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PNRC2 (proline rich nuclear receptor coactivator 2)

Identity

Alias_namesproline-rich nuclear receptor coactivator 2
Other alias-
HGNC (Hugo) PNRC2
LocusID (NCBI) 55629
Atlas_Id 72035
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 23959811 and ends at 23963459 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRRC16A (6p22.2) / PNRC2 (1p36.11)PNRC2 (1p36.11) / LRRC16A (6p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PNRC2   23158
Cards
Entrez_Gene (NCBI)PNRC2  55629  proline rich nuclear receptor coactivator 2
Aliases
GeneCards (Weizmann)PNRC2
Ensembl hg19 (Hinxton)ENSG00000189266 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189266 [Gene_View]  chr1:23959811-23963459 [Contig_View]  PNRC2 [Vega]
ICGC DataPortalENSG00000189266
TCGA cBioPortalPNRC2
AceView (NCBI)PNRC2
Genatlas (Paris)PNRC2
WikiGenes55629
SOURCE (Princeton)PNRC2
Genetics Home Reference (NIH)PNRC2
Genomic and cartography
GoldenPath hg38 (UCSC)PNRC2  -     chr1:23959811-23963459 +  1p36.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PNRC2  -     1p36.11   [Description]    (hg19-Feb_2009)
EnsemblPNRC2 - 1p36.11 [CytoView hg19]  PNRC2 - 1p36.11 [CytoView hg38]
Mapping of homologs : NCBIPNRC2 [Mapview hg19]  PNRC2 [Mapview hg38]
OMIM611882   
Gene and transcription
Genbank (Entrez)AF151042 AF374386 AK000319 AK024774 AK300522
RefSeq transcript (Entrez)NM_017761
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PNRC2
Cluster EST : UnigeneHs.716935 [ NCBI ]
CGAP (NCI)Hs.716935
Alternative Splicing GalleryENSG00000189266
Gene ExpressionPNRC2 [ NCBI-GEO ]   PNRC2 [ EBI - ARRAY_EXPRESS ]   PNRC2 [ SEEK ]   PNRC2 [ MEM ]
Gene Expression Viewer (FireBrowse)PNRC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55629
GTEX Portal (Tissue expression)PNRC2
Human Protein AtlasENSG00000189266-PNRC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPJ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPJ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPJ4
Splice isoforms : SwissVarQ9NPJ4
PhosPhoSitePlusQ9NPJ4
Domains : Interpro (EBI)PNRC1/2    PNRC2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PNRC2
DMDM Disease mutations55629
Blocks (Seattle)PNRC2
PDB (SRS)4B6H    5KQ1    5KQ4   
PDB (PDBSum)4B6H    5KQ1    5KQ4   
PDB (IMB)4B6H    5KQ1    5KQ4   
PDB (RSDB)4B6H    5KQ1    5KQ4   
Structural Biology KnowledgeBase4B6H    5KQ1    5KQ4   
SCOP (Structural Classification of Proteins)4B6H    5KQ1    5KQ4   
CATH (Classification of proteins structures)4B6H    5KQ1    5KQ4   
SuperfamilyQ9NPJ4
Human Protein Atlas [tissue]ENSG00000189266-PNRC2 [tissue]
Peptide AtlasQ9NPJ4
HPRD17871
IPIIPI00015681   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPJ4
IntAct (EBI)Q9NPJ4
FunCoupENSG00000189266
BioGRIDPNRC2
STRING (EMBL)PNRC2
ZODIACPNRC2
Ontologies - Pathways
QuickGOQ9NPJ4
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  P-body  protein binding  nucleus  nucleoplasm  Golgi apparatus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  deadenylation-independent decapping of nuclear-transcribed mRNA  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  P-body  protein binding  nucleus  nucleoplasm  Golgi apparatus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  deadenylation-independent decapping of nuclear-transcribed mRNA  
NDEx NetworkPNRC2
Atlas of Cancer Signalling NetworkPNRC2
Wikipedia pathwaysPNRC2
Orthology - Evolution
OrthoDB55629
GeneTree (enSembl)ENSG00000189266
Phylogenetic Trees/Animal Genes : TreeFamPNRC2
HOVERGENQ9NPJ4
HOGENOMQ9NPJ4
Homologs : HomoloGenePNRC2
Homology/Alignments : Family Browser (UCSC)PNRC2
Gene fusions - Rearrangements
Tumor Fusion PortalPNRC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPNRC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PNRC2
dbVarPNRC2
ClinVarPNRC2
1000_GenomesPNRC2 
Exome Variant ServerPNRC2
ExAC (Exome Aggregation Consortium)ENSG00000189266
GNOMAD BrowserENSG00000189266
Genetic variants : HAPMAP55629
Genomic Variants (DGV)PNRC2 [DGVbeta]
DECIPHERPNRC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPNRC2 
Mutations
ICGC Data PortalPNRC2 
TCGA Data PortalPNRC2 
Broad Tumor PortalPNRC2
OASIS PortalPNRC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPNRC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPNRC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PNRC2
DgiDB (Drug Gene Interaction Database)PNRC2
DoCM (Curated mutations)PNRC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PNRC2 (select a term)
intoGenPNRC2
Cancer3DPNRC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611882   
Orphanet
DisGeNETPNRC2
MedgenPNRC2
Genetic Testing Registry PNRC2
NextProtQ9NPJ4 [Medical]
TSGene55629
GENETestsPNRC2
Target ValidationPNRC2
Huge Navigator PNRC2 [HugePedia]
snp3D : Map Gene to Disease55629
BioCentury BCIQPNRC2
ClinGenPNRC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55629
Chemical/Pharm GKB GenePA134931421
Clinical trialPNRC2
Miscellaneous
canSAR (ICR)PNRC2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRiFs/TD>Gene References Into Functions (Entrez)
CoreMinePNRC2
EVEXPNRC2
GoPubMedPNRC2
iHOPPNRC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:02:24 CET 2017

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