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POLR3K (polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa)

Identity

Alias_namespolymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
Alias_symbol (synonym)RPC11
Other aliasC11
C11-RNP3
My010
RPC10
RPC12.5
HGNC (Hugo) POLR3K
LocusID (NCBI) 51728
Atlas_Id 72062
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 96979 and ends at 103632 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
POLR3K (16p13.3) / BLOC1S1 (12q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POLR3K   14121
Cards
Entrez_Gene (NCBI)POLR3K  51728  polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
AliasesC11; C11-RNP3; My010; RPC10; 
RPC11; RPC12.5
GeneCards (Weizmann)POLR3K
Ensembl hg19 (Hinxton) [Gene_View]  chr16:96979-103632 [Contig_View]  POLR3K [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr16:96979-103632 [Contig_View]  POLR3K [Vega]
TCGA cBioPortalPOLR3K
AceView (NCBI)POLR3K
Genatlas (Paris)POLR3K
WikiGenes51728
SOURCE (Princeton)POLR3K
Genetics Home Reference (NIH)POLR3K
Genomic and cartography
GoldenPath hg19 (UCSC)POLR3K  -     chr16:96979-103632 -  16p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)POLR3K  -     16p13.3   [Description]    (hg38-Dec_2013)
EnsemblPOLR3K - 16p13.3 [CytoView hg19]  POLR3K - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIPOLR3K [Mapview hg19]  POLR3K [Mapview hg38]
OMIM606007   
Gene and transcription
Genbank (Entrez)AF051316 AF060223 BC011932 DQ896281 DR978472
RefSeq transcript (Entrez)NM_016310
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)POLR3K
Cluster EST : UnigeneHs.632223 [ NCBI ]
CGAP (NCI)Hs.632223
Gene ExpressionPOLR3K [ NCBI-GEO ]   POLR3K [ EBI - ARRAY_EXPRESS ]   POLR3K [ SEEK ]   POLR3K [ MEM ]
Gene Expression Viewer (FireBrowse)POLR3K [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51728
GTEX Portal (Tissue expression)POLR3K
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2Y1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2Y1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2Y1
Splice isoforms : SwissVarQ9Y2Y1
PhosPhoSitePlusQ9Y2Y1
Domaine pattern : Prosite (Expaxy)RNA_POL_M_15KD (PS01030)    ZF_TFIIS_1 (PS00466)    ZF_TFIIS_2 (PS51133)   
Domains : Interpro (EBI)DNA-dir_RNA_pol-M_15_CS    DNA-dir_RNA_pol_M/15kDasu    DNA-dir_RNApol_C11    Znf_TFIIS   
Domain families : Pfam (Sanger)RNA_POL_M_15KD (PF02150)    TFIIS_C (PF01096)   
Domain families : Pfam (NCBI)pfam02150    pfam01096   
Domain families : Smart (EMBL)RPOL9 (SM00661)  ZnF_C2C2 (SM00440)  
Conserved Domain (NCBI)POLR3K
DMDM Disease mutations51728
Blocks (Seattle)POLR3K
SuperfamilyQ9Y2Y1
Peptide AtlasQ9Y2Y1
HPRD16187
IPIIPI00008461   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2Y1
IntAct (EBI)Q9Y2Y1
BioGRIDPOLR3K
STRING (EMBL)POLR3K
ZODIACPOLR3K
Ontologies - Pathways
QuickGOQ9Y2Y1
Ontology : AmiGORNA polymerase III activity  DNA binding  DNA-directed RNA polymerase activity  nucleoplasm  DNA-directed RNA polymerase III complex  nucleolus  cytosol  transcription from RNA polymerase III promoter  transcription elongation from RNA polymerase III promoter  termination of RNA polymerase III transcription  termination of RNA polymerase III transcription  zinc ion binding  gene expression  positive regulation of type I interferon production  innate immune response  defense response to virus  
Ontology : EGO-EBIRNA polymerase III activity  DNA binding  DNA-directed RNA polymerase activity  nucleoplasm  DNA-directed RNA polymerase III complex  nucleolus  cytosol  transcription from RNA polymerase III promoter  transcription elongation from RNA polymerase III promoter  termination of RNA polymerase III transcription  termination of RNA polymerase III transcription  zinc ion binding  gene expression  positive regulation of type I interferon production  innate immune response  defense response to virus  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    RNA polymerase    Cytosolic DNA-sensing pathway    Epstein-Barr virus infection   
NDEx NetworkPOLR3K
Atlas of Cancer Signalling NetworkPOLR3K
Wikipedia pathwaysPOLR3K
Orthology - Evolution
OrthoDB51728
Phylogenetic Trees/Animal Genes : TreeFamPOLR3K
HOVERGENQ9Y2Y1
HOGENOMQ9Y2Y1
Homologs : HomoloGenePOLR3K
Homology/Alignments : Family Browser (UCSC)POLR3K
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLR3K [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLR3K
dbVarPOLR3K
ClinVarPOLR3K
1000_GenomesPOLR3K 
Exome Variant ServerPOLR3K
ExAC (Exome Aggregation Consortium)POLR3K (select the gene name)
Genetic variants : HAPMAP51728
Genomic Variants (DGV)POLR3K [DGVbeta]
DECIPHER (Syndromes)16:96979-103632  
CONAN: Copy Number AnalysisPOLR3K 
Mutations
ICGC Data PortalPOLR3K 
TCGA Data PortalPOLR3K 
Broad Tumor PortalPOLR3K
OASIS PortalPOLR3K [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLR3K  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOLR3K
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLR3K
DgiDB (Drug Gene Interaction Database)POLR3K
DoCM (Curated mutations)POLR3K (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLR3K (select a term)
intoGenPOLR3K
Cancer3DPOLR3K(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606007   
Orphanet
MedgenPOLR3K
Genetic Testing Registry POLR3K
NextProtQ9Y2Y1 [Medical]
TSGene51728
GENETestsPOLR3K
Huge Navigator POLR3K [HugePedia]
snp3D : Map Gene to Disease51728
BioCentury BCIQPOLR3K
ClinGenPOLR3K
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51728
Chemical/Pharm GKB GenePA33521
Clinical trialPOLR3K
Miscellaneous
canSAR (ICR)POLR3K (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOLR3K
EVEXPOLR3K
GoPubMedPOLR3K
iHOPPOLR3K
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:10 CET 2017

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