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POLR2J3 (RNA polymerase II subunit J3)

Identity

Alias_namespolymerase (RNA) II (DNA directed) polypeptide J3
Other aliasPOLR2J2
RPB11b1
RPB11b2
HGNC (Hugo) POLR2J3
LocusID (NCBI) 548644
Atlas_Id 72052
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 102537919 and ends at 102572621 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POLR2J3   33853
Cards
Entrez_Gene (NCBI)POLR2J3  548644  RNA polymerase II subunit J3
AliasesPOLR2J2; RPB11b1; RPB11b2
GeneCards (Weizmann)POLR2J3
Ensembl hg19 (Hinxton)ENSG00000168255 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168255 [Gene_View]  chr7:102537919-102572621 [Contig_View]  POLR2J3 [Vega]
ICGC DataPortalENSG00000168255
TCGA cBioPortalPOLR2J3
AceView (NCBI)POLR2J3
Genatlas (Paris)POLR2J3
WikiGenes548644
SOURCE (Princeton)POLR2J3
Genetics Home Reference (NIH)POLR2J3
Genomic and cartography
GoldenPath hg38 (UCSC)POLR2J3  -     chr7:102537919-102572621 -  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLR2J3  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblPOLR2J3 - 7q22.1 [CytoView hg19]  POLR2J3 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBIPOLR2J3 [Mapview hg19]  POLR2J3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF468111 AJ277740 AJ277741 AK309487 BC044209
RefSeq transcript (Entrez)NM_001015884 NM_001097615
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POLR2J3
Cluster EST : UnigeneHs.656696 [ NCBI ]
CGAP (NCI)Hs.656696
Alternative Splicing GalleryENSG00000168255
Gene ExpressionPOLR2J3 [ NCBI-GEO ]   POLR2J3 [ EBI - ARRAY_EXPRESS ]   POLR2J3 [ SEEK ]   POLR2J3 [ MEM ]
Gene Expression Viewer (FireBrowse)POLR2J3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)548644
GTEX Portal (Tissue expression)POLR2J3
Human Protein AtlasENSG00000168255-POLR2J3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1A7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1A7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1A7
Splice isoforms : SwissVarQ9H1A7
PhosPhoSitePlusQ9H1A7
Domaine pattern : Prosite (Expaxy)RNA_POL_L_13KD (PS01154)   
Domains : Interpro (EBI)RBP11-like_dimer    RNA_pol_Rpb11_13-16kDa_CS   
Domain families : Pfam (Sanger)RNA_pol_L_2 (PF13656)   
Domain families : Pfam (NCBI)pfam13656   
Conserved Domain (NCBI)POLR2J3
DMDM Disease mutations548644
Blocks (Seattle)POLR2J3
SuperfamilyQ9H1A7
Human Protein Atlas [tissue]ENSG00000168255-POLR2J3 [tissue]
Peptide AtlasQ9H1A7
HPRD18684
IPIIPI00556199   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1A7
IntAct (EBI)Q9H1A7
FunCoupENSG00000168255
BioGRIDPOLR2J3
STRING (EMBL)POLR2J3
ZODIACPOLR2J3
Ontologies - Pathways
QuickGOQ9H1A7
Ontology : AmiGORNA polymerase II activity  DNA binding  DNA-directed RNA polymerase II, core complex  transcription from RNA polymerase II promoter  protein dimerization activity  
Ontology : EGO-EBIRNA polymerase II activity  DNA binding  DNA-directed RNA polymerase II, core complex  transcription from RNA polymerase II promoter  protein dimerization activity  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    RNA polymerase    Huntington's disease    Epstein-Barr virus infection   
NDEx NetworkPOLR2J3
Atlas of Cancer Signalling NetworkPOLR2J3
Wikipedia pathwaysPOLR2J3
Orthology - Evolution
OrthoDB548644
GeneTree (enSembl)ENSG00000168255
Phylogenetic Trees/Animal Genes : TreeFamPOLR2J3
HOVERGENQ9H1A7
HOGENOMQ9H1A7
Homologs : HomoloGenePOLR2J3
Homology/Alignments : Family Browser (UCSC)POLR2J3
Gene fusions - Rearrangements
Fusion: Tumor Portal POLR2J3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLR2J3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLR2J3
dbVarPOLR2J3
ClinVarPOLR2J3
1000_GenomesPOLR2J3 
Exome Variant ServerPOLR2J3
ExAC (Exome Aggregation Consortium)ENSG00000168255
GNOMAD BrowserENSG00000168255
Genetic variants : HAPMAP548644
Genomic Variants (DGV)POLR2J3 [DGVbeta]
DECIPHERPOLR2J3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLR2J3 
Mutations
ICGC Data PortalPOLR2J3 
TCGA Data PortalPOLR2J3 
Broad Tumor PortalPOLR2J3
OASIS PortalPOLR2J3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLR2J3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOLR2J3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLR2J3
DgiDB (Drug Gene Interaction Database)POLR2J3
DoCM (Curated mutations)POLR2J3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLR2J3 (select a term)
intoGenPOLR2J3
Cancer3DPOLR2J3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPOLR2J3
Genetic Testing Registry POLR2J3
NextProtQ9H1A7 [Medical]
TSGene548644
GENETestsPOLR2J3
Target ValidationPOLR2J3
Huge Navigator POLR2J3 [HugePedia]
snp3D : Map Gene to Disease548644
BioCentury BCIQPOLR2J3
ClinGenPOLR2J3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD548644
Chemical/Pharm GKB GenePA164724678
Clinical trialPOLR2J3
Miscellaneous
canSAR (ICR)POLR2J3 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOLR2J3
EVEXPOLR2J3
GoPubMedPOLR2J3
iHOPPOLR2J3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:23:03 CET 2017

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