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POLD4 (DNA polymerase delta 4, accessory subunit)

Identity

Alias_namespolymerase (DNA-directed), delta 4, accessory subunit
polymerase (DNA) delta 4, accessory subunit
Alias_symbol (synonym)p12
POLDS
Other alias
HGNC (Hugo) POLD4
LocusID (NCBI) 57804
Atlas_Id 43417
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67350765 and ends at 67353596 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADRBK1 (11q13.2) / POLD4 (11q13.2)BCAS3 (17q23.2) / POLD4 (11q13.2)THAP12 (11q13.5) / POLD4 (11q13.2)
ADRBK1 11q13.2 / POLD4 11q13.2BCAS3 17q23.2 / POLD4 11q13.2PRKRIR 11q13.5 / POLD4 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POLD4   14106
Cards
Entrez_Gene (NCBI)POLD4  57804  DNA polymerase delta 4, accessory subunit
AliasesPOLDS; p12
GeneCards (Weizmann)POLD4
Ensembl hg19 (Hinxton)ENSG00000175482 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175482 [Gene_View]  chr11:67350765-67353596 [Contig_View]  POLD4 [Vega]
ICGC DataPortalENSG00000175482
TCGA cBioPortalPOLD4
AceView (NCBI)POLD4
Genatlas (Paris)POLD4
WikiGenes57804
SOURCE (Princeton)POLD4
Genetics Home Reference (NIH)POLD4
Genomic and cartography
GoldenPath hg38 (UCSC)POLD4  -     chr11:67350765-67353596 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLD4  -     11q13.2   [Description]    (hg19-Feb_2009)
EnsemblPOLD4 - 11q13.2 [CytoView hg19]  POLD4 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIPOLD4 [Mapview hg19]  POLD4 [Mapview hg38]
OMIM611525   
Gene and transcription
Genbank (Entrez)AB209274 AF179890 BC001334 BC070250 BG403692
RefSeq transcript (Entrez)NM_001256870 NM_021173
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POLD4
Cluster EST : UnigeneHs.523829 [ NCBI ]
CGAP (NCI)Hs.523829
Alternative Splicing GalleryENSG00000175482
Gene ExpressionPOLD4 [ NCBI-GEO ]   POLD4 [ EBI - ARRAY_EXPRESS ]   POLD4 [ SEEK ]   POLD4 [ MEM ]
Gene Expression Viewer (FireBrowse)POLD4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57804
GTEX Portal (Tissue expression)POLD4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCU8
Splice isoforms : SwissVarQ9HCU8
PhosPhoSitePlusQ9HCU8
Domains : Interpro (EBI)DNA_pol_delta_4   
Domain families : Pfam (Sanger)DNA_pol_delta_4 (PF04081)   
Domain families : Pfam (NCBI)pfam04081   
Conserved Domain (NCBI)POLD4
DMDM Disease mutations57804
Blocks (Seattle)POLD4
SuperfamilyQ9HCU8
Human Protein AtlasENSG00000175482
Peptide AtlasQ9HCU8
HPRD17873
IPIIPI00028152   IPI00976709   IPI01013535   IPI00982981   IPI01014681   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCU8
IntAct (EBI)Q9HCU8
FunCoupENSG00000175482
BioGRIDPOLD4
STRING (EMBL)POLD4
ZODIACPOLD4
Ontologies - Pathways
QuickGOQ9HCU8
Ontology : AmiGOtelomere maintenance via recombination  telomere maintenance  DNA synthesis involved in DNA repair  DNA-directed DNA polymerase activity  DNA-directed DNA polymerase activity  protein binding  nucleus  nucleoplasm  nucleolus  mitochondrion  cytosol  DNA replication  DNA-dependent DNA replication  DNA ligation  transcription-coupled nucleotide-excision repair  nucleotide-excision repair, DNA incision, 5'-to lesion  nucleotide-excision repair, DNA gap filling  mismatch repair  translesion synthesis  nucleotide-excision repair, DNA incision  DNA damage response, detection of DNA damage  delta DNA polymerase complex  
Ontology : EGO-EBItelomere maintenance via recombination  telomere maintenance  DNA synthesis involved in DNA repair  DNA-directed DNA polymerase activity  DNA-directed DNA polymerase activity  protein binding  nucleus  nucleoplasm  nucleolus  mitochondrion  cytosol  DNA replication  DNA-dependent DNA replication  DNA ligation  transcription-coupled nucleotide-excision repair  nucleotide-excision repair, DNA incision, 5'-to lesion  nucleotide-excision repair, DNA gap filling  mismatch repair  translesion synthesis  nucleotide-excision repair, DNA incision  DNA damage response, detection of DNA damage  delta DNA polymerase complex  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    DNA replication    Base excision repair    Nucleotide excision repair    Mismatch repair    Homologous recombination    HTLV-I infection   
NDEx NetworkPOLD4
Atlas of Cancer Signalling NetworkPOLD4
Wikipedia pathwaysPOLD4
Orthology - Evolution
OrthoDB57804
GeneTree (enSembl)ENSG00000175482
Phylogenetic Trees/Animal Genes : TreeFamPOLD4
HOVERGENQ9HCU8
HOGENOMQ9HCU8
Homologs : HomoloGenePOLD4
Homology/Alignments : Family Browser (UCSC)POLD4
Gene fusions - Rearrangements
Fusion : MitelmanADRBK1/POLD4 [11q13.2/11q13.2]  [t(11;11)(q13;q13)]  
Fusion : MitelmanBCAS3/POLD4 [17q23.2/11q13.2]  [t(11;17)(q13;q23)]  
Fusion : MitelmanPRKRIR/POLD4 [11q13.5/11q13.2]  [t(11;11)(q13;q13)]  
Fusion: TCGAADRBK1 11q13.2 POLD4 11q13.2 BRCA
Fusion: TCGABCAS3 17q23.2 POLD4 11q13.2 BRCA
Fusion: TCGAPRKRIR 11q13.5 POLD4 11q13.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLD4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLD4
dbVarPOLD4
ClinVarPOLD4
1000_GenomesPOLD4 
Exome Variant ServerPOLD4
ExAC (Exome Aggregation Consortium)POLD4 (select the gene name)
Genetic variants : HAPMAP57804
Genomic Variants (DGV)POLD4 [DGVbeta]
DECIPHERPOLD4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLD4 
Mutations
ICGC Data PortalPOLD4 
TCGA Data PortalPOLD4 
Broad Tumor PortalPOLD4
OASIS PortalPOLD4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLD4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOLD4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLD4
DgiDB (Drug Gene Interaction Database)POLD4
DoCM (Curated mutations)POLD4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLD4 (select a term)
intoGenPOLD4
Cancer3DPOLD4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611525   
Orphanet
MedgenPOLD4
Genetic Testing Registry POLD4
NextProtQ9HCU8 [Medical]
TSGene57804
GENETestsPOLD4
Target ValidationPOLD4
Huge Navigator POLD4 [HugePedia]
snp3D : Map Gene to Disease57804
BioCentury BCIQPOLD4
ClinGenPOLD4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57804
Chemical/Pharm GKB GenePA33498
Clinical trialPOLD4
Miscellaneous
canSAR (ICR)POLD4 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOLD4
EVEXPOLD4
GoPubMedPOLD4
iHOPPOLD4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:03:49 CEST 2017

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