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POLD4 (DNA polymerase delta 4, accessory subunit)

Identity

Alias (NCBI)POLDS
p12
HGNC (Hugo) POLD4
HGNC Alias symbp12
POLDS
HGNC Alias nameDNA polymerase delta smallest subunit p12
HGNC Previous namepolymerase (DNA-directed), delta 4, accessory subunit
 polymerase (DNA) delta 4, accessory subunit
LocusID (NCBI) 57804
Atlas_Id 43417
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67350773 and ends at 67353546 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADRBK1 (11q13.2) / POLD4 (11q13.2)BCAS3 (17q23.2) / POLD4 (11q13.2)THAP12 (11q13.5) / POLD4 (11q13.2)
ADRBK1 11q13.2 / POLD4 11q13.2BCAS3 17q23.2 / POLD4 11q13.2PRKRIR 11q13.5 / POLD4 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)POLD4   14106
Cards
Entrez_Gene (NCBI)POLD4    DNA polymerase delta 4, accessory subunit
AliasesPOLDS; p12
GeneCards (Weizmann)POLD4
Ensembl hg19 (Hinxton)ENSG00000175482 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175482 [Gene_View]  ENSG00000175482 [Sequence]  chr11:67350773-67353546 [Contig_View]  POLD4 [Vega]
ICGC DataPortalENSG00000175482
TCGA cBioPortalPOLD4
AceView (NCBI)POLD4
Genatlas (Paris)POLD4
SOURCE (Princeton)POLD4
Genetics Home Reference (NIH)POLD4
Genomic and cartography
GoldenPath hg38 (UCSC)POLD4  -     chr11:67350773-67353546 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLD4  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathPOLD4 - 11q13.2 [CytoView hg19]  POLD4 - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000175482
Genome Data Viewer NCBIPOLD4 [Mapview hg19]  
OMIM611525   
Gene and transcription
Genbank (Entrez)AB209274 AF179890 BC001334 BC070250 BG403692
RefSeq transcript (Entrez)NM_001256870 NM_021173
Consensus coding sequences : CCDS (NCBI)POLD4
Gene ExpressionPOLD4 [ NCBI-GEO ]   POLD4 [ EBI - ARRAY_EXPRESS ]   POLD4 [ SEEK ]   POLD4 [ MEM ]
Gene Expression Viewer (FireBrowse)POLD4 [ Firebrowse - Broad ]
GenevisibleExpression of POLD4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57804
GTEX Portal (Tissue expression)POLD4
Human Protein AtlasENSG00000175482-POLD4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCU8
PhosPhoSitePlusQ9HCU8
Domains : Interpro (EBI)DNA_pol_delta_4   
Domain families : Pfam (Sanger)DNA_pol_delta_4 (PF04081)   
Domain families : Pfam (NCBI)pfam04081   
Conserved Domain (NCBI)POLD4
PDB (RSDB)6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
PDB Europe6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
PDB (PDBSum)6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
PDB (IMB)6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
Structural Biology KnowledgeBase6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
SCOP (Structural Classification of Proteins)6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
CATH (Classification of proteins structures)6HVO    6S1M    6S1N    6S1O    6TNY    6TNZ   
SuperfamilyQ9HCU8
AlphaFold pdb e-kbQ9HCU8   
Human Protein Atlas [tissue]ENSG00000175482-POLD4 [tissue]
HPRD17873
Protein Interaction databases
DIP (DOE-UCLA)Q9HCU8
IntAct (EBI)Q9HCU8
BioGRIDPOLD4
STRING (EMBL)POLD4
ZODIACPOLD4
Ontologies - Pathways
QuickGOQ9HCU8
Ontology : AmiGOtelomere maintenance  DNA synthesis involved in DNA repair  DNA-directed DNA polymerase activity  protein binding  nucleoplasm  DNA-dependent DNA replication  transcription-coupled nucleotide-excision repair  base-excision repair, gap-filling  nucleotide-excision repair, DNA incision, 5'-to lesion  nucleotide-excision repair, DNA gap filling  mismatch repair  translesion synthesis  telomere maintenance via semi-conservative replication  nucleotide-excision repair, DNA incision  DNA damage response, detection of DNA damage  delta DNA polymerase complex  
Ontology : EGO-EBItelomere maintenance  DNA synthesis involved in DNA repair  DNA-directed DNA polymerase activity  protein binding  nucleoplasm  DNA-dependent DNA replication  transcription-coupled nucleotide-excision repair  base-excision repair, gap-filling  nucleotide-excision repair, DNA incision, 5'-to lesion  nucleotide-excision repair, DNA gap filling  mismatch repair  translesion synthesis  telomere maintenance via semi-conservative replication  nucleotide-excision repair, DNA incision  DNA damage response, detection of DNA damage  delta DNA polymerase complex  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    DNA replication    Base excision repair    Nucleotide excision repair    Mismatch repair    Homologous recombination    HTLV-I infection   
NDEx NetworkPOLD4
Atlas of Cancer Signalling NetworkPOLD4
Wikipedia pathwaysPOLD4
Orthology - Evolution
OrthoDB57804
GeneTree (enSembl)ENSG00000175482
Phylogenetic Trees/Animal Genes : TreeFamPOLD4
Homologs : HomoloGenePOLD4
Homology/Alignments : Family Browser (UCSC)POLD4
Gene fusions - Rearrangements
Fusion : MitelmanADRBK1/POLD4 [11q13.2/11q13.2]  
Fusion : MitelmanBCAS3/POLD4 [17q23.2/11q13.2]  
Fusion : MitelmanPRKRIR/POLD4 [11q13.5/11q13.2]  
Fusion : QuiverPOLD4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLD4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLD4
dbVarPOLD4
ClinVarPOLD4
MonarchPOLD4
1000_GenomesPOLD4 
Exome Variant ServerPOLD4
GNOMAD BrowserENSG00000175482
Varsome BrowserPOLD4
ACMGPOLD4 variants
VarityQ9HCU8
Genomic Variants (DGV)POLD4 [DGVbeta]
DECIPHERPOLD4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLD4 
Mutations
ICGC Data PortalPOLD4 
TCGA Data PortalPOLD4 
Broad Tumor PortalPOLD4
OASIS PortalPOLD4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLD4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPOLD4
Mutations and Diseases : HGMDPOLD4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPOLD4
DgiDB (Drug Gene Interaction Database)POLD4
DoCM (Curated mutations)POLD4
CIViC (Clinical Interpretations of Variants in Cancer)POLD4
Cancer3DPOLD4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611525   
Orphanet
DisGeNETPOLD4
MedgenPOLD4
Genetic Testing Registry POLD4
NextProtQ9HCU8 [Medical]
GENETestsPOLD4
Target ValidationPOLD4
Huge Navigator POLD4 [HugePedia]
ClinGenPOLD4
Clinical trials, drugs, therapy
MyCancerGenomePOLD4
Protein Interactions : CTDPOLD4
Pharm GKB GenePA33498
PharosQ9HCU8
Clinical trialPOLD4
Miscellaneous
canSAR (ICR)POLD4
HarmonizomePOLD4
DataMed IndexPOLD4
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPOLD4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:26:02 CEST 2021

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