POLR3E (RNA polymerase III subunit E)

2014-11-01  

Identity

HGNC
LOCATION
16p12.2
LOCUSID
ALIAS
C37,RPC5,SIN
FUSION GENES

Other Information

Locus ID:

NCBI: 55718
MIM: 617815
HGNC: 30347
Ensembl: ENSG00000058600

Variants:

dbSNP: 55718
ClinVar: 55718
TCGA: ENSG00000058600
COSMIC: POLR3E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000058600ENST00000299853Q9NVU0
ENSG00000058600ENST00000359210Q9NVU0
ENSG00000058600ENST00000418581Q9NVU0
ENSG00000058600ENST00000561494H3BSM3
ENSG00000058600ENST00000563024H3BRY1
ENSG00000058600ENST00000564209Q9NVU0
ENSG00000058600ENST00000564750H3BS41
ENSG00000058600ENST00000564883H3BSI5
ENSG00000058600ENST00000565358H3BMR4
ENSG00000058600ENST00000565551H3BM46
ENSG00000058600ENST00000569757H3BNJ0
ENSG00000058600ENST00000615879A0A0C4DH01

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
RNA polymeraseKEGGko03020
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
RNA polymeraseKEGGhsa03020
Cytosolic DNA-sensing pathwayKEGGko04623
Cytosolic DNA-sensing pathwayKEGGhsa04623
RNA polymerase III, eukaryotesKEGGhsa_M00181
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
RNA polymerase III, eukaryotesKEGGM00181
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Cytosolic sensors of pathogen-associated DNAREACTOMER-HSA-1834949
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase III TranscriptionREACTOMER-HSA-74158
RNA Polymerase III Abortive And Retractive InitiationREACTOMER-HSA-749476
RNA Polymerase III Transcription InitiationREACTOMER-HSA-76046
RNA Polymerase III Transcription Initiation From Type 1 PromoterREACTOMER-HSA-76061
RNA Polymerase III Transcription Initiation From Type 2 PromoterREACTOMER-HSA-76066
RNA Polymerase III Transcription Initiation From Type 3 PromoterREACTOMER-HSA-76071
RNA Polymerase III Chain ElongationREACTOMER-HSA-73780
RNA Polymerase III Transcription TerminationREACTOMER-HSA-73980

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
123911702002Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits.32
297286102019Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection.10

Citation

Dessen P

POLR3E (RNA polymerase III subunit E)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72057/polr3e