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PMEPA1 (prostate transmembrane protein, androgen induced 1)

Identity

Alias_namesTMEPAI
transmembrane
Alias_symbol (synonym)STAG1
Other alias
HGNC (Hugo) PMEPA1
LocusID (NCBI) 56937
Atlas_Id 42589
Location 20q13.31  [Link to chromosome band 20q13]
Location_base_pair Starts at 57648392 and ends at 57690624 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARID3A (19p13.3) / PMEPA1 (20q13.31)PMEPA1 (20q13.31) / ATF6 (1q23.3)PMEPA1 (20q13.31) / EMILIN3 (20q12)
PMEPA1 (20q13.31) / PIGP (21q22.13)PMEPA1 (20q13.31) / PMEPA1 (20q13.31)PMEPA1 (20q13.31) / PTGIS (20q13.13)
PMEPA1 (20q13.31) / RALY (20q11.22)RPN2 (20q11.23) / PMEPA1 (20q13.31)SLC35B1 (17q21.33) / PMEPA1 (20q13.31)
ARID3A 19p13.3 / PMEPA1 20q13.31PMEPA1 20q13.31 / EMILIN3 20q12PMEPA1 20q13.31 / PIGP 21q22.13
PMEPA1 20q13.31 / PTGIS 20q13.13PMEPA1 20q13.31 / RALY 20q11.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PMEPA1   14107
Cards
Entrez_Gene (NCBI)PMEPA1  56937  prostate transmembrane protein, androgen induced 1
AliasesSTAG1; TMEPAI
GeneCards (Weizmann)PMEPA1
Ensembl hg19 (Hinxton)ENSG00000124225 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124225 [Gene_View]  chr20:57648392-57690624 [Contig_View]  PMEPA1 [Vega]
ICGC DataPortalENSG00000124225
TCGA cBioPortalPMEPA1
AceView (NCBI)PMEPA1
Genatlas (Paris)PMEPA1
WikiGenes56937
SOURCE (Princeton)PMEPA1
Genetics Home Reference (NIH)PMEPA1
Genomic and cartography
GoldenPath hg38 (UCSC)PMEPA1  -     chr20:57648392-57690624 -  20q13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PMEPA1  -     20q13.31   [Description]    (hg19-Feb_2009)
EnsemblPMEPA1 - 20q13.31 [CytoView hg19]  PMEPA1 - 20q13.31 [CytoView hg38]
Mapping of homologs : NCBIPMEPA1 [Mapview hg19]  PMEPA1 [Mapview hg38]
OMIM606564   
Gene and transcription
Genbank (Entrez)AF224278 AF305616 AJ308020 AJ308021 AK024618
RefSeq transcript (Entrez)NM_001255976 NM_020182 NM_199169 NM_199170 NM_199171
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PMEPA1
Cluster EST : UnigeneHs.517155 [ NCBI ]
CGAP (NCI)Hs.517155
Alternative Splicing GalleryENSG00000124225
Gene ExpressionPMEPA1 [ NCBI-GEO ]   PMEPA1 [ EBI - ARRAY_EXPRESS ]   PMEPA1 [ SEEK ]   PMEPA1 [ MEM ]
Gene Expression Viewer (FireBrowse)PMEPA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56937
GTEX Portal (Tissue expression)PMEPA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969W9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969W9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969W9
Splice isoforms : SwissVarQ969W9
PhosPhoSitePlusQ969W9
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PMEPA1
DMDM Disease mutations56937
Blocks (Seattle)PMEPA1
SuperfamilyQ969W9
Human Protein AtlasENSG00000124225
Peptide AtlasQ969W9
HPRD09415
IPIIPI00056521   IPI00183679   IPI00790514   IPI00788664   IPI00396293   
Protein Interaction databases
DIP (DOE-UCLA)Q969W9
IntAct (EBI)Q969W9
FunCoupENSG00000124225
BioGRIDPMEPA1
STRING (EMBL)PMEPA1
ZODIACPMEPA1
Ontologies - Pathways
QuickGOQ969W9
Ontology : AmiGOGolgi membrane  protein binding  plasma membrane  endosome membrane  negative regulation of SMAD protein complex assembly  integral component of membrane  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  androgen receptor signaling pathway  early endosome membrane  early endosome membrane  intracellular membrane-bounded organelle  WW domain binding  negative regulation of pathway-restricted SMAD protein phosphorylation  negative regulation of pathway-restricted SMAD protein phosphorylation  R-SMAD binding  
Ontology : EGO-EBIGolgi membrane  protein binding  plasma membrane  endosome membrane  negative regulation of SMAD protein complex assembly  integral component of membrane  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  androgen receptor signaling pathway  early endosome membrane  early endosome membrane  intracellular membrane-bounded organelle  WW domain binding  negative regulation of pathway-restricted SMAD protein phosphorylation  negative regulation of pathway-restricted SMAD protein phosphorylation  R-SMAD binding  
NDEx NetworkPMEPA1
Atlas of Cancer Signalling NetworkPMEPA1
Wikipedia pathwaysPMEPA1
Orthology - Evolution
OrthoDB56937
GeneTree (enSembl)ENSG00000124225
Phylogenetic Trees/Animal Genes : TreeFamPMEPA1
HOVERGENQ969W9
HOGENOMQ969W9
Homologs : HomoloGenePMEPA1
Homology/Alignments : Family Browser (UCSC)PMEPA1
Gene fusions - Rearrangements
Fusion : MitelmanARID3A/PMEPA1 [19p13.3/20q13.31]  [t(19;20)(p13;q13)]  
Fusion : MitelmanPMEPA1/EMILIN3 [20q13.31/20q12]  [t(20;20)(q12;q13)]  
Fusion : MitelmanPMEPA1/PIGP [20q13.31/21q22.13]  [t(20;21)(q13;q22)]  
Fusion : MitelmanPMEPA1/PTGIS [20q13.31/20q13.13]  [t(20;20)(q13;q13)]  
Fusion : MitelmanPMEPA1/RALY [20q13.31/20q11.22]  [t(20;20)(q11;q13)]  
Fusion : MitelmanRPN2/PMEPA1 [20q11.23/20q13.31]  [t(20;20)(q11;q13)]  
Fusion: TCGAARID3A 19p13.3 PMEPA1 20q13.31 BRCA
Fusion: TCGAPMEPA1 20q13.31 EMILIN3 20q12 BRCA
Fusion: TCGAPMEPA1 20q13.31 PIGP 21q22.13 BRCA
Fusion: TCGAPMEPA1 20q13.31 PTGIS 20q13.13 BRCA
Fusion: TCGAPMEPA1 20q13.31 RALY 20q11.22 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPMEPA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PMEPA1
dbVarPMEPA1
ClinVarPMEPA1
1000_GenomesPMEPA1 
Exome Variant ServerPMEPA1
ExAC (Exome Aggregation Consortium)PMEPA1 (select the gene name)
Genetic variants : HAPMAP56937
Genomic Variants (DGV)PMEPA1 [DGVbeta]
DECIPHERPMEPA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPMEPA1 
Mutations
ICGC Data PortalPMEPA1 
TCGA Data PortalPMEPA1 
Broad Tumor PortalPMEPA1
OASIS PortalPMEPA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPMEPA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPMEPA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PMEPA1
DgiDB (Drug Gene Interaction Database)PMEPA1
DoCM (Curated mutations)PMEPA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PMEPA1 (select a term)
intoGenPMEPA1
Cancer3DPMEPA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606564   
Orphanet
MedgenPMEPA1
Genetic Testing Registry PMEPA1
NextProtQ969W9 [Medical]
TSGene56937
GENETestsPMEPA1
Target ValidationPMEPA1
Huge Navigator PMEPA1 [HugePedia]
snp3D : Map Gene to Disease56937
BioCentury BCIQPMEPA1
ClinGenPMEPA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56937
Chemical/Pharm GKB GenePA162399822
Clinical trialPMEPA1
Miscellaneous
canSAR (ICR)PMEPA1 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePMEPA1
EVEXPMEPA1
GoPubMedPMEPA1
iHOPPMEPA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:00 CEST 2017

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