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POLR2J2 (RNA polymerase II subunit J2)

Identity

Alias_namespolymerase (RNA) II (DNA directed) polypeptide J2
Alias_symbol (synonym)RPB11b1
Other aliasHRPB11B
HGNC (Hugo) POLR2J2
LocusID (NCBI) 246721
Atlas_Id 72051
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 102636748 and ends at 102671729 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POLR2J2   23208
Cards
Entrez_Gene (NCBI)POLR2J2  246721  RNA polymerase II subunit J2
AliasesHRPB11B; RPB11b1
GeneCards (Weizmann)POLR2J2
Ensembl hg19 (Hinxton)ENSG00000267645 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000267645 [Gene_View]  chr7:102636748-102671729 [Contig_View]  POLR2J2 [Vega]
ICGC DataPortalENSG00000267645
TCGA cBioPortalPOLR2J2
AceView (NCBI)POLR2J2
Genatlas (Paris)POLR2J2
WikiGenes246721
SOURCE (Princeton)POLR2J2
Genetics Home Reference (NIH)POLR2J2
Genomic and cartography
GoldenPath hg38 (UCSC)POLR2J2  -     chr7:102636748-102671729 -  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLR2J2  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblPOLR2J2 - 7q22.1 [CytoView hg19]  POLR2J2 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBIPOLR2J2 [Mapview hg19]  POLR2J2 [Mapview hg38]
OMIM609881   
Gene and transcription
Genbank (Entrez)AB209398 AI073388 AJ277739 BC050598 BC056864
RefSeq transcript (Entrez)NM_032958 NM_032959 NM_145325
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POLR2J2
Cluster EST : UnigeneHs.732239 [ NCBI ]
CGAP (NCI)Hs.732239
Alternative Splicing GalleryENSG00000267645
Gene ExpressionPOLR2J2 [ NCBI-GEO ]   POLR2J2 [ EBI - ARRAY_EXPRESS ]   POLR2J2 [ SEEK ]   POLR2J2 [ MEM ]
Gene Expression Viewer (FireBrowse)POLR2J2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246721
GTEX Portal (Tissue expression)POLR2J2
Human Protein AtlasENSG00000267645-POLR2J2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZM3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZM3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZM3
Splice isoforms : SwissVarQ9GZM3
PhosPhoSitePlusQ9GZM3
Domaine pattern : Prosite (Expaxy)RNA_POL_L_13KD (PS01154)   
Domains : Interpro (EBI)RBP11-like_dimer    RNA_pol_Rpb11_13-16kDa_CS   
Domain families : Pfam (Sanger)RNA_pol_L_2 (PF13656)   
Domain families : Pfam (NCBI)pfam13656   
Conserved Domain (NCBI)POLR2J2
DMDM Disease mutations246721
Blocks (Seattle)POLR2J2
SuperfamilyQ9GZM3
Human Protein Atlas [tissue]ENSG00000267645-POLR2J2 [tissue]
Peptide AtlasQ9GZM3
HPRD17878
IPIIPI00884938   IPI00016841   IPI00854665   IPI00983105   IPI00945319   IPI00935876   IPI00966714   IPI00967483   IPI00879159   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZM3
IntAct (EBI)Q9GZM3
FunCoupENSG00000267645
BioGRIDPOLR2J2
STRING (EMBL)POLR2J2
ZODIACPOLR2J2
Ontologies - Pathways
QuickGOQ9GZM3
Ontology : AmiGORNA polymerase II activity  DNA binding  DNA-directed RNA polymerase II, core complex  transcription from RNA polymerase II promoter  protein dimerization activity  
Ontology : EGO-EBIRNA polymerase II activity  DNA binding  DNA-directed RNA polymerase II, core complex  transcription from RNA polymerase II promoter  protein dimerization activity  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    RNA polymerase    Huntington's disease    Epstein-Barr virus infection   
NDEx NetworkPOLR2J2
Atlas of Cancer Signalling NetworkPOLR2J2
Wikipedia pathwaysPOLR2J2
Orthology - Evolution
OrthoDB246721
GeneTree (enSembl)ENSG00000267645
Phylogenetic Trees/Animal Genes : TreeFamPOLR2J2
HOVERGENQ9GZM3
HOGENOMQ9GZM3
Homologs : HomoloGenePOLR2J2
Homology/Alignments : Family Browser (UCSC)POLR2J2
Gene fusions - Rearrangements
Tumor Fusion PortalPOLR2J2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLR2J2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLR2J2
dbVarPOLR2J2
ClinVarPOLR2J2
1000_GenomesPOLR2J2 
Exome Variant ServerPOLR2J2
ExAC (Exome Aggregation Consortium)ENSG00000267645
GNOMAD BrowserENSG00000267645
Genetic variants : HAPMAP246721
Genomic Variants (DGV)POLR2J2 [DGVbeta]
DECIPHERPOLR2J2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLR2J2 
Mutations
ICGC Data PortalPOLR2J2 
TCGA Data PortalPOLR2J2 
Broad Tumor PortalPOLR2J2
OASIS PortalPOLR2J2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLR2J2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOLR2J2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLR2J2
DgiDB (Drug Gene Interaction Database)POLR2J2
DoCM (Curated mutations)POLR2J2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLR2J2 (select a term)
intoGenPOLR2J2
Cancer3DPOLR2J2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609881   
Orphanet
DisGeNETPOLR2J2
MedgenPOLR2J2
Genetic Testing Registry POLR2J2
NextProtQ9GZM3 [Medical]
TSGene246721
GENETestsPOLR2J2
Target ValidationPOLR2J2
Huge Navigator POLR2J2 [HugePedia]
snp3D : Map Gene to Disease246721
BioCentury BCIQPOLR2J2
ClinGenPOLR2J2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD246721
Chemical/Pharm GKB GenePA164724655
Clinical trialPOLR2J2
Miscellaneous
canSAR (ICR)POLR2J2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOLR2J2
EVEXPOLR2J2
GoPubMedPOLR2J2
iHOPPOLR2J2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:16:58 CET 2017

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