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POP1 (POP1 homolog, ribonuclease P/MRP subunit)

Identity

Alias_namesprocessing of precursor 1
Other aliasANXD2
HGNC (Hugo) POP1
LocusID (NCBI) 10940
Atlas_Id 52184
Location 8q22.2  [Link to chromosome band 8q22]
Location_base_pair Starts at 98117293 and ends at 98159841 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM167A-AS1 (8p23.1) / POP1 (8q22.2)POP1 (8q22.2) / MATN2 (8q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POP1   30129
Cards
Entrez_Gene (NCBI)POP1  10940  POP1 homolog, ribonuclease P/MRP subunit
AliasesANXD2
GeneCards (Weizmann)POP1
Ensembl hg19 (Hinxton)ENSG00000104356 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104356 [Gene_View]  chr8:98117293-98159841 [Contig_View]  POP1 [Vega]
ICGC DataPortalENSG00000104356
TCGA cBioPortalPOP1
AceView (NCBI)POP1
Genatlas (Paris)POP1
WikiGenes10940
SOURCE (Princeton)POP1
Genetics Home Reference (NIH)POP1
Genomic and cartography
GoldenPath hg38 (UCSC)POP1  -     chr8:98117293-98159841 +  8q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POP1  -     8q22.2   [Description]    (hg19-Feb_2009)
EnsemblPOP1 - 8q22.2 [CytoView hg19]  POP1 - 8q22.2 [CytoView hg38]
Mapping of homologs : NCBIPOP1 [Mapview hg19]  POP1 [Mapview hg38]
OMIM602486   617396   
Gene and transcription
Genbank (Entrez)AK000837 AK291434 BC011529 BF511088 BP249298
RefSeq transcript (Entrez)NM_001145860 NM_001145861 NM_015029
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POP1
Cluster EST : UnigeneHs.252828 [ NCBI ]
CGAP (NCI)Hs.252828
Alternative Splicing GalleryENSG00000104356
Gene ExpressionPOP1 [ NCBI-GEO ]   POP1 [ EBI - ARRAY_EXPRESS ]   POP1 [ SEEK ]   POP1 [ MEM ]
Gene Expression Viewer (FireBrowse)POP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10940
GTEX Portal (Tissue expression)POP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99575   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99575  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99575
Splice isoforms : SwissVarQ99575
PhosPhoSitePlusQ99575
Domains : Interpro (EBI)POPLD    RNase_P/MRP_POP1   
Domain families : Pfam (Sanger)POP1 (PF06978)    POPLD (PF08170)   
Domain families : Pfam (NCBI)pfam06978    pfam08170   
Conserved Domain (NCBI)POP1
DMDM Disease mutations10940
Blocks (Seattle)POP1
SuperfamilyQ99575
Human Protein AtlasENSG00000104356
Peptide AtlasQ99575
HPRD03923
IPIIPI00293331   IPI00975761   
Protein Interaction databases
DIP (DOE-UCLA)Q99575
IntAct (EBI)Q99575
FunCoupENSG00000104356
BioGRIDPOP1
STRING (EMBL)POP1
ZODIACPOP1
Ontologies - Pathways
QuickGOQ99575
Ontology : AmiGOribonuclease MRP activity  ribonuclease MRP complex  tRNA 5'-leader removal  RNA binding  ribonuclease P activity  protein binding  extracellular space  nucleoplasm  nucleolar ribonuclease P complex  nucleolus  mitochondrion  Golgi apparatus  tRNA processing  tRNA catabolic process  intracellular membrane-bounded organelle  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBIribonuclease MRP activity  ribonuclease MRP complex  tRNA 5'-leader removal  RNA binding  ribonuclease P activity  protein binding  extracellular space  nucleoplasm  nucleolar ribonuclease P complex  nucleolus  mitochondrion  Golgi apparatus  tRNA processing  tRNA catabolic process  intracellular membrane-bounded organelle  RNA phosphodiester bond hydrolysis, endonucleolytic  
Pathways : KEGGRibosome biogenesis in eukaryotes    RNA transport   
NDEx NetworkPOP1
Atlas of Cancer Signalling NetworkPOP1
Wikipedia pathwaysPOP1
Orthology - Evolution
OrthoDB10940
GeneTree (enSembl)ENSG00000104356
Phylogenetic Trees/Animal Genes : TreeFamPOP1
HOVERGENQ99575
HOGENOMQ99575
Homologs : HomoloGenePOP1
Homology/Alignments : Family Browser (UCSC)POP1
Gene fusions - Rearrangements
Fusion : MitelmanPOP1/MATN2 [8q22.2/8q22.1]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POP1
dbVarPOP1
ClinVarPOP1
1000_GenomesPOP1 
Exome Variant ServerPOP1
ExAC (Exome Aggregation Consortium)POP1 (select the gene name)
Genetic variants : HAPMAP10940
Genomic Variants (DGV)POP1 [DGVbeta]
DECIPHERPOP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOP1 
Mutations
ICGC Data PortalPOP1 
TCGA Data PortalPOP1 
Broad Tumor PortalPOP1
OASIS PortalPOP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POP1
DgiDB (Drug Gene Interaction Database)POP1
DoCM (Curated mutations)POP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POP1 (select a term)
intoGenPOP1
Cancer3DPOP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602486    617396   
Orphanet12281   
MedgenPOP1
Genetic Testing Registry POP1
NextProtQ99575 [Medical]
TSGene10940
GENETestsPOP1
Target ValidationPOP1
Huge Navigator POP1 [HugePedia]
snp3D : Map Gene to Disease10940
BioCentury BCIQPOP1
ClinGenPOP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10940
Chemical/Pharm GKB GenePA134907403
Clinical trialPOP1
Miscellaneous
canSAR (ICR)POP1 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOP1
EVEXPOP1
GoPubMedPOP1
iHOPPOP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:22 CEST 2017

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