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POC1A (POC1 centriolar protein A)

Identity

Alias_namesWDR51A
WD repeat domain 51A
POC1 centriolar protein homolog A (Chlamydomonas)
Alias_symbol (synonym)DKFZP434C245
Other aliasPIX2
SOFT
HGNC (Hugo) POC1A
LocusID (NCBI) 25886
Atlas_Id 40313
Location 3p21.2  [Link to chromosome band 3p21]
Location_base_pair Starts at 52109249 and ends at 52188706 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABHD14B (3p21.2) / POC1A (3p21.2)PCNT (21q22.3) / POC1A (3p21.2)POC1A (3p21.2) / TBC1D22A (22q13.31)
VPRBP (3p21.2) / POC1A (3p21.2)ABHD14B 3p21.2 / POC1A 3p21.2PCNT 21q22.3 / POC1A 3p21.2
VPRBP 3p21.2 / POC1A 3p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POC1A   24488
Cards
Entrez_Gene (NCBI)POC1A  25886  POC1 centriolar protein A
AliasesPIX2; SOFT; WDR51A
GeneCards (Weizmann)POC1A
Ensembl hg19 (Hinxton)ENSG00000164087 [Gene_View]  chr3:52109249-52188706 [Contig_View]  POC1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000164087 [Gene_View]  chr3:52109249-52188706 [Contig_View]  POC1A [Vega]
ICGC DataPortalENSG00000164087
TCGA cBioPortalPOC1A
AceView (NCBI)POC1A
Genatlas (Paris)POC1A
WikiGenes25886
SOURCE (Princeton)POC1A
Genetics Home Reference (NIH)POC1A
Genomic and cartography
GoldenPath hg19 (UCSC)POC1A  -     chr3:52109249-52188706 -  3p21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)POC1A  -     3p21.2   [Description]    (hg38-Dec_2013)
EnsemblPOC1A - 3p21.2 [CytoView hg19]  POC1A - 3p21.2 [CytoView hg38]
Mapping of homologs : NCBIPOC1A [Mapview hg19]  POC1A [Mapview hg38]
OMIM614783   614813   
Gene and transcription
Genbank (Entrez)AF088072 AK075289 AK315688 AL117629 BC007417
RefSeq transcript (Entrez)NM_001161580 NM_001161581 NM_015426
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_032947 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)POC1A
Cluster EST : UnigeneHs.476306 [ NCBI ]
CGAP (NCI)Hs.476306
Alternative Splicing GalleryENSG00000164087
Gene ExpressionPOC1A [ NCBI-GEO ]   POC1A [ EBI - ARRAY_EXPRESS ]   POC1A [ SEEK ]   POC1A [ MEM ]
Gene Expression Viewer (FireBrowse)POC1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25886
GTEX Portal (Tissue expression)POC1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBT0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBT0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBT0
Splice isoforms : SwissVarQ8NBT0
PhosPhoSitePlusQ8NBT0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)POC1A
DMDM Disease mutations25886
Blocks (Seattle)POC1A
SuperfamilyQ8NBT0
Human Protein AtlasENSG00000164087
Peptide AtlasQ8NBT0
HPRD08523
IPIIPI00171440   IPI00719213   IPI00936600   
Protein Interaction databases
DIP (DOE-UCLA)Q8NBT0
IntAct (EBI)Q8NBT0
FunCoupENSG00000164087
BioGRIDPOC1A
STRING (EMBL)POC1A
ZODIACPOC1A
Ontologies - Pathways
QuickGOQ8NBT0
Ontology : AmiGOspindle pole  protein binding  centrosome  centriole  cell projection organization  ciliary basal body  
Ontology : EGO-EBIspindle pole  protein binding  centrosome  centriole  cell projection organization  ciliary basal body  
NDEx NetworkPOC1A
Atlas of Cancer Signalling NetworkPOC1A
Wikipedia pathwaysPOC1A
Orthology - Evolution
OrthoDB25886
GeneTree (enSembl)ENSG00000164087
Phylogenetic Trees/Animal Genes : TreeFamPOC1A
HOVERGENQ8NBT0
HOGENOMQ8NBT0
Homologs : HomoloGenePOC1A
Homology/Alignments : Family Browser (UCSC)POC1A
Gene fusions - Rearrangements
Fusion : MitelmanABHD14B/POC1A [3p21.2/3p21.2]  [t(3;3)(p21;p21)]  
Fusion : MitelmanPCNT/POC1A [21q22.3/3p21.2]  [t(3;21)(p21;q22)]  
Fusion : MitelmanVPRBP/POC1A [3p21.2/3p21.2]  [t(3;3)(p21;p21)]  
Fusion: TCGAABHD14B 3p21.2 POC1A 3p21.2 BRCA
Fusion: TCGAPCNT 21q22.3 POC1A 3p21.2 HNSC
Fusion: TCGAVPRBP 3p21.2 POC1A 3p21.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOC1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POC1A
dbVarPOC1A
ClinVarPOC1A
1000_GenomesPOC1A 
Exome Variant ServerPOC1A
ExAC (Exome Aggregation Consortium)POC1A (select the gene name)
Genetic variants : HAPMAP25886
Genomic Variants (DGV)POC1A [DGVbeta]
DECIPHER (Syndromes)3:52109249-52188706  ENSG00000164087
CONAN: Copy Number AnalysisPOC1A 
Mutations
ICGC Data PortalPOC1A 
TCGA Data PortalPOC1A 
Broad Tumor PortalPOC1A
OASIS PortalPOC1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOC1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOC1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POC1A
DgiDB (Drug Gene Interaction Database)POC1A
DoCM (Curated mutations)POC1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POC1A (select a term)
intoGenPOC1A
Cancer3DPOC1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614783    614813   
Orphanet21480   
MedgenPOC1A
Genetic Testing Registry POC1A
NextProtQ8NBT0 [Medical]
TSGene25886
GENETestsPOC1A
Huge Navigator POC1A [HugePedia]
snp3D : Map Gene to Disease25886
BioCentury BCIQPOC1A
ClinGenPOC1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25886
Chemical/Pharm GKB GenePA165698089
Clinical trialPOC1A
Miscellaneous
canSAR (ICR)POC1A (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOC1A
EVEXPOC1A
GoPubMedPOC1A
iHOPPOC1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:22:04 CET 2017

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