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POLR2G (RNA polymerase II subunit G)

Identity

Alias_namespolymerase (RNA) II (DNA directed) polypeptide G
Alias_symbol (synonym)hRPB19
hsRPB7
RPB7
Other aliasRPB19
HGNC (Hugo) POLR2G
LocusID (NCBI) 5436
Atlas_Id 41782
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62761539 and ends at 62766715 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC3A2 (11q12.3) / POLR2G (11q12.3)SMAP1 (6q13) / POLR2G (11q12.3)SLC3A2 11q12.3 / POLR2G 11q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POLR2G   9194
Cards
Entrez_Gene (NCBI)POLR2G  5436  RNA polymerase II subunit G
AliasesRPB19; RPB7; hRPB19; hsRPB7
GeneCards (Weizmann)POLR2G
Ensembl hg19 (Hinxton)ENSG00000168002 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168002 [Gene_View]  chr11:62761539-62766715 [Contig_View]  POLR2G [Vega]
ICGC DataPortalENSG00000168002
TCGA cBioPortalPOLR2G
AceView (NCBI)POLR2G
Genatlas (Paris)POLR2G
WikiGenes5436
SOURCE (Princeton)POLR2G
Genetics Home Reference (NIH)POLR2G
Genomic and cartography
GoldenPath hg38 (UCSC)POLR2G  -     chr11:62761539-62766715 +  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLR2G  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblPOLR2G - 11q12.3 [CytoView hg19]  POLR2G - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBIPOLR2G [Mapview hg19]  POLR2G [Mapview hg38]
OMIM602013   
Gene and transcription
Genbank (Entrez)AK312131 AW016747 BC112162 BC112164 BG530809
RefSeq transcript (Entrez)NM_002696
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POLR2G
Cluster EST : UnigeneHs.14839 [ NCBI ]
CGAP (NCI)Hs.14839
Alternative Splicing GalleryENSG00000168002
Gene ExpressionPOLR2G [ NCBI-GEO ]   POLR2G [ EBI - ARRAY_EXPRESS ]   POLR2G [ SEEK ]   POLR2G [ MEM ]
Gene Expression Viewer (FireBrowse)POLR2G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5436
GTEX Portal (Tissue expression)POLR2G
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62487   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62487  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62487
Splice isoforms : SwissVarP62487
PhosPhoSitePlusP62487
Domains : Interpro (EBI)NA-bd_OB-fold    RNA_pol_Rpb7_N    S1_dom    S1_domain   
Domain families : Pfam (Sanger)S1 (PF00575)    SHS2_Rpb7-N (PF03876)   
Domain families : Pfam (NCBI)pfam00575    pfam03876   
Domain families : Smart (EMBL)S1 (SM00316)  
Conserved Domain (NCBI)POLR2G
DMDM Disease mutations5436
Blocks (Seattle)POLR2G
PDB (SRS)2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
PDB (PDBSum)2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
PDB (IMB)2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
PDB (RSDB)2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
Structural Biology KnowledgeBase2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
SCOP (Structural Classification of Proteins)2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
CATH (Classification of proteins structures)2C35    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD   
SuperfamilyP62487
Human Protein AtlasENSG00000168002
Peptide AtlasP62487
HPRD15995
IPIIPI00218895   IPI00984239   IPI00983669   IPI00977348   IPI00984784   
Protein Interaction databases
DIP (DOE-UCLA)P62487
IntAct (EBI)P62487
FunCoupENSG00000168002
BioGRIDPOLR2G
STRING (EMBL)POLR2G
ZODIACPOLR2G
Ontologies - Pathways
QuickGOP62487
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, exonucleolytic  mRNA splicing, via spliceosome  P-body  single-stranded DNA binding  single-stranded RNA binding  DNA-directed 5'-3' RNA polymerase activity  nucleus  nucleoplasm  nucleoplasm  DNA-directed RNA polymerase II, core complex  transcription-coupled nucleotide-excision repair  transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  7-methylguanosine mRNA capping  apoptotic process  fibroblast growth factor receptor signaling pathway  gene expression  gene silencing by RNA  translation initiation factor binding  somatic stem cell population maintenance  snRNA transcription from RNA polymerase II promoter  positive regulation of translational initiation  positive regulation of viral transcription  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, exonucleolytic  mRNA splicing, via spliceosome  P-body  single-stranded DNA binding  single-stranded RNA binding  DNA-directed 5'-3' RNA polymerase activity  nucleus  nucleoplasm  nucleoplasm  DNA-directed RNA polymerase II, core complex  transcription-coupled nucleotide-excision repair  transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  7-methylguanosine mRNA capping  apoptotic process  fibroblast growth factor receptor signaling pathway  gene expression  gene silencing by RNA  translation initiation factor binding  somatic stem cell population maintenance  snRNA transcription from RNA polymerase II promoter  positive regulation of translational initiation  positive regulation of viral transcription  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    RNA polymerase    Huntington's disease    Epstein-Barr virus infection   
NDEx NetworkPOLR2G
Atlas of Cancer Signalling NetworkPOLR2G
Wikipedia pathwaysPOLR2G
Orthology - Evolution
OrthoDB5436
GeneTree (enSembl)ENSG00000168002
Phylogenetic Trees/Animal Genes : TreeFamPOLR2G
HOVERGENP62487
HOGENOMP62487
Homologs : HomoloGenePOLR2G
Homology/Alignments : Family Browser (UCSC)POLR2G
Gene fusions - Rearrangements
Fusion : MitelmanSLC3A2/POLR2G [11q12.3/11q12.3]  [t(11;11)(q12;q12)]  
Fusion: TCGASLC3A2 11q12.3 POLR2G 11q12.3 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLR2G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLR2G
dbVarPOLR2G
ClinVarPOLR2G
1000_GenomesPOLR2G 
Exome Variant ServerPOLR2G
ExAC (Exome Aggregation Consortium)POLR2G (select the gene name)
Genetic variants : HAPMAP5436
Genomic Variants (DGV)POLR2G [DGVbeta]
DECIPHERPOLR2G [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLR2G 
Mutations
ICGC Data PortalPOLR2G 
TCGA Data PortalPOLR2G 
Broad Tumor PortalPOLR2G
OASIS PortalPOLR2G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLR2G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOLR2G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLR2G
DgiDB (Drug Gene Interaction Database)POLR2G
DoCM (Curated mutations)POLR2G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLR2G (select a term)
intoGenPOLR2G
Cancer3DPOLR2G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602013   
Orphanet
MedgenPOLR2G
Genetic Testing Registry POLR2G
NextProtP62487 [Medical]
TSGene5436
GENETestsPOLR2G
Target ValidationPOLR2G
Huge Navigator POLR2G [HugePedia]
snp3D : Map Gene to Disease5436
BioCentury BCIQPOLR2G
ClinGenPOLR2G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5436
Chemical/Pharm GKB GenePA33514
Clinical trialPOLR2G
Miscellaneous
canSAR (ICR)POLR2G (select the gene name)
Probes
Litterature
PubMed125 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOLR2G
EVEXPOLR2G
GoPubMedPOLR2G
iHOPPOLR2G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:17 CEST 2017

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