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POM121 (POM121 transmembrane nucleoporin)

Identity

Alias_namesPOM121 membrane glycoprotein (rat)
POM121 membrane glycoprotein
Alias_symbol (synonym)KIAA0618
DKFZP586G1822
DKFZP586P2220
POM121A
Other aliasP145
HGNC (Hugo) POM121
LocusID (NCBI) 9883
Atlas_Id 53034
Location 7q11.23  [Link to chromosome band 7q11]
Location_base_pair Starts at 72879335 and ends at 72951440 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
JA040725 () / POM121 (7q11.23)PAX5 (9p13.2) / POM121 (7q11.23)POM121 (7q11.23) / POM121 (7q11.23)
TAPBPL (12p13.31) / POM121 (7q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Protein

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(7;9)(q11;p12) PAX5/POM121


External links

Nomenclature
HGNC (Hugo)POM121   19702
Cards
Entrez_Gene (NCBI)POM121  9883  POM121 transmembrane nucleoporin
AliasesP145; POM121A
GeneCards (Weizmann)POM121
Ensembl hg19 (Hinxton)ENSG00000196313 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196313 [Gene_View]  chr7:72879335-72951440 [Contig_View]  POM121 [Vega]
ICGC DataPortalENSG00000196313
TCGA cBioPortalPOM121
AceView (NCBI)POM121
Genatlas (Paris)POM121
WikiGenes9883
SOURCE (Princeton)POM121
Genetics Home Reference (NIH)POM121
Genomic and cartography
GoldenPath hg38 (UCSC)POM121  -     chr7:72879335-72951440 +  7q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POM121  -     7q11.23   [Description]    (hg19-Feb_2009)
EnsemblPOM121 - 7q11.23 [CytoView hg19]  POM121 - 7q11.23 [CytoView hg38]
Mapping of homologs : NCBIPOM121 [Mapview hg19]  POM121 [Mapview hg38]
OMIM615753   
Gene and transcription
Genbank (Entrez)AB014518 AB289621 AK001215 AK022555 AK123814
RefSeq transcript (Entrez)NM_001257190 NM_172020
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POM121
Cluster EST : UnigeneHs.737064 [ NCBI ]
CGAP (NCI)Hs.737064
Alternative Splicing GalleryENSG00000196313
Gene ExpressionPOM121 [ NCBI-GEO ]   POM121 [ EBI - ARRAY_EXPRESS ]   POM121 [ SEEK ]   POM121 [ MEM ]
Gene Expression Viewer (FireBrowse)POM121 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9883
GTEX Portal (Tissue expression)POM121
Human Protein AtlasENSG00000196313-POM121 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HA1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HA1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HA1
Splice isoforms : SwissVarQ96HA1
PhosPhoSitePlusQ96HA1
Domains : Interpro (EBI)Nucleoporin    POM121   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)POM121
DMDM Disease mutations9883
Blocks (Seattle)POM121
SuperfamilyQ96HA1
Human Protein Atlas [tissue]ENSG00000196313-POM121 [tissue]
Peptide AtlasQ96HA1
HPRD11448
IPIIPI00902533   IPI00790779   IPI00902621   IPI00172611   
Protein Interaction databases
DIP (DOE-UCLA)Q96HA1
IntAct (EBI)Q96HA1
FunCoupENSG00000196313
BioGRIDPOM121
STRING (EMBL)POM121
ZODIACPOM121
Ontologies - Pathways
QuickGOQ96HA1
Ontology : AmiGOnucleocytoplasmic transporter activity  protein binding  nuclear envelope  nucleoplasm  endoplasmic reticulum membrane  RNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  mitotic nuclear envelope disassembly  nuclear localization sequence binding  regulation of glucose transport  integral component of membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  gene silencing by RNA  nuclear membrane  nuclear pore central transport channel  nuclear pore nuclear basket  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBInucleocytoplasmic transporter activity  protein binding  nuclear envelope  nucleoplasm  endoplasmic reticulum membrane  RNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  mitotic nuclear envelope disassembly  nuclear localization sequence binding  regulation of glucose transport  integral component of membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  gene silencing by RNA  nuclear membrane  nuclear pore central transport channel  nuclear pore nuclear basket  intracellular transport of virus  regulation of cellular response to heat  
Pathways : KEGGRNA transport   
NDEx NetworkPOM121
Atlas of Cancer Signalling NetworkPOM121
Wikipedia pathwaysPOM121
Orthology - Evolution
OrthoDB9883
GeneTree (enSembl)ENSG00000196313
Phylogenetic Trees/Animal Genes : TreeFamPOM121
HOVERGENQ96HA1
HOGENOMQ96HA1
Homologs : HomoloGenePOM121
Homology/Alignments : Family Browser (UCSC)POM121
Gene fusions - Rearrangements
Fusion : MitelmanPAX5/POM121 [9p13.2/7q11.23]  [t(7;9)(q11;p12)]  
Fusion: Tumor Portal POM121
Fusion Cancer (Beijing)JA040725 [POM121]  -  7q11.23 [FUSC000550]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOM121 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POM121
dbVarPOM121
ClinVarPOM121
1000_GenomesPOM121 
Exome Variant ServerPOM121
ExAC (Exome Aggregation Consortium)ENSG00000196313
GNOMAD BrowserENSG00000196313
Genetic variants : HAPMAP9883
Genomic Variants (DGV)POM121 [DGVbeta]
DECIPHERPOM121 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOM121 
Mutations
ICGC Data PortalPOM121 
TCGA Data PortalPOM121 
Broad Tumor PortalPOM121
OASIS PortalPOM121 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOM121  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOM121
intOGen PortalPOM121
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POM121
DgiDB (Drug Gene Interaction Database)POM121
DoCM (Curated mutations)POM121 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POM121 (select a term)
intoGenPOM121
Cancer3DPOM121(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615753   
Orphanet
MedgenPOM121
Genetic Testing Registry POM121
NextProtQ96HA1 [Medical]
TSGene9883
GENETestsPOM121
Target ValidationPOM121
Huge Navigator POM121 [HugePedia]
snp3D : Map Gene to Disease9883
BioCentury BCIQPOM121
ClinGenPOM121
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9883
Chemical/Pharm GKB GenePA134987951
Clinical trialPOM121
Miscellaneous
canSAR (ICR)POM121 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOM121
EVEXPOM121
GoPubMedPOM121
iHOPPOM121
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 13:05:56 CET 2017

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