Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PLXNB2 (plexin B2)

Identity

Other namesMM1
Nbla00445
PLEXB2
dJ402G11.3
HGNC (Hugo) PLXNB2
LocusID (NCBI) 23654
Location 22q13.33
Location_base_pair Starts at 50713408 and ends at 50746001 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PLXNB2   9104
Entrez_Gene (NCBI)PLXNB2  23654  plexin B2
Cards
GeneCards (Weizmann)PLXNB2
Ensembl (Hinxton)ENSG00000196576 [Gene_View]  chr22:50713408-50746001 [Contig_View]  PLXNB2 [Vega]
AceView (NCBI)PLXNB2
Genatlas (Paris)PLXNB2
SOURCE (Stanford)NM_012401
Genomic and cartography
GoldenPath (UCSC)PLXNB2  -  22q13.33   chr22:50713408-50746001 -  22q13.33   [Description]    (hg19-Feb_2009)
EnsemblPLXNB2 - 22q13.33 [CytoView]
Mapping of homologs : NCBIPLXNB2 [Mapview]
OMIM604293   
Gene and transcription
Genbank (Entrez)AB002313 AB075511 AK025415 AK025701 AK056543
RefSeq transcript (SRS)NM_012401
RefSeq transcript (Entrez)NM_012401
RefSeq genomic (SRS)AC_000154 NC_000022 NC_018933 NT_011526 NW_001838755 NW_004078112
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011526 NW_001838755 NW_004078112
Consensus coding sequences : CCDS (NCBI)PLXNB2
Cluster EST : UnigeneHs.736016 [ SRS ] Hs.736016 [ NCBI ]
CGAP (NCI)Hs.736016
Alternative Splicing : Fast-db (Paris)GSHG0020516
Alternative Splicing GalleryENSG00000196576
Gene ExpressionPLXNB2 [ NCBI-GEO ]   PLXNB2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15031 (SRS) O15031 (Uniprot)
NextProtO15031
With graphics : InterProO15031
Splice isoforms : SwissVarO15031(Swissvar)
Domaine pattern : Prosite (SRS)SEMA (PS51004)   
Domaine pattern : Prosite (Expaxy)SEMA (PS51004)   
Domains : Interpro (SRS)Ig-like_fold    Ig_E-set    IPT_TIG_rcpt    Plexin-like    Plexin-like_fold    Plexin_cytoplasmic_RasGAP_dom    Plexin_repeat    RasGAP    Rho_GTPase_activation_prot    Semaphorin/CD100_Ag    WD40/YVTN_repeat-like_dom   
Domains : Interpro (EBI)Ig-like_fold    Ig_E-set    IPT_TIG_rcpt    Plexin-like    Plexin-like_fold    Plexin_cytoplasmic_RasGAP_dom    Plexin_repeat    RasGAP    Rho_GTPase_activation_prot    Semaphorin/CD100_Ag    WD40/YVTN_repeat-like_dom   
Related proteins : CluSTrO15031
Domain families : Pfam (SRS)Plexin_cytopl (PF08337)    PSI (PF01437)    Sema (PF01403)    TIG (PF01833)   
Domain families : Pfam (Sanger)Plexin_cytopl (PF08337)    PSI (PF01437)    Sema (PF01403)    TIG (PF01833)   
Domain families : Pfam (NCBI)pfam08337    pfam01437    pfam01403    pfam01833   
Domain families : Smart (EMBL)IPT (SM00429)  PSI (SM00423)  Sema (SM00630)  
DMDM23654
Blocks (Seattle)O15031
PDB (SRS)4E71   
PDB (PDBSum)4E71   
PDB (IMB)4E71   
PDB (RSDB)4E71   
Human Protein AtlasENSG00000196576
HPRD05050
IPIIPI00853369   IPI00816626   IPI00383422   IPI00852623   IPI00941351   IPI00852734   IPI00852803   IPI00852891   
Protein Interaction databases
DIP (DOE-UCLA)O15031
IntAct (EBI)O15031
FunCoupENSG00000196576
REACTOMEPLXNB2
Protein Interaction Database23654
BioGRIDPLXNB2
InParanoidO15031
Interologous Interaction database O15031
IntegromeDBPLXNB2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PLXNB2
SNP (GeneSNP Utah)PLXNB2
SNP : HGBasePLXNB2
Genetic variants : HAPMAPPLXNB2
Somatic Mutations in Cancer : COSMICPLXNB2 
CONAN: Copy Number AnalysisPLXNB2 
Mutations and Diseases : HGMDPLXNB2
OMIM604293   
GENETests604293   
Disease Genetic AssociationPLXNB2
Huge Navigator PLXNB2 [HugePedia]  PLXNB2 [HugeCancerGEM]
Genomic VariantsPLXNB2  PLXNB2 [DGVbeta]
snp3D : Map Gene to Disease23654
General knowledge
Homologs : HomoloGenePLXNB2
Homology/Alignments : Family Browser (UCSC)PLXNB2
Phylogenetic Trees/Animal Genes : TreeFamPLXNB2
Chemical/Protein Interactions : CTD23654
Chemical/Pharm GKB GenePA33430
Clinical trialPLXNB2
Cancer Resource (Charite)ENSG00000196576
Ontology : AmiGOneural tube closure  regulation of protein phosphorylation  GTPase activator activity  protein binding  intracellular  integral to plasma membrane  neuroblast proliferation  brain development  regulation of cell shape  semaphorin receptor activity  regulation of Rho GTPase activity  positive regulation of axonogenesis  semaphorin-plexin signaling pathway  regulation of neuron migration  
Ontology : EGO-EBIneural tube closure  regulation of protein phosphorylation  GTPase activator activity  protein binding  intracellular  integral to plasma membrane  neuroblast proliferation  brain development  regulation of cell shape  semaphorin receptor activity  regulation of Rho GTPase activity  positive regulation of axonogenesis  semaphorin-plexin signaling pathway  regulation of neuron migration  
Pathways : KEGGAxon guidance
Other databases
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
PubGenePLXNB2
iHOPPLXNB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:26:03 CEST 2013
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