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POC1B (POC1 centriolar protein B)

Identity

Alias_namesWDR51B
WD repeat domain 51B
POC1 centriolar protein homolog B (Chlamydomonas)
Alias_symbol (synonym)TUWD12
FLJ14923
Other aliasCORD20
PIX1
HGNC (Hugo) POC1B
LocusID (NCBI) 282809
Atlas_Id 56598
Location 12q21.33  [Link to chromosome band 12q21]
Location_base_pair Starts at 89419721 and ends at 89525567 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LAMC2 (1q25.3) / POC1B (12q21.33)MTAP (9p21.3) / POC1B (12q21.33)POC1B (12q21.33) / SERPINE1 (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POC1B   30836
Cards
Entrez_Gene (NCBI)POC1B  282809  POC1 centriolar protein B
AliasesCORD20; PIX1; TUWD12; WDR51B
GeneCards (Weizmann)POC1B
Ensembl hg19 (Hinxton)ENSG00000139323 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139323 [Gene_View]  chr12:89419721-89525567 [Contig_View]  POC1B [Vega]
ICGC DataPortalENSG00000139323
TCGA cBioPortalPOC1B
AceView (NCBI)POC1B
Genatlas (Paris)POC1B
WikiGenes282809
SOURCE (Princeton)POC1B
Genetics Home Reference (NIH)POC1B
Genomic and cartography
GoldenPath hg38 (UCSC)POC1B  -     chr12:89419721-89525567 -  12q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POC1B  -     12q21.33   [Description]    (hg19-Feb_2009)
EnsemblPOC1B - 12q21.33 [CytoView hg19]  POC1B - 12q21.33 [CytoView hg38]
Mapping of homologs : NCBIPOC1B [Mapview hg19]  POC1B [Mapview hg38]
OMIM614784   615973   
Gene and transcription
Genbank (Entrez)AB053266 AK027829 AK074772 AK123106 AK123625
RefSeq transcript (Entrez)NM_001199777 NM_172240
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POC1B
Cluster EST : UnigeneHs.604487 [ NCBI ]
CGAP (NCI)Hs.604487
Alternative Splicing GalleryENSG00000139323
Gene ExpressionPOC1B [ NCBI-GEO ]   POC1B [ EBI - ARRAY_EXPRESS ]   POC1B [ SEEK ]   POC1B [ MEM ]
Gene Expression Viewer (FireBrowse)POC1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)282809
GTEX Portal (Tissue expression)POC1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TC44   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TC44  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TC44
Splice isoforms : SwissVarQ8TC44
PhosPhoSitePlusQ8TC44
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)POC1B
DMDM Disease mutations282809
Blocks (Seattle)POC1B
SuperfamilyQ8TC44
Human Protein AtlasENSG00000139323
Peptide AtlasQ8TC44
HPRD18301
IPIIPI00152269   IPI00910574   IPI00446434   IPI00796655   IPI01022781   IPI01012290   IPI01021902   IPI01022987   
Protein Interaction databases
DIP (DOE-UCLA)Q8TC44
IntAct (EBI)Q8TC44
FunCoupENSG00000139323
BioGRIDPOC1B
STRING (EMBL)POC1B
ZODIACPOC1B
Ontologies - Pathways
QuickGOQ8TC44
Ontology : AmiGOspindle pole  retina homeostasis  protein binding  centrosome  centriole  cell proliferation  ciliary basal body  cilium assembly  
Ontology : EGO-EBIspindle pole  retina homeostasis  protein binding  centrosome  centriole  cell proliferation  ciliary basal body  cilium assembly  
NDEx NetworkPOC1B
Atlas of Cancer Signalling NetworkPOC1B
Wikipedia pathwaysPOC1B
Orthology - Evolution
OrthoDB282809
GeneTree (enSembl)ENSG00000139323
Phylogenetic Trees/Animal Genes : TreeFamPOC1B
HOVERGENQ8TC44
HOGENOMQ8TC44
Homologs : HomoloGenePOC1B
Homology/Alignments : Family Browser (UCSC)POC1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOC1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POC1B
dbVarPOC1B
ClinVarPOC1B
1000_GenomesPOC1B 
Exome Variant ServerPOC1B
ExAC (Exome Aggregation Consortium)POC1B (select the gene name)
Genetic variants : HAPMAP282809
Genomic Variants (DGV)POC1B [DGVbeta]
DECIPHERPOC1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOC1B 
Mutations
ICGC Data PortalPOC1B 
TCGA Data PortalPOC1B 
Broad Tumor PortalPOC1B
OASIS PortalPOC1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOC1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOC1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POC1B
DgiDB (Drug Gene Interaction Database)POC1B
DoCM (Curated mutations)POC1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POC1B (select a term)
intoGenPOC1B
Cancer3DPOC1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614784    615973   
Orphanet1843   
MedgenPOC1B
Genetic Testing Registry POC1B
NextProtQ8TC44 [Medical]
TSGene282809
GENETestsPOC1B
Target ValidationPOC1B
Huge Navigator POC1B [HugePedia]
snp3D : Map Gene to Disease282809
BioCentury BCIQPOC1B
ClinGenPOC1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD282809
Chemical/Pharm GKB GenePA165513299
Clinical trialPOC1B
Miscellaneous
canSAR (ICR)POC1B (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOC1B
EVEXPOC1B
GoPubMedPOC1B
iHOPPOC1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:09 CEST 2017

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