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PNMT (phenylethanolamine N-methyltransferase)

Identity

Other namesPENT
PNMTase
HGNC (Hugo) PNMT
LocusID (NCBI) 5409
Location 17q12
Location_base_pair Starts at 37824706 and ends at 37826728 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PNMT   9160
Entrez_Gene (NCBI)PNMT  5409  phenylethanolamine N-methyltransferase
Cards
GeneCards (Weizmann)PNMT
Ensembl (Hinxton)ENSG00000141744 [Gene_View]  chr17:37824706-37826728 [Contig_View]  PNMT [Vega]
AceView (NCBI)PNMT
Genatlas (Paris)PNMT
SOURCE (Stanford)NM_002686
Genomic and cartography
GoldenPath (UCSC)PNMT  -  17q12   chr17:37824706-37826728 +  17q12   [Description]    (hg19-Feb_2009)
EnsemblPNMT - 17q12 [CytoView]
Mapping of homologs : NCBIPNMT [Mapview]
OMIM171190   
Gene and transcription
Genbank (Entrez)BC037246 BG394800 CR541815 EU832114 EU832208
RefSeq transcript (SRS)NM_002686
RefSeq transcript (Entrez)NM_002686
RefSeq genomic (SRS)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838435 NW_004078092
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838435 NW_004078092
Consensus coding sequences : CCDS (NCBI)PNMT
Cluster EST : UnigeneHs.1892 [ SRS ] Hs.1892 [ NCBI ]
CGAP (NCI)Hs.1892
Alternative Splicing : Fast-db (Paris)GSHG0012461
Alternative Splicing GalleryENSG00000141744
Gene ExpressionPNMT [ NCBI-GEO ]   PNMT [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11086 (SRS) P11086 (Uniprot)
NextProtP11086
With graphics : InterProP11086
Splice isoforms : SwissVarP11086(Swissvar)
Domaine pattern : Prosite (SRS)NNMT_PNMT_TEMT (PS01100)   
Domaine pattern : Prosite (Expaxy)NNMT_PNMT_TEMT (PS01100)   
Domains : Interpro (SRS)NNMT/PNMT/TEMT_CS    NNMT_TEMT_trans   
Domains : Interpro (EBI)NNMT/PNMT/TEMT_CS    NNMT_TEMT_trans   
Related proteins : CluSTrP11086
Domain families : Pfam (SRS)NNMT_PNMT_TEMT (PF01234)   
Domain families : Pfam (Sanger)NNMT_PNMT_TEMT (PF01234)   
Domain families : Pfam (NCBI)pfam01234   
DMDM5409
Blocks (Seattle)P11086
PDB (SRS)1HNN    1N7I    1N7J    1YZ3    2AN3    2AN4    2AN5    2G70    2G71    2G72    2G8N    2OBF    2ONY    2ONZ    2OPB    3HCA    3HCB    3HCC    3HCD    3HCE    3HCF    3KPJ    3KPU    3KPV    3KPW    3KPY    3KQM    3KQO    3KQP    3KQQ    3KQS    3KQT    3KQV    3KQW    3KQY    3KR0    3KR1    3KR2    4DM3   
PDB (PDBSum)1HNN    1N7I    1N7J    1YZ3    2AN3    2AN4    2AN5    2G70    2G71    2G72    2G8N    2OBF    2ONY    2ONZ    2OPB    3HCA    3HCB    3HCC    3HCD    3HCE    3HCF    3KPJ    3KPU    3KPV    3KPW    3KPY    3KQM    3KQO    3KQP    3KQQ    3KQS    3KQT    3KQV    3KQW    3KQY    3KR0    3KR1    3KR2    4DM3   
PDB (IMB)1HNN    1N7I    1N7J    1YZ3    2AN3    2AN4    2AN5    2G70    2G71    2G72    2G8N    2OBF    2ONY    2ONZ    2OPB    3HCA    3HCB    3HCC    3HCD    3HCE    3HCF    3KPJ    3KPU    3KPV    3KPW    3KPY    3KQM    3KQO    3KQP    3KQQ    3KQS    3KQT    3KQV    3KQW    3KQY    3KR0    3KR1    3KR2    4DM3   
PDB (RSDB)1HNN    1N7I    1N7J    1YZ3    2AN3    2AN4    2AN5    2G70    2G71    2G72    2G8N    2OBF    2ONY    2ONZ    2OPB    3HCA    3HCB    3HCC    3HCD    3HCE    3HCF    3KPJ    3KPU    3KPV    3KPW    3KPY    3KQM    3KQO    3KQP    3KQQ    3KQS    3KQT    3KQV    3KQW    3KQY    3KR0    3KR1    3KR2    4DM3   
Human Protein AtlasENSG00000141744
HPRD07176
IPIIPI00796949   IPI00797601   
Protein Interaction databases
DIP (DOE-UCLA)P11086
IntAct (EBI)P11086
FunCoupENSG00000141744
REACTOMEPNMT
Protein Interaction Database5409
BioGRIDPNMT
InParanoidP11086
Interologous Interaction database P11086
IntegromeDBPNMT
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PNMT
SNP (GeneSNP Utah)PNMT
SNP : HGBasePNMT
Genetic variants : HAPMAPPNMT
Somatic Mutations in Cancer : COSMICPNMT 
CONAN: Copy Number AnalysisPNMT 
Mutations and Diseases : HGMDPNMT
OMIM171190   
GENETests171190   
Disease Genetic AssociationPNMT
Huge Navigator PNMT [HugePedia]  PNMT [HugeCancerGEM]
Genomic VariantsPNMT  PNMT [DGVbeta]
snp3D : Map Gene to Disease5409
General knowledge
Homologs : HomoloGenePNMT
Homology/Alignments : Family Browser (UCSC)PNMT
Phylogenetic Trees/Animal Genes : TreeFamPNMT
Catalytic activity : Enzyme2.1.1.28 [ Enzyme-Expasy ]   2.1.1.28 [ Enzyme-SRS ]   2.1.1.28 [ IntEnz-EBI ]   2.1.1.28 [ BRENDA ]   2.1.1.28 [ KEGG ]   
Chemical/Protein Interactions : CTD5409
Chemical/Pharm GKB GenePA274
Clinical trialPNMT
Cancer Resource (Charite)ENSG00000141744
Ontology : AmiGOphenylethanolamine N-methyltransferase activity  cytosol  cellular nitrogen compound metabolic process  epinephrine biosynthetic process  catecholamine biosynthetic process  small molecule metabolic process  
Ontology : EGO-EBIphenylethanolamine N-methyltransferase activity  cytosol  cellular nitrogen compound metabolic process  epinephrine biosynthetic process  catecholamine biosynthetic process  small molecule metabolic process  
Pathways : KEGGTyrosine metabolism
Other databases
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
PubGenePNMT
iHOPPNMT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:18:21 CEST 2013
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