POSTN (periostin)

2007-02-01  

Identity

HGNC
LOCATION
13q13.3
LOCUSID
ALIAS
OSF-2,OSF2,PDLPOSTN,PN
FUSION GENES

Other Information

Locus ID:

NCBI: 10631
MIM: 608777
HGNC: 16953
Ensembl: ENSG00000133110

Variants:

dbSNP: 10631
ClinVar: 10631
TCGA: ENSG00000133110
COSMIC: POSTN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133110ENST00000379742Q15063
ENSG00000133110ENST00000379742A0A024RDT5
ENSG00000133110ENST00000379743Q15063
ENSG00000133110ENST00000379747Q15063
ENSG00000133110ENST00000379747A0A024RDS2
ENSG00000133110ENST00000379749B1ALD9
ENSG00000133110ENST00000541179Q15063
ENSG00000133110ENST00000541481Q15063

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
122350072002Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility.193
255807342015Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth.188
150935402004Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway.182
182089762008Periostin is essential for cardiac healing after acute myocardial infarction.151
206607322010Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma.122
198930212009Origin of cardiac fibroblasts and the role of periostin.106
150827922004Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.105
170436572007Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway.102
190791902008Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses.90
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85

Citation

Dessen P

POSTN (periostin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46198/postn