POLDIP2 (DNA polymerase delta interacting protein 2)

2003-10-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
PDIP38,POLD4,p38
FUSION GENES

Other Information

Locus ID:

NCBI: 26073
MIM: 611519
HGNC: 23781
Ensembl: ENSG00000004142

Variants:

dbSNP: 26073
ClinVar: 26073
TCGA: ENSG00000004142
COSMIC: POLDIP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000004142ENST00000540200Q9Y2S7
ENSG00000004142ENST00000618887B4DEM9

Expression (GTEx)

0
50
100
150
200
250

References

Pubmed IDYearTitleCitations
195745522009Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells.190
164282952005PDIP38 associates with proteins constituting the mitochondrial DNA nucleoid.30
205542542010Crosstalk between replicative and translesional DNA polymerases: PDIP38 interacts directly with Poleta.25
158118542005Further characterization of human DNA polymerase delta interacting protein 38.21
241910252013DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass.21
269845272016PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities.18
201588802010Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression.17
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
176236712007The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38.14
239896112013PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2.13

Citation

Dessen P

POLDIP2 (DNA polymerase delta interacting protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/41772/poldip2