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PODXL (podocalyxin like)

Identity

Alias_namespodocalyxin-like
Alias_symbol (synonym)PCLP
Gp200
PC
Other aliasPCLP-1
HGNC (Hugo) PODXL
LocusID (NCBI) 5420
Atlas_Id 45807
Location 7q32.3  [Link to chromosome band 7q32]
Location_base_pair Starts at 131500262 and ends at 131556617 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATAD2 (8q24.13) / PODXL (7q32.3)PODXL (7q32.3) / C5orf38 (5p15.33)PODXL (7q32.3) / TTC19 (17p12)
PODXL (7q32.3) / UBA52 (19p13.11)TRAP1 (16p13.3) / PODXL (7q32.3)ATAD2 8q24.13 / PODXL 7q32.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PODXL   9171
Cards
Entrez_Gene (NCBI)PODXL  5420  podocalyxin like
AliasesGp200; PC; PCLP; PCLP-1
GeneCards (Weizmann)PODXL
Ensembl hg19 (Hinxton)ENSG00000128567 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128567 [Gene_View]  chr7:131500262-131556617 [Contig_View]  PODXL [Vega]
ICGC DataPortalENSG00000128567
TCGA cBioPortalPODXL
AceView (NCBI)PODXL
Genatlas (Paris)PODXL
WikiGenes5420
SOURCE (Princeton)PODXL
Genetics Home Reference (NIH)PODXL
Genomic and cartography
GoldenPath hg38 (UCSC)PODXL  -     chr7:131500262-131556617 -  7q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PODXL  -     7q32.3   [Description]    (hg19-Feb_2009)
EnsemblPODXL - 7q32.3 [CytoView hg19]  PODXL - 7q32.3 [CytoView hg38]
Mapping of homologs : NCBIPODXL [Mapview hg19]  PODXL [Mapview hg38]
OMIM602632   
Gene and transcription
Genbank (Entrez)AK055816 AK223573 BC042466 BC093730 BC112035
RefSeq transcript (Entrez)NM_001018111 NM_005397
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PODXL
Cluster EST : UnigeneHs.744213 [ NCBI ]
CGAP (NCI)Hs.744213
Alternative Splicing GalleryENSG00000128567
Gene ExpressionPODXL [ NCBI-GEO ]   PODXL [ EBI - ARRAY_EXPRESS ]   PODXL [ SEEK ]   PODXL [ MEM ]
Gene Expression Viewer (FireBrowse)PODXL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5420
GTEX Portal (Tissue expression)PODXL
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00592   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00592  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00592
Splice isoforms : SwissVarO00592
PhosPhoSitePlusO00592
Domains : Interpro (EBI)CD34/Podocalyxin    PODXL   
Domain families : Pfam (Sanger)CD34_antigen (PF06365)   
Domain families : Pfam (NCBI)pfam06365   
Conserved Domain (NCBI)PODXL
DMDM Disease mutations5420
Blocks (Seattle)PODXL
SuperfamilyO00592
Human Protein AtlasENSG00000128567
Peptide AtlasO00592
HPRD04025
IPIIPI01018674   IPI00604773   IPI01012180   IPI00926191   IPI00299116   
Protein Interaction databases
DIP (DOE-UCLA)O00592
IntAct (EBI)O00592
FunCoupENSG00000128567
BioGRIDPODXL
STRING (EMBL)PODXL
ZODIACPODXL
Ontologies - Pathways
QuickGOO00592
Ontology : AmiGOruffle  protein binding  extracellular space  nucleolus  cytoplasm  microtubule organizing center  plasma membrane  integral component of plasma membrane  cell adhesion  negative regulation of cell adhesion  apical plasma membrane  cell migration  negative regulation of cell-cell adhesion  lamellipodium  filopodium  positive regulation of cell migration  microvillus membrane  regulation of microvillus assembly  positive regulation of cell-cell adhesion mediated by integrin  slit diaphragm  intracellular membrane-bounded organelle  cell body  membrane raft  leukocyte migration  extracellular exosome  glomerular visceral epithelial cell development  epithelial tube formation  
Ontology : EGO-EBIruffle  protein binding  extracellular space  nucleolus  cytoplasm  microtubule organizing center  plasma membrane  integral component of plasma membrane  cell adhesion  negative regulation of cell adhesion  apical plasma membrane  cell migration  negative regulation of cell-cell adhesion  lamellipodium  filopodium  positive regulation of cell migration  microvillus membrane  regulation of microvillus assembly  positive regulation of cell-cell adhesion mediated by integrin  slit diaphragm  intracellular membrane-bounded organelle  cell body  membrane raft  leukocyte migration  extracellular exosome  glomerular visceral epithelial cell development  epithelial tube formation  
NDEx NetworkPODXL
Atlas of Cancer Signalling NetworkPODXL
Wikipedia pathwaysPODXL
Orthology - Evolution
OrthoDB5420
GeneTree (enSembl)ENSG00000128567
Phylogenetic Trees/Animal Genes : TreeFamPODXL
HOVERGENO00592
HOGENOMO00592
Homologs : HomoloGenePODXL
Homology/Alignments : Family Browser (UCSC)PODXL
Gene fusions - Rearrangements
Fusion : MitelmanATAD2/PODXL [8q24.13/7q32.3]  [t(7;8)(q32;q24)]  
Fusion: TCGAATAD2 8q24.13 PODXL 7q32.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPODXL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PODXL
dbVarPODXL
ClinVarPODXL
1000_GenomesPODXL 
Exome Variant ServerPODXL
ExAC (Exome Aggregation Consortium)PODXL (select the gene name)
Genetic variants : HAPMAP5420
Genomic Variants (DGV)PODXL [DGVbeta]
DECIPHERPODXL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPODXL 
Mutations
ICGC Data PortalPODXL 
TCGA Data PortalPODXL 
Broad Tumor PortalPODXL
OASIS PortalPODXL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPODXL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPODXL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PODXL
DgiDB (Drug Gene Interaction Database)PODXL
DoCM (Curated mutations)PODXL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PODXL (select a term)
intoGenPODXL
Cancer3DPODXL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602632   
Orphanet
MedgenPODXL
Genetic Testing Registry PODXL
NextProtO00592 [Medical]
TSGene5420
GENETestsPODXL
Target ValidationPODXL
Huge Navigator PODXL [HugePedia]
snp3D : Map Gene to Disease5420
BioCentury BCIQPODXL
ClinGenPODXL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5420
Chemical/Pharm GKB GenePA33493
Clinical trialPODXL
Miscellaneous
canSAR (ICR)PODXL (select the gene name)
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePODXL
EVEXPODXL
GoPubMedPODXL
iHOPPODXL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:10 CEST 2017

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