Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PNLIPRP2 (pancreatic lipase-related protein 2)

Identity

Alias_namespancreatic lipase related protein 2
Alias_symbol (synonym)PLRP2
Other alias
HGNC (Hugo) PNLIPRP2
LocusID (NCBI) 5408
Atlas_Id 72023
Location 10q25.3  [Link to chromosome band 10q25]
Location_base_pair Starts at 118380465 and ends at 118404654 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PNLIPRP2   9157
Cards
Entrez_Gene (NCBI)PNLIPRP2  5408  pancreatic lipase-related protein 2
AliasesPLRP2
GeneCards (Weizmann)PNLIPRP2
Ensembl hg19 (Hinxton)ENSG00000266200 [Gene_View]  chr10:118380465-118404654 [Contig_View]  PNLIPRP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000266200 [Gene_View]  chr10:118380465-118404654 [Contig_View]  PNLIPRP2 [Vega]
ICGC DataPortalENSG00000266200
TCGA cBioPortalPNLIPRP2
AceView (NCBI)PNLIPRP2
Genatlas (Paris)PNLIPRP2
WikiGenes5408
SOURCE (Princeton)PNLIPRP2
Genetics Home Reference (NIH)PNLIPRP2
Genomic and cartography
GoldenPath hg19 (UCSC)PNLIPRP2  -     chr10:118380465-118404654 +  10q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PNLIPRP2  -     10q25.3   [Description]    (hg38-Dec_2013)
EnsemblPNLIPRP2 - 10q25.3 [CytoView hg19]  PNLIPRP2 - 10q25.3 [CytoView hg38]
Mapping of homologs : NCBIPNLIPRP2 [Mapview hg19]  PNLIPRP2 [Mapview hg38]
OMIM604423   
Gene and transcription
Genbank (Entrez)AA367174 AK291492 AK307745 AK308508 AK308511
RefSeq transcript (Entrez)NM_005396
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)PNLIPRP2
Cluster EST : UnigeneHs.423598 [ NCBI ]
CGAP (NCI)Hs.423598
Alternative Splicing GalleryENSG00000266200
Gene ExpressionPNLIPRP2 [ NCBI-GEO ]   PNLIPRP2 [ EBI - ARRAY_EXPRESS ]   PNLIPRP2 [ SEEK ]   PNLIPRP2 [ MEM ]
Gene Expression Viewer (FireBrowse)PNLIPRP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5408
GTEX Portal (Tissue expression)PNLIPRP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54317   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54317  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54317
Splice isoforms : SwissVarP54317
Catalytic activity : Enzyme3.1.1.26 [ Enzyme-Expasy ]   3.1.1.263.1.1.26 [ IntEnz-EBI ]   3.1.1.26 [ BRENDA ]   3.1.1.26 [ KEGG ]   
PhosPhoSitePlusP54317
Domaine pattern : Prosite (Expaxy)LIPASE_SER (PS00120)    PLAT (PS50095)   
Domains : Interpro (EBI)AB_hydrolase    Lipase_LIPH    Lipase_LipOase    Lipase_N    Lipase_panc    PLAT/LH2_dom    TAG_lipase   
Domain families : Pfam (Sanger)Lipase (PF00151)    PLAT (PF01477)   
Domain families : Pfam (NCBI)pfam00151    pfam01477   
Domain families : Smart (EMBL)LH2 (SM00308)  
Conserved Domain (NCBI)PNLIPRP2
DMDM Disease mutations5408
Blocks (Seattle)PNLIPRP2
PDB (SRS)2OXE    2PVS   
PDB (PDBSum)2OXE    2PVS   
PDB (IMB)2OXE    2PVS   
PDB (RSDB)2OXE    2PVS   
Structural Biology KnowledgeBase2OXE    2PVS   
SCOP (Structural Classification of Proteins)2OXE    2PVS   
CATH (Classification of proteins structures)2OXE    2PVS   
SuperfamilyP54317
Human Protein AtlasENSG00000266200
Peptide AtlasP54317
HPRD05110
IPIIPI00005924   
Protein Interaction databases
DIP (DOE-UCLA)P54317
IntAct (EBI)P54317
FunCoupENSG00000266200
BioGRIDPNLIPRP2
STRING (EMBL)PNLIPRP2
ZODIACPNLIPRP2
Ontologies - Pathways
QuickGOP54317
Ontology : AmiGOphospholipase activity  triglyceride lipase activity  calcium ion binding  extracellular region  extracellular space  triglyceride metabolic process  phospholipid catabolic process  galactolipid catabolic process  lipid digestion  small molecule metabolic process  acylglycerol lipase activity  galactolipase activity  
Ontology : EGO-EBIphospholipase activity  triglyceride lipase activity  calcium ion binding  extracellular region  extracellular space  triglyceride metabolic process  phospholipid catabolic process  galactolipid catabolic process  lipid digestion  small molecule metabolic process  acylglycerol lipase activity  galactolipase activity  
Pathways : KEGGGlycerolipid metabolism    Pancreatic secretion    Fat digestion and absorption   
NDEx NetworkPNLIPRP2
Atlas of Cancer Signalling NetworkPNLIPRP2
Wikipedia pathwaysPNLIPRP2
Orthology - Evolution
OrthoDB5408
GeneTree (enSembl)ENSG00000266200
Phylogenetic Trees/Animal Genes : TreeFamPNLIPRP2
HOVERGENP54317
HOGENOMP54317
Homologs : HomoloGenePNLIPRP2
Homology/Alignments : Family Browser (UCSC)PNLIPRP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPNLIPRP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PNLIPRP2
dbVarPNLIPRP2
ClinVarPNLIPRP2
1000_GenomesPNLIPRP2 
Exome Variant ServerPNLIPRP2
ExAC (Exome Aggregation Consortium)PNLIPRP2 (select the gene name)
Genetic variants : HAPMAP5408
Genomic Variants (DGV)PNLIPRP2 [DGVbeta]
DECIPHER (Syndromes)10:118380465-118404654  ENSG00000266200
CONAN: Copy Number AnalysisPNLIPRP2 
Mutations
ICGC Data PortalPNLIPRP2 
TCGA Data PortalPNLIPRP2 
Broad Tumor PortalPNLIPRP2
OASIS PortalPNLIPRP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPNLIPRP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPNLIPRP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PNLIPRP2
DgiDB (Drug Gene Interaction Database)PNLIPRP2
DoCM (Curated mutations)PNLIPRP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PNLIPRP2 (select a term)
intoGenPNLIPRP2
Cancer3DPNLIPRP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604423   
Orphanet
MedgenPNLIPRP2
Genetic Testing Registry PNLIPRP2
NextProtP54317 [Medical]
TSGene5408
GENETestsPNLIPRP2
Huge Navigator PNLIPRP2 [HugePedia]
snp3D : Map Gene to Disease5408
BioCentury BCIQPNLIPRP2
ClinGenPNLIPRP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5408
Chemical/Pharm GKB GenePA33480
Clinical trialPNLIPRP2
Miscellaneous
canSAR (ICR)PNLIPRP2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePNLIPRP2
EVEXPNLIPRP2
GoPubMedPNLIPRP2
iHOPPNLIPRP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:03 CET 2017

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