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PNRC1 (proline rich nuclear receptor coactivator 1)

Identity

Alias_namesPROL2
proline rich 2
proline-rich nuclear receptor coactivator 1
Alias_symbol (synonym)B4-2
PRR2
Other aliasPNAS-145
HGNC (Hugo) PNRC1
LocusID (NCBI) 10957
Atlas_Id 72034
Location 6q15  [Link to chromosome band 6q15]
Location_base_pair Starts at 89080710 and ends at 89085160 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD164 (6q21) / PNRC1 (6q15)PNRC1 (6q15) / EZR (6q25.3)PNRC1 (6q15) / NRDC (1p32.3)
RNASEH2B (13q14.3) / PNRC1 (6q15)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PNRC1   17278
Cards
Entrez_Gene (NCBI)PNRC1  10957  proline rich nuclear receptor coactivator 1
AliasesB4-2; PNAS-145; PROL2; PRR2
GeneCards (Weizmann)PNRC1
Ensembl hg19 (Hinxton)ENSG00000146278 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146278 [Gene_View]  ENSG00000146278 [Sequence]  chr6:89080710-89085160 [Contig_View]  PNRC1 [Vega]
ICGC DataPortalENSG00000146278
TCGA cBioPortalPNRC1
AceView (NCBI)PNRC1
Genatlas (Paris)PNRC1
WikiGenes10957
SOURCE (Princeton)PNRC1
Genetics Home Reference (NIH)PNRC1
Genomic and cartography
GoldenPath hg38 (UCSC)PNRC1  -     chr6:89080710-89085160 +  6q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PNRC1  -     6q15   [Description]    (hg19-Feb_2009)
EnsemblPNRC1 - 6q15 [CytoView hg19]  PNRC1 - 6q15 [CytoView hg38]
Mapping of homologs : NCBIPNRC1 [Mapview hg19]  PNRC1 [Mapview hg38]
OMIM606714   
Gene and transcription
Genbank (Entrez)AF279899 AK130046 AK130722 AK312665 AY303779
RefSeq transcript (Entrez)NM_006813
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PNRC1
Cluster EST : UnigeneHs.75969 [ NCBI ]
CGAP (NCI)Hs.75969
Alternative Splicing GalleryENSG00000146278
Gene ExpressionPNRC1 [ NCBI-GEO ]   PNRC1 [ EBI - ARRAY_EXPRESS ]   PNRC1 [ SEEK ]   PNRC1 [ MEM ]
Gene Expression Viewer (FireBrowse)PNRC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10957
GTEX Portal (Tissue expression)PNRC1
Human Protein AtlasENSG00000146278-PNRC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12796   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12796  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12796
Splice isoforms : SwissVarQ12796
PhosPhoSitePlusQ12796
Domains : Interpro (EBI)PNRC1/2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PNRC1
DMDM Disease mutations10957
Blocks (Seattle)PNRC1
SuperfamilyQ12796
Human Protein Atlas [tissue]ENSG00000146278-PNRC1 [tissue]
Peptide AtlasQ12796
HPRD08412
IPIIPI00009948   IPI00554775   IPI00387006   
Protein Interaction databases
DIP (DOE-UCLA)Q12796
IntAct (EBI)Q12796
FunCoupENSG00000146278
BioGRIDPNRC1
STRING (EMBL)PNRC1
ZODIACPNRC1
Ontologies - Pathways
QuickGOQ12796
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  P-body  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  deadenylation-independent decapping of nuclear-transcribed mRNA  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  P-body  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  deadenylation-independent decapping of nuclear-transcribed mRNA  
NDEx NetworkPNRC1
Atlas of Cancer Signalling NetworkPNRC1
Wikipedia pathwaysPNRC1
Orthology - Evolution
OrthoDB10957
GeneTree (enSembl)ENSG00000146278
Phylogenetic Trees/Animal Genes : TreeFamPNRC1
HOVERGENQ12796
HOGENOMQ12796
Homologs : HomoloGenePNRC1
Homology/Alignments : Family Browser (UCSC)PNRC1
Gene fusions - Rearrangements
Fusion : QuiverPNRC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPNRC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PNRC1
dbVarPNRC1
ClinVarPNRC1
1000_GenomesPNRC1 
Exome Variant ServerPNRC1
ExAC (Exome Aggregation Consortium)ENSG00000146278
GNOMAD BrowserENSG00000146278
Varsome BrowserPNRC1
Genetic variants : HAPMAP10957
Genomic Variants (DGV)PNRC1 [DGVbeta]
DECIPHERPNRC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPNRC1 
Mutations
ICGC Data PortalPNRC1 
TCGA Data PortalPNRC1 
Broad Tumor PortalPNRC1
OASIS PortalPNRC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPNRC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPNRC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PNRC1
DgiDB (Drug Gene Interaction Database)PNRC1
DoCM (Curated mutations)PNRC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PNRC1 (select a term)
intoGenPNRC1
Cancer3DPNRC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606714   
Orphanet
DisGeNETPNRC1
MedgenPNRC1
Genetic Testing Registry PNRC1
NextProtQ12796 [Medical]
TSGene10957
GENETestsPNRC1
Target ValidationPNRC1
Huge Navigator PNRC1 [HugePedia]
snp3D : Map Gene to Disease10957
BioCentury BCIQPNRC1
ClinGenPNRC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10957
Chemical/Pharm GKB GenePA33804
Clinical trialPNRC1
Miscellaneous
canSAR (ICR)PNRC1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePNRC1
EVEXPNRC1
GoPubMedPNRC1
iHOPPNRC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:24:25 CEST 2018

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