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PODXL (podocalyxin like)

Identity

Alias (NCBI)Gp200
PC
PCLP
PCLP-1
PDX
PODXL1
gp135
HGNC (Hugo) PODXL
HGNC Alias symbPCLP
Gp200
PC
PODXL1
PDX
gp135
HGNC Previous namepodocalyxin-like
LocusID (NCBI) 5420
Atlas_Id 45807
Location 7q32.3  [Link to chromosome band 7q32]
Location_base_pair Starts at 131500271 and ends at 131556628 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATAD2 (8q24.13) / PODXL (7q32.3)PODXL (7q32.3) / C5orf38 (5p15.33)PODXL (7q32.3) / TTC19 (17p12)
PODXL (7q32.3) / UBA52 (19p13.11)TRAP1 (16p13.3) / PODXL (7q32.3)ATAD2 8q24.13 / PODXL 7q32.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PODXL   9171
Cards
Entrez_Gene (NCBI)PODXL    podocalyxin like
AliasesGp200; PC; PCLP; PCLP-1; 
PDX; PODXL1; gp135
GeneCards (Weizmann)PODXL
Ensembl hg19 (Hinxton)ENSG00000128567 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128567 [Gene_View]  ENSG00000128567 [Sequence]  chr7:131500271-131556628 [Contig_View]  PODXL [Vega]
ICGC DataPortalENSG00000128567
TCGA cBioPortalPODXL
AceView (NCBI)PODXL
Genatlas (Paris)PODXL
SOURCE (Princeton)PODXL
Genetics Home Reference (NIH)PODXL
Genomic and cartography
GoldenPath hg38 (UCSC)PODXL  -     chr7:131500271-131556628 -  7q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PODXL  -     7q32.3   [Description]    (hg19-Feb_2009)
GoldenPathPODXL - 7q32.3 [CytoView hg19]  PODXL - 7q32.3 [CytoView hg38]
ImmunoBaseENSG00000128567
Genome Data Viewer NCBIPODXL [Mapview hg19]  
OMIM602632   
Gene and transcription
Genbank (Entrez)AK055816 AK223573 BC042466 BC093730 BC112035
RefSeq transcript (Entrez)NM_001018111 NM_005397
Consensus coding sequences : CCDS (NCBI)PODXL
Gene ExpressionPODXL [ NCBI-GEO ]   PODXL [ EBI - ARRAY_EXPRESS ]   PODXL [ SEEK ]   PODXL [ MEM ]
Gene Expression Viewer (FireBrowse)PODXL [ Firebrowse - Broad ]
GenevisibleExpression of PODXL in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5420
GTEX Portal (Tissue expression)PODXL
Human Protein AtlasENSG00000128567-PODXL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00592   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00592  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00592
PhosPhoSitePlusO00592
Domains : Interpro (EBI)CD34/Podocalyxin    PODXL   
Domain families : Pfam (Sanger)CD34_antigen (PF06365)   
Domain families : Pfam (NCBI)pfam06365   
Conserved Domain (NCBI)PODXL
SuperfamilyO00592
AlphaFold pdb e-kbO00592   
Human Protein Atlas [tissue]ENSG00000128567-PODXL [tissue]
HPRD04025
Protein Interaction databases
DIP (DOE-UCLA)O00592
IntAct (EBI)O00592
BioGRIDPODXL
STRING (EMBL)PODXL
ZODIACPODXL
Ontologies - Pathways
QuickGOO00592
Ontology : AmiGOruffle  protein binding  extracellular space  nucleolus  cytoplasm  plasma membrane  integral component of plasma membrane  cell adhesion  negative regulation of cell adhesion  apical plasma membrane  apical plasma membrane  cell migration  cell migration  negative regulation of cell-cell adhesion  negative regulation of cell-cell adhesion  lamellipodium  filopodium  positive regulation of cell migration  microvillus membrane  microvillus membrane  regulation of microvillus assembly  regulation of microvillus assembly  positive regulation of cell-cell adhesion mediated by integrin  positive regulation of cell-cell adhesion mediated by integrin  centriolar satellite  slit diaphragm  intracellular membrane-bounded organelle  membrane raft  extracellular exosome  extracellular exosome  glomerular visceral epithelial cell development  epithelial tube formation  
Ontology : EGO-EBIruffle  protein binding  extracellular space  nucleolus  cytoplasm  plasma membrane  integral component of plasma membrane  cell adhesion  negative regulation of cell adhesion  apical plasma membrane  apical plasma membrane  cell migration  cell migration  negative regulation of cell-cell adhesion  negative regulation of cell-cell adhesion  lamellipodium  filopodium  positive regulation of cell migration  microvillus membrane  microvillus membrane  regulation of microvillus assembly  regulation of microvillus assembly  positive regulation of cell-cell adhesion mediated by integrin  positive regulation of cell-cell adhesion mediated by integrin  centriolar satellite  slit diaphragm  intracellular membrane-bounded organelle  membrane raft  extracellular exosome  extracellular exosome  glomerular visceral epithelial cell development  epithelial tube formation  
NDEx NetworkPODXL
Atlas of Cancer Signalling NetworkPODXL
Wikipedia pathwaysPODXL
Orthology - Evolution
OrthoDB5420
GeneTree (enSembl)ENSG00000128567
Phylogenetic Trees/Animal Genes : TreeFamPODXL
Homologs : HomoloGenePODXL
Homology/Alignments : Family Browser (UCSC)PODXL
Gene fusions - Rearrangements
Fusion : MitelmanATAD2/PODXL [8q24.13/7q32.3]  
Fusion : QuiverPODXL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPODXL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PODXL
dbVarPODXL
ClinVarPODXL
MonarchPODXL
1000_GenomesPODXL 
Exome Variant ServerPODXL
GNOMAD BrowserENSG00000128567
Varsome BrowserPODXL
ACMGPODXL variants
VarityO00592
Genomic Variants (DGV)PODXL [DGVbeta]
DECIPHERPODXL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPODXL 
Mutations
ICGC Data PortalPODXL 
TCGA Data PortalPODXL 
Broad Tumor PortalPODXL
OASIS PortalPODXL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPODXL  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPODXL
Mutations and Diseases : HGMDPODXL
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPODXL
DgiDB (Drug Gene Interaction Database)PODXL
DoCM (Curated mutations)PODXL
CIViC (Clinical Interpretations of Variants in Cancer)PODXL
Cancer3DPODXL
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602632   
Orphanet
DisGeNETPODXL
MedgenPODXL
Genetic Testing Registry PODXL
NextProtO00592 [Medical]
GENETestsPODXL
Target ValidationPODXL
Huge Navigator PODXL [HugePedia]
ClinGenPODXL
Clinical trials, drugs, therapy
MyCancerGenomePODXL
Protein Interactions : CTDPODXL
Pharm GKB GenePA33493
PharosO00592
Clinical trialPODXL
Miscellaneous
canSAR (ICR)PODXL
HarmonizomePODXL
DataMed IndexPODXL
Probes
Litterature
PubMed118 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPODXL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:26:00 CEST 2021

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