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PNPO (pyridoxamine 5'-phosphate oxidase)

Identity

Other namesHEL-S-302
PDXPO
HGNC (Hugo) PNPO
LocusID (NCBI) 55163
Atlas_Id 42948
Location 17q21.32
Location_base_pair Starts at 46018889 and ends at 46026674 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PNPO   30260
Cards
Entrez_Gene (NCBI)PNPO  55163  pyridoxamine 5'-phosphate oxidase
GeneCards (Weizmann)PNPO
Ensembl hg19 (Hinxton) [Gene_View]  chr17:46018889-46026674 [Contig_View]  PNPO [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr17:46018889-46026674 [Contig_View]  PNPO [Vega]
TCGA cBioPortalPNPO
AceView (NCBI)PNPO
Genatlas (Paris)PNPO
WikiGenes55163
SOURCE (Princeton)PNPO
Genomic and cartography
GoldenPath hg19 (UCSC)PNPO  -     chr17:46018889-46026674 +  17q21.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PNPO  -     17q21.32   [Description]    (hg38-Dec_2013)
EnsemblPNPO - 17q21.32 [CytoView hg19]  PNPO - 17q21.32 [CytoView hg38]
Mapping of homologs : NCBIPNPO [Mapview hg19]  PNPO [Mapview hg38]
OMIM603287   610090   
Gene and transcription
Genbank (Entrez)AF468030 AK001397 AK223242 AK303536 AK303665
RefSeq transcript (Entrez)NM_018129
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_008744 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)PNPO
Cluster EST : UnigeneHs.631742 [ NCBI ]
CGAP (NCI)Hs.631742
Alternative Splicing : Fast-db (Paris)GSHG0012594
Gene ExpressionPNPO [ NCBI-GEO ]     PNPO [ SEEK ]   PNPO [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVS9 (Uniprot)
NextProtQ9NVS9  [Medical]
With graphics : InterProQ9NVS9
Splice isoforms : SwissVarQ9NVS9 (Swissvar)
Catalytic activity : Enzyme1.4.3.5 [ Enzyme-Expasy ]   1.4.3.51.4.3.5 [ IntEnz-EBI ]   1.4.3.5 [ BRENDA ]   1.4.3.5 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)PYRIDOX_OXIDASE (PS01064)   
Domains : Interpro (EBI)Pyridox_Oxase    Pyridox_Oxase_CS    Pyridox_Oxase_FMN-bd    Pyridoxamine_oxidase_dimer_C    Split_barrel_FMN-bd   
Related proteins : CluSTrQ9NVS9
Domain families : Pfam (Sanger)PNPOx_C (PF10590)    Pyridox_oxidase (PF01243)   
Domain families : Pfam (NCBI)pfam10590    pfam01243   
DMDM Disease mutations55163
Blocks (Seattle)Q9NVS9
PDB (SRS)1NRG    3HY8   
PDB (PDBSum)1NRG    3HY8   
PDB (IMB)1NRG    3HY8   
PDB (RSDB)1NRG    3HY8   
Peptide AtlasQ9NVS9
HPRD04476
IPIIPI00018272   IPI00793232   IPI00792667   IPI01013271   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVS9
IntAct (EBI)Q9NVS9
BioGRIDPNPO
IntegromeDBPNPO
STRING (EMBL)PNPO
Ontologies - Pathways
QuickGOQ9NVS9
Ontology : AmiGOpyridoxamine-phosphate oxidase activity  pyridoxamine-phosphate oxidase activity  nucleoplasm  cytoplasm  cytosol  vitamin metabolic process  water-soluble vitamin metabolic process  pyridoxine biosynthetic process  FMN binding  vitamin B6 metabolic process  pyridoxal phosphate biosynthetic process  small molecule metabolic process  oxidation-reduction process  extracellular exosome  regulation of mitochondrion degradation  
Ontology : EGO-EBIpyridoxamine-phosphate oxidase activity  pyridoxamine-phosphate oxidase activity  nucleoplasm  cytoplasm  cytosol  vitamin metabolic process  water-soluble vitamin metabolic process  pyridoxine biosynthetic process  FMN binding  vitamin B6 metabolic process  pyridoxal phosphate biosynthetic process  small molecule metabolic process  oxidation-reduction process  extracellular exosome  regulation of mitochondrion degradation  
Pathways : KEGGVitamin B6 metabolism   
Protein Interaction DatabasePNPO
DoCM (Curated mutations)PNPO
Wikipedia pathwaysPNPO
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerPNPO [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PNPO
dbVarPNPO
ClinVarPNPO
1000_GenomesPNPO 
Exome Variant ServerPNPO
SNP (GeneSNP Utah)PNPO
SNP : HGBasePNPO
Genetic variants : HAPMAPPNPO
Genomic Variants (DGV)PNPO [DGVbeta]
Mutations
ICGC Data PortalPNPO 
TCGA Data PortalPNPO 
Tumor PortalPNPO
Somatic Mutations in Cancer : COSMICPNPO 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:46018889-46026674
CONAN: Copy Number AnalysisPNPO 
Mutations and Diseases : HGMDPNPO
OMIM603287    610090   
MedgenPNPO
NextProtQ9NVS9 [Medical]
GENETestsPNPO
Disease Genetic AssociationPNPO
Huge Navigator PNPO [HugePedia]  PNPO [HugeCancerGEM]
snp3D : Map Gene to Disease55163
DGIdb (Drug Gene Interaction db)PNPO
General knowledge
Homologs : HomoloGenePNPO
Homology/Alignments : Family Browser (UCSC)PNPO
Phylogenetic Trees/Animal Genes : TreeFamPNPO
Chemical/Protein Interactions : CTD55163
Chemical/Pharm GKB GenePA134915565
Clinical trialPNPO
Other databases
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
CoreMinePNPO
GoPubMedPNPO
iHOPPNPO
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 15:01:16 CEST 2015

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