POLR3H (RNA polymerase III subunit H)

2014-11-01  

Identity

HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
C25,RPC22.9,RPC8
FUSION GENES

Other Information

Locus ID:

NCBI: 171568
HGNC: 30349
Ensembl: ENSG00000100413

Variants:

dbSNP: 171568
ClinVar: 171568
TCGA: ENSG00000100413
COSMIC: POLR3H

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100413ENST00000337566Q9Y535
ENSG00000100413ENST00000355209Q9Y535
ENSG00000100413ENST00000355209A0A024R1P3
ENSG00000100413ENST00000396504Q9Y535
ENSG00000100413ENST00000396504A0A024R1P3
ENSG00000100413ENST00000407461Q9Y535
ENSG00000100413ENST00000407461A0A024R1P3
ENSG00000100413ENST00000431534F8WDV1
ENSG00000100413ENST00000432789F8WDS5
ENSG00000100413ENST00000442616E7ERZ2

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
RNA polymeraseKEGGko03020
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
RNA polymeraseKEGGhsa03020
Cytosolic DNA-sensing pathwayKEGGko04623
Cytosolic DNA-sensing pathwayKEGGhsa04623
Metabolic pathwaysKEGGhsa01100
RNA polymerase III, eukaryotesKEGGhsa_M00181
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
RNA polymerase III, eukaryotesKEGGM00181
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Cytosolic sensors of pathogen-associated DNAREACTOMER-HSA-1834949
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase III TranscriptionREACTOMER-HSA-74158
RNA Polymerase III Abortive And Retractive InitiationREACTOMER-HSA-749476
RNA Polymerase III Transcription InitiationREACTOMER-HSA-76046
RNA Polymerase III Transcription Initiation From Type 1 PromoterREACTOMER-HSA-76061
RNA Polymerase III Transcription Initiation From Type 2 PromoterREACTOMER-HSA-76066
RNA Polymerase III Transcription Initiation From Type 3 PromoterREACTOMER-HSA-76071
RNA Polymerase III Chain ElongationREACTOMER-HSA-73780
RNA Polymerase III Transcription TerminationREACTOMER-HSA-73980

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192460672009The hepatitis delta virus RNA genome interacts with the human RNA polymerases I and III.14
208433072010Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors.11
308302152019Exome Sequencing Reveals the POLR3H Gene as a Novel Cause of Primary Ovarian Insufficiency.4

Citation

Dessen P

POLR3H (RNA polymerase III subunit H)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72061/polr3h