genetics Home Reference (NIH)PLTP
Genomic and cartography
GoldenPath hg38 (UCSC)PLTP  -     chr20:45898620-45912364 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLTP  -     20q13.12   [Description]    (hg19-Feb_2009)
GoldenPathPLTP - 20q13.12 [CytoView hg19]  PLTP - 20q13.12 [CytoView hg38]
Genome Data Viewer NCBIPLTP [Mapview hg19]  
OMIM172425   
Gene and transcription
Genbank (Entrez)AB076694 AF052157 AK092397 AK092523 AK097009
RefSeq transcript (Entrez)NM_001242920 NM_001242921 NM_006227 NM_182676
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLTP
Alternative Splicing GalleryENSG00000100979
Gene ExpressionPLTP [ NCBI-GEO ]   PLTP [ EBI - ARRAY_EXPRESS ]   PLTP [ SEEK ]   PLTP [ MEM ]
Gene Expression Viewer (FireBrowse)PLTP [ Firebrowse - Broad ]
GenevisibleExpression of PLTP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5360
GTEX Portal (Tissue expression)PLTP
Human Protein AtlasENSG00000100979-PLTP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55058   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55058  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55058
Splice isoforms : SwissVarP55058
PhosPhoSitePlusP55058
Domaine pattern : Prosite (Expaxy)LBP_BPI_CETP (PS00400)   
Domains : Interpro (EBI)Bactericidal_perm-incr_a/b_dom    BPI/LBP    BPI/LBP/Plunc    Lipid-bd_serum_glycop_C    Lipid-bd_serum_glycop_CS    Lipid-bd_serum_glycop_N    PLTP   
Domain families : Pfam (Sanger)LBP_BPI_CETP (PF01273)    LBP_BPI_CETP_C (PF02886)   
Domain families : Pfam (NCBI)pfam01273    pfam02886   
Domain families : Smart (EMBL)BPI1 (SM00328)  BPI2 (SM00329)  
Conserved Domain (NCBI)PLTP
DMDM Disease mutations5360
SuperfamilyP55058
Human Protein Atlas [tissue]ENSG00000100979-PLTP [tissue]
Peptide AtlasP55058
HPRD01399
IPIIPI01010596   IPI00217778   IPI00643034   IPI00022733   IPI00909702   
Protein Interaction databases
DIP (DOE-UCLA)P55058
IntAct (EBI)P55058
FunCoupENSG00000100979
BioGRIDPLTP
STRING (EMBL)PLTP
ZODIACPLTP
Ontologies - Pathways
QuickGOP55058
Ontology : AmiGOextracellular region  extracellular space  extracellular space  nucleus  lipid metabolic process  lipid transport  high-density lipoprotein particle binding  phosphatidylethanolamine binding  phosphatidylethanolamine binding  phosphatidylcholine transporter activity  phosphatidylinositol transporter activity  vitamin E biosynthetic process  positive regulation of cholesterol efflux  phospholipid transport  phospholipid transport  sterol transport  diacylglycerol binding  diacylglycerol binding  low-density lipoprotein particle binding  flagellated sperm motility  phosphatidylcholine binding  phosphatidylcholine binding  very-low-density lipoprotein particle binding  high-density lipoprotein particle  high-density lipoprotein particle remodeling  high-density lipoprotein particle remodeling  ceramide transport  ceramide transport  glycolipid transport  phosphatidic acid binding  phosphatidic acid binding  ceramide binding  ceramide binding  intermembrane lipid transfer  intermembrane phospholipid transfer activity  intermembrane phospholipid transfer activity  intermembrane ceramide transfer activity  intermembrane phosphotidylcholine transfer activity  intermembrane cholesterol transfer activity  phosphatidylglycerol binding  phosphatidylglycerol binding  phosphatidylethanolamine transporter activity  phosphatidylethanolamine transporter activity  phosphatidic acid transporter activity  phosphatidic acid transporter activity  
Ontology : EGO-EBIextracellular region  extracellular space  extracellular space  nucleus  lipid metabolic process  lipid transport  high-density lipoprotein particle binding  phosphatidylethanolamine binding  phosphatidylethanolamine binding  phosphatidylcholine transporter activity  phosphatidylinositol transporter activity  vitamin E biosynthetic process  positive regulation of cholesterol efflux  phospholipid transport  phospholipid transport  sterol transport  diacylglycerol binding  diacylglycerol binding  low-density lipoprotein particle binding  flagellated sperm motility  phosphatidylcholine binding  phosphatidylcholine binding  very-low-density lipoprotein particle binding  high-density lipoprotein particle  high-density lipoprotein particle remodeling  high-density lipoprotein particle remodeling  ceramide transport  ceramide transport  glycolipid transport  phosphatidic acid binding  phosphatidic acid binding  ceramide binding  ceramide binding  intermembrane lipid transfer  intermembrane phospholipid transfer activity  intermembrane phospholipid transfer activity  intermembrane ceramide transfer activity  intermembrane phosphotidylcholine transfer activity  intermembrane cholesterol transfer activity  phosphatidylglycerol binding  phosphatidylglycerol binding  phosphatidylethanolamine transporter activity  phosphatidylethanolamine transporter activity  phosphatidic acid transporter activity  phosphatidic acid transporter activity  
Pathways : KEGGPPAR signaling pathway   
NDEx NetworkPLTP
Atlas of Cancer Signalling NetworkPLTP
Wikipedia pathwaysPLTP
Orthology - Evolution
OrthoDB5360
GeneTree (enSembl)ENSG00000100979
Phylogenetic Trees/Animal Genes : TreeFamPLTP
HOGENOMP55058
Homologs : HomoloGenePLTP
Homology/Alignments : Family Browser (UCSC)PLTP
Gene fusions - Rearrangements
Fusion : QuiverPLTP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLTP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLTP
dbVarPLTP
ClinVarPLTP
1000_GenomesPLTP 
Exome Variant ServerPLTP
GNOMAD BrowserENSG00000100979
Varsome BrowserPLTP
Genetic variants : HAPMAP5360
Genomic Variants (DGV)PLTP [DGVbeta]
DECIPHERPLTP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLTP 
Mutations
ICGC Data PortalPLTP 
TCGA Data PortalPLTP 
Broad Tumor PortalPLTP
OASIS PortalPLTP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLTP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPLTP
Mutations and Diseases : HGMDPLTP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect PLTP
DgiDB (Drug Gene Interaction Database)PLTP
DoCM (Curated mutations)PLTP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLTP (select a term)
intoGenPLTP
Cancer3DPLTP (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM172425   
Orphanet
DisGeNETPLTP
MedgenPLTP
Genetic Testing Registry PLTP
NextProtP55058 [Medical]
TSGene5360
GENETestsPLTP
Open Targets GeneticsENSG00000100979  [validation]
snp3D : Map Gene to Disease5360
BioCentury BCIQPLTP
ClinGenPLTP
Clinical trials, drugs, therapy
Protein Interactions : CTD5360
Pharm GKB GenePA273
Pharm GKB PathwaysPA2031   
Clinical trialPLTP
Miscellaneous
canSAR (ICR)PLTP (select the gene name)
HarmonizomePLTP
DataMed IndexPLTP
Probes
Litterature
PubMed140 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLTP
EVEXPLTP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Jul 11 20:05:37 CEST 2020

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