PLXNB2 (plexin B2)

2006-10-01  

Identity

HGNC
LOCATION
22q13.33
LOCUSID
ALIAS
MM1,Nbla00445,PLEXB2,dJ402G11.3
FUSION GENES

Other Information

Locus ID:

NCBI: 23654
MIM: 604293
HGNC: 9104
Ensembl: ENSG00000196576

Variants:

dbSNP: 23654
ClinVar: 23654
TCGA: ENSG00000196576
COSMIC: PLXNB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196576ENST00000359337O15031
ENSG00000196576ENST00000411680A6QRG9
ENSG00000196576ENST00000425954A6QRH1
ENSG00000196576ENST00000427829H0Y6J7
ENSG00000196576ENST00000432455E2PU09
ENSG00000196576ENST00000434732H0Y7X5
ENSG00000196576ENST00000449103O15031
ENSG00000196576ENST00000610984A0A087X000
ENSG00000196576ENST00000614805A0A087WU36

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
121834582002Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.79
125335442003Functional regulation of semaphorin receptors by proprotein convertases.23
257626462015Plexin-B2 promotes invasive growth of malignant glioma.16
241581122013Experimental validation of 5 in-silico predicted glioma biomarkers.14
262753422015CD100 and plexins B2 and B1 mediate monocyte-endothelial cell adhesion and might take part in atherogenesis.11
291000742017Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin.10
260352162015Reduced expression of semaphorin 4D and plexin-B in breast cancer is associated with poorer prognosis and the potential linkage with oestrogen receptor.9
252370062015Endometrial apical glycoproteomic analysis reveals roles for cadherin 6, desmoglein-2 and plexin b2 in epithelial integrity.8
289278922018CD100-Plexin-B2 Promotes the Inflammation in Psoriasis by Activating NF-κB and the Inflammasome in Keratinocytes.7
295559782018Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential.6

Citation

Dessen P

PLXNB2 (plexin B2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/46040/plxnb2