Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

POC1A (POC1 centriolar protein A)

Identity

Alias (NCBI)PIX2
SOFT
WDR51A
HGNC (Hugo) POC1A
HGNC Alias symbDKFZP434C245
HGNC Previous nameWDR51A
HGNC Previous nameWD repeat domain 51A
 POC1 centriolar protein homolog A (Chlamydomonas)
LocusID (NCBI) 25886
Atlas_Id 40313
Location 3p21.2  [Link to chromosome band 3p21]
Location_base_pair Starts at 52075226 and ends at 52154423 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABHD14B (3p21.2) / POC1A (3p21.2)PCNT (21q22.3) / POC1A (3p21.2)POC1A (3p21.2) / TBC1D22A (22q13.31)
VPRBP (3p21.2) / POC1A (3p21.2)ABHD14B 3p21.2 / POC1A 3p21.2PCNT 21q22.3 / POC1A 3p21.2
VPRBP 3p21.2 / POC1A 3p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)POC1A   24488
Cards
Entrez_Gene (NCBI)POC1A    POC1 centriolar protein A
AliasesPIX2; SOFT; WDR51A
GeneCards (Weizmann)POC1A
Ensembl hg19 (Hinxton)ENSG00000164087 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164087 [Gene_View]  ENSG00000164087 [Sequence]  chr3:52075226-52154423 [Contig_View]  POC1A [Vega]
ICGC DataPortalENSG00000164087
TCGA cBioPortalPOC1A
AceView (NCBI)POC1A
Genatlas (Paris)POC1A
SOURCE (Princeton)POC1A
Genetics Home Reference (NIH)POC1A
Genomic and cartography
GoldenPath hg38 (UCSC)POC1A  -     chr3:52075226-52154423 -  3p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POC1A  -     3p21.2   [Description]    (hg19-Feb_2009)
GoldenPathPOC1A - 3p21.2 [CytoView hg19]  POC1A - 3p21.2 [CytoView hg38]
ImmunoBaseENSG00000164087
Genome Data Viewer NCBIPOC1A [Mapview hg19]  
OMIM614783   614813   
Gene and transcription
Genbank (Entrez)AF088072 AK075289 AK315688 AL117629 BC007417
RefSeq transcript (Entrez)NM_001161580 NM_001161581 NM_015426
Consensus coding sequences : CCDS (NCBI)POC1A
Gene ExpressionPOC1A [ NCBI-GEO ]   POC1A [ EBI - ARRAY_EXPRESS ]   POC1A [ SEEK ]   POC1A [ MEM ]
Gene Expression Viewer (FireBrowse)POC1A [ Firebrowse - Broad ]
GenevisibleExpression of POC1A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25886
GTEX Portal (Tissue expression)POC1A
Human Protein AtlasENSG00000164087-POC1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBT0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBT0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBT0
PhosPhoSitePlusQ8NBT0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)POC1A
SuperfamilyQ8NBT0
AlphaFold pdb e-kbQ8NBT0   
Human Protein Atlas [tissue]ENSG00000164087-POC1A [tissue]
HPRD08523
Protein Interaction databases
DIP (DOE-UCLA)Q8NBT0
IntAct (EBI)Q8NBT0
BioGRIDPOC1A
STRING (EMBL)POC1A
ZODIACPOC1A
Ontologies - Pathways
QuickGOQ8NBT0
Ontology : AmiGOspindle pole  protein binding  cytoplasm  centrosome  centriole  cell projection organization  ciliary basal body  
Ontology : EGO-EBIspindle pole  protein binding  cytoplasm  centrosome  centriole  cell projection organization  ciliary basal body  
NDEx NetworkPOC1A
Atlas of Cancer Signalling NetworkPOC1A
Wikipedia pathwaysPOC1A
Orthology - Evolution
OrthoDB25886
GeneTree (enSembl)ENSG00000164087
Phylogenetic Trees/Animal Genes : TreeFamPOC1A
Homologs : HomoloGenePOC1A
Homology/Alignments : Family Browser (UCSC)POC1A
Gene fusions - Rearrangements
Fusion : MitelmanABHD14B/POC1A [3p21.2/3p21.2]  
Fusion : MitelmanPCNT/POC1A [21q22.3/3p21.2]  
Fusion : MitelmanVPRBP/POC1A [3p21.2/3p21.2]  
Fusion : QuiverPOC1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOC1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POC1A
dbVarPOC1A
ClinVarPOC1A
MonarchPOC1A
1000_GenomesPOC1A 
Exome Variant ServerPOC1A
GNOMAD BrowserENSG00000164087
Varsome BrowserPOC1A
ACMGPOC1A variants
VarityQ8NBT0
Genomic Variants (DGV)POC1A [DGVbeta]
DECIPHERPOC1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOC1A 
Mutations
ICGC Data PortalPOC1A 
TCGA Data PortalPOC1A 
Broad Tumor PortalPOC1A
OASIS PortalPOC1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOC1A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPOC1A
Mutations and Diseases : HGMDPOC1A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPOC1A
DgiDB (Drug Gene Interaction Database)POC1A
DoCM (Curated mutations)POC1A
CIViC (Clinical Interpretations of Variants in Cancer)POC1A
Cancer3DPOC1A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614783    614813   
Orphanet21480   
DisGeNETPOC1A
MedgenPOC1A
Genetic Testing Registry POC1A
NextProtQ8NBT0 [Medical]
GENETestsPOC1A
Target ValidationPOC1A
Huge Navigator POC1A [HugePedia]
ClinGenPOC1A
Clinical trials, drugs, therapy
MyCancerGenomePOC1A
Protein Interactions : CTDPOC1A
Pharm GKB GenePA165698089
PharosQ8NBT0
Clinical trialPOC1A
Miscellaneous
canSAR (ICR)POC1A
HarmonizomePOC1A
DataMed IndexPOC1A
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPOC1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:25:59 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.