Atlas of Genetics and Cytogenetics in Oncology and Haematology

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POLR3D (RNA polymerase III subunit D)

Identity

Alias (NCBI)BN51T
C53
RPC4
RPC53
TSBN51
HGNC (Hugo) POLR3D
HGNC Alias symbTSBN51
RPC4
HGNC Previous nameBN51T
HGNC Previous nameBN51 (BHK21) temperature sensitivity complementing
 polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
LocusID (NCBI) 661
Atlas_Id 41783
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 22245133 and ends at 22254601 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)POLR3D   1080
Cards
Entrez_Gene (NCBI)POLR3D    RNA polymerase III subunit D
AliasesBN51T; C53; RPC4; RPC53; 
TSBN51
GeneCards (Weizmann)POLR3D
Ensembl hg19 (Hinxton)ENSG00000168495 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168495 [Gene_View]  ENSG00000168495 [Sequence]  chr8:22245133-22254601 [Contig_View]  POLR3D [Vega]
ICGC DataPortalENSG00000168495
TCGA cBioPortalPOLR3D
AceView (NCBI)POLR3D
Genatlas (Paris)POLR3D
SOURCE (Princeton)POLR3D
Genetics Home Reference (NIH)POLR3D
Genomic and cartography
GoldenPath hg38 (UCSC)POLR3D  -     chr8:22245133-22254601 +  8p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLR3D  -     8p21.3   [Description]    (hg19-Feb_2009)
GoldenPathPOLR3D - 8p21.3 [CytoView hg19]  POLR3D - 8p21.3 [CytoView hg38]
ImmunoBaseENSG00000168495
genome Data Viewer NCBIPOLR3D [Mapview hg19]  
OMIM187280   
Gene and transcription
Genbank (Entrez)AF346574 AK026588 AK125346 AK295725 AY092086
RefSeq transcript (Entrez)NM_001722
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POLR3D
Alternative Splicing GalleryENSG00000168495
Gene ExpressionPOLR3D [ NCBI-GEO ]   POLR3D [ EBI - ARRAY_EXPRESS ]   POLR3D [ SEEK ]   POLR3D [ MEM ]
Gene Expression Viewer (FireBrowse)POLR3D [ Firebrowse - Broad ]
GenevisibleExpression of POLR3D in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)661
GTEX Portal (Tissue expression)POLR3D
Human Protein AtlasENSG00000168495-POLR3D [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05423   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05423  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05423
Splice isoforms : SwissVarP05423
PhosPhoSitePlusP05423
Domains : Interpro (EBI)RPC4   
Domain families : Pfam (Sanger)RNA_pol_Rpc4 (PF05132)   
Domain families : Pfam (NCBI)pfam05132   
Conserved Domain (NCBI)POLR3D
Blocks (Seattle)POLR3D
SuperfamilyP05423
Human Protein Atlas [tissue]ENSG00000168495-POLR3D [tissue]
Peptide AtlasP05423
HPRD01755
IPIIPI00215978   IPI00982006   IPI00982571   
Protein Interaction databases
DIP (DOE-UCLA)P05423
IntAct (EBI)P05423
BioGRIDPOLR3D
STRING (EMBL)POLR3D
ZODIACPOLR3D
Ontologies - Pathways
QuickGOP05423
Ontology : AmiGOnuclear chromatin  DNA binding  chromatin binding  DNA-directed 5'-3' RNA polymerase activity  nucleoplasm  nucleoplasm  RNA polymerase III complex  RNA polymerase III complex  cytosol  cytosol  transcription by RNA polymerase III  nuclear speck  positive regulation of type I interferon production  positive regulation of interferon-beta production  innate immune response  positive regulation of innate immune response  defense response to virus  
Ontology : EGO-EBInuclear chromatin  DNA binding  chromatin binding  DNA-directed 5'-3' RNA polymerase activity  nucleoplasm  nucleoplasm  RNA polymerase III complex  RNA polymerase III complex  cytosol  cytosol  transcription by RNA polymerase III  nuclear speck  positive regulation of type I interferon production  positive regulation of interferon-beta production  innate immune response  positive regulation of innate immune response  defense response to virus  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    RNA polymerase    Cytosolic DNA-sensing pathway    Epstein-Barr virus infection   
NDEx NetworkPOLR3D
Atlas of Cancer Signalling NetworkPOLR3D
Wikipedia pathwaysPOLR3D
Orthology - Evolution
OrthoDB661
GeneTree (enSembl)ENSG00000168495
Phylogenetic Trees/Animal Genes : TreeFamPOLR3D
HOGENOMP05423
Homologs : HomoloGenePOLR3D
Homology/Alignments : Family Browser (UCSC)POLR3D
Gene fusions - Rearrangements
Fusion : QuiverPOLR3D
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLR3D [hg38]
dbVarPOLR3D
ClinVarPOLR3D
MonarchPOLR3D
1000_GenomesPOLR3D 
Exome Variant ServerPOLR3D
GNOMAD BrowserENSG00000168495
Varsome BrowserPOLR3D
Genomic Variants (DGV)POLR3D [DGVbeta]
DECIPHERPOLR3D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLR3D 
Mutations
ICGC Data PortalPOLR3D 
TCGA Data PortalPOLR3D 
Broad Tumor PortalPOLR3D
OASIS PortalPOLR3D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLR3D  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPOLR3D
Mutations and Diseases : HGMDPOLR3D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLR3D
DgiDB (Drug Gene Interaction Database)POLR3D
DoCM (Curated mutations)POLR3D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLR3D (select a term)
intoGenPOLR3D
Cancer3DPOLR3D(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM187280   
Orphanet
DisGeNETPOLR3D
MedgenPOLR3D
Genetic Testing Registry POLR3D
NextProtP05423 [Medical]
GENETestsPOLR3D
Target ValidationPOLR3D
Huge Navigator POLR3D [HugePedia]
ClinGenPOLR3D
Clinical trials, drugs, therapy
MyCancerGenomePOLR3D
Protein Interactions : CTD
Pharm GKB GenePA25390
PharosP05423
Clinical trialPOLR3D
Miscellaneous
canSAR (ICR)POLR3D (select the gene name)
HarmonizomePOLR3D
DataMed IndexPOLR3D
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPOLR3D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:32:15 CET 2021
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