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PNCK (pregnancy up-regulated nonubiquitous CaM kinase)

Identity

Alias_namespregnancy upregulated non-ubiquitously expressed CaM kinase
pregnancy up-regulated non-ubiquitously expressed CaM kinase
Alias_symbol (synonym)MGC45419
CaMK1b
Other aliasBSTK3
HGNC (Hugo) PNCK
LocusID (NCBI) 139728
Atlas_Id 50469
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153669733 and ends at 153674361 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C16orf45 (16p13.11) / PNCK (Xq28)PNCK (Xq28) / HCFC1 (Xq28)PNCK (Xq28) / TEX28 (Xq28)
PNCK Xq28 / HCFC1 Xq28

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PNCK   13415
Cards
Entrez_Gene (NCBI)PNCK  139728  pregnancy up-regulated nonubiquitous CaM kinase
AliasesBSTK3; CaMK1b
GeneCards (Weizmann)PNCK
Ensembl hg19 (Hinxton)ENSG00000130822 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130822 [Gene_View]  chrX:153669733-153674361 [Contig_View]  PNCK [Vega]
ICGC DataPortalENSG00000130822
TCGA cBioPortalPNCK
AceView (NCBI)PNCK
Genatlas (Paris)PNCK
WikiGenes139728
SOURCE (Princeton)PNCK
Genetics Home Reference (NIH)PNCK
Genomic and cartography
GoldenPath hg38 (UCSC)PNCK  -     chrX:153669733-153674361 -  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PNCK  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblPNCK - Xq28 [CytoView hg19]  PNCK - Xq28 [CytoView hg38]
Mapping of homologs : NCBIPNCK [Mapview hg19]  PNCK [Mapview hg38]
OMIM300680   
Gene and transcription
Genbank (Entrez)AK296067 AK296165 AK296203 AK303746 AK309148
RefSeq transcript (Entrez)NM_001039582 NM_001135740 NM_198452
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PNCK
Cluster EST : UnigeneHs.436667 [ NCBI ]
CGAP (NCI)Hs.436667
Alternative Splicing GalleryENSG00000130822
Gene ExpressionPNCK [ NCBI-GEO ]   PNCK [ EBI - ARRAY_EXPRESS ]   PNCK [ SEEK ]   PNCK [ MEM ]
Gene Expression Viewer (FireBrowse)PNCK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)139728
GTEX Portal (Tissue expression)PNCK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P2M8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P2M8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P2M8
Splice isoforms : SwissVarQ6P2M8
Catalytic activity : Enzyme2.7.11.17 [ Enzyme-Expasy ]   2.7.11.172.7.11.17 [ IntEnz-EBI ]   2.7.11.17 [ BRENDA ]   2.7.11.17 [ KEGG ]   
PhosPhoSitePlusQ6P2M8
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Ca/CaM-dep_Ca-dep_prot_Kinase    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)PNCK
DMDM Disease mutations139728
Blocks (Seattle)PNCK
SuperfamilyQ6P2M8
Human Protein AtlasENSG00000130822
Peptide AtlasQ6P2M8
IPIIPI00913860   IPI00639968   IPI00908942   IPI00641030   IPI00550276   IPI00646231   IPI00748435   IPI00644259   IPI00645880   IPI00413306   IPI00926378   IPI00925116   IPI00927641   
Protein Interaction databases
DIP (DOE-UCLA)Q6P2M8
IntAct (EBI)Q6P2M8
FunCoupENSG00000130822
BioGRIDPNCK
STRING (EMBL)PNCK
ZODIACPNCK
Ontologies - Pathways
QuickGOQ6P2M8
Ontology : AmiGOcalmodulin-dependent protein kinase activity  calmodulin binding  ATP binding  intracellular  nucleus  cytoplasm  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  intracellular signal transduction  
Ontology : EGO-EBIcalmodulin-dependent protein kinase activity  calmodulin binding  ATP binding  intracellular  nucleus  cytoplasm  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  intracellular signal transduction  
NDEx NetworkPNCK
Atlas of Cancer Signalling NetworkPNCK
Wikipedia pathwaysPNCK
Orthology - Evolution
OrthoDB139728
GeneTree (enSembl)ENSG00000130822
Phylogenetic Trees/Animal Genes : TreeFamPNCK
HOVERGENQ6P2M8
HOGENOMQ6P2M8
Homologs : HomoloGenePNCK
Homology/Alignments : Family Browser (UCSC)PNCK
Gene fusions - Rearrangements
Fusion: TCGAPNCK Xq28 HCFC1 Xq28 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPNCK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PNCK
dbVarPNCK
ClinVarPNCK
1000_GenomesPNCK 
Exome Variant ServerPNCK
ExAC (Exome Aggregation Consortium)PNCK (select the gene name)
Genetic variants : HAPMAP139728
Genomic Variants (DGV)PNCK [DGVbeta]
DECIPHERPNCK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPNCK 
Mutations
ICGC Data PortalPNCK 
TCGA Data PortalPNCK 
Broad Tumor PortalPNCK
OASIS PortalPNCK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPNCK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPNCK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PNCK
DgiDB (Drug Gene Interaction Database)PNCK
DoCM (Curated mutations)PNCK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PNCK (select a term)
intoGenPNCK
Cancer3DPNCK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300680   
Orphanet
MedgenPNCK
Genetic Testing Registry PNCK
NextProtQ6P2M8 [Medical]
TSGene139728
GENETestsPNCK
Target ValidationPNCK
Huge Navigator PNCK [HugePedia]
snp3D : Map Gene to Disease139728
BioCentury BCIQPNCK
ClinGenPNCK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD139728
Chemical/Pharm GKB GenePA134988711
Clinical trialPNCK
Miscellaneous
canSAR (ICR)PNCK (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePNCK
EVEXPNCK
GoPubMedPNCK
iHOPPNCK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:05 CEST 2017

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