| Nomenclature |
|---|
| HGNC (Hugo) | POU2F1 9212 |
| Cards |
|---|
| Entrez_Gene (NCBI) | POU2F1 5451 POU class 2 homeobox 1 |
| Aliases | OCT1; OTF1; oct-1B |
| GeneCards (Weizmann) | POU2F1 |
| Ensembl hg19 (Hinxton) | ENSG00000143190 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000143190 [Gene_View] chr1:167329044-167427345 [Contig_View] POU2F1 [Vega] |
| ICGC DataPortal | ENSG00000143190 |
| TCGA cBioPortal | POU2F1 |
| AceView (NCBI) | POU2F1 |
| Genatlas (Paris) | POU2F1 |
| WikiGenes | 5451 |
| SOURCE (Princeton) | POU2F1 |
| Genetics Home Reference (NIH) | POU2F1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | POU2F1 - chr1:167329044-167427345 + 1q24.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | POU2F1 - 1q24.2 [Description] (hg19-Feb_2009) |
| Ensembl | POU2F1 - 1q24.2 [CytoView hg19] POU2F1 - 1q24.2 [CytoView hg38] |
| Mapping of homologs : NCBI | POU2F1 [Mapview hg19] POU2F1 [Mapview hg38] |
| OMIM | 164175 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AH004418 AK091438 AK124826 AK302525 AK303201 |
| RefSeq transcript (Entrez) | NM_001198783 NM_001198786 NM_002697 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | POU2F1 |
| Cluster EST : Unigene | Hs.283402 [ NCBI ] |
| CGAP (NCI) | Hs.283402 |
| Alternative Splicing Gallery | ENSG00000143190 |
| Gene Expression | POU2F1 [ NCBI-GEO ] POU2F1 [ EBI - ARRAY_EXPRESS ]
POU2F1 [ SEEK ] POU2F1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | POU2F1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5451 |
| GTEX Portal (Tissue expression) | POU2F1 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P14859 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P14859 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P14859 |
| Splice isoforms : SwissVar | P14859 |
| PhosPhoSitePlus | P14859 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) POU_1 (PS00035) POU_2 (PS00465) POU_3 (PS51179) |
| Domains : Interpro (EBI) | Homeobox-like Homeobox_CS Homeobox_dom Lambda_DNA-bd_dom POU POU_dom TF_octamer |
| Domain families : Pfam (Sanger) | Homeobox (PF00046) Pou (PF00157) |
| Domain families : Pfam (NCBI) | pfam00046 pfam00157 |
| Domain families : Smart (EMBL) | HOX (SM00389) POU (SM00352) |
| Conserved Domain (NCBI) | POU2F1 |
| DMDM Disease mutations | 5451 |
| Blocks (Seattle) | POU2F1 |
| PDB (SRS) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| PDB (PDBSum) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| PDB (IMB) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| PDB (RSDB) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| Structural Biology KnowledgeBase | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| SCOP (Structural Classification of Proteins) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| CATH (Classification of proteins structures) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| Superfamily | P14859 |
| Human Protein Atlas | ENSG00000143190 |
| Peptide Atlas | P14859 |
| HPRD | 01250 |
| IPI | IPI00219171 IPI00555806 IPI00555623 IPI00470450 IPI00640177 IPI00027828 IPI01011031 IPI01013664 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P14859 |
| IntAct (EBI) | P14859 |
| FunCoup | ENSG00000143190 |
| BioGRID | POU2F1 |
| STRING (EMBL) | POU2F1 |
| ZODIAC | POU2F1 |
| Ontologies - Pathways |
|---|
| QuickGO | P14859 |
| Ontology : AmiGO | RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding protein binding nucleus nucleoplasm nucleoplasm endoplasmic reticulum regulation of transcription from RNA polymerase II promoter snRNA transcription from RNA polymerase II promoter intracellular membrane-bounded organelle sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor complex |
| Ontology : EGO-EBI | RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding protein binding nucleus nucleoplasm nucleoplasm endoplasmic reticulum regulation of transcription from RNA polymerase II promoter snRNA transcription from RNA polymerase II promoter intracellular membrane-bounded organelle sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor complex |
| NDEx Network | POU2F1 |
| Atlas of Cancer Signalling Network | POU2F1 |
| Wikipedia pathways | POU2F1 |
| Orthology - Evolution |
|---|
| OrthoDB | 5451 |
| GeneTree (enSembl) | ENSG00000143190 |
| Phylogenetic Trees/Animal Genes : TreeFam | POU2F1 |
| HOVERGEN | P14859 |
| HOGENOM | P14859 |
| Homologs : HomoloGene | POU2F1 |
| Homology/Alignments : Family Browser (UCSC) | POU2F1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | POU2F1/CD247 [1q24.2/1q24.2] |
| Fusion: TCGA | POU2F1 1q24.2 CD247 1q24.2 BRCA |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | POU2F1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | POU2F1 |
| dbVar | POU2F1 |
| ClinVar | POU2F1 |
| 1000_Genomes | POU2F1 |
| Exome Variant Server | POU2F1 |
| ExAC (Exome Aggregation Consortium) | POU2F1 (select the gene name) |
| Genetic variants : HAPMAP | 5451 |
| Genomic Variants (DGV) | POU2F1 [DGVbeta] |
| DECIPHER | POU2F1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | POU2F1 |
| Mutations |
|---|
| ICGC Data Portal | POU2F1 |
| TCGA Data Portal | POU2F1 |
| Broad Tumor Portal | POU2F1 |
| OASIS Portal | POU2F1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | POU2F1 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | POU2F1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search POU2F1 |
| DgiDB (Drug Gene Interaction Database) | POU2F1 |
| DoCM (Curated mutations) | POU2F1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | POU2F1 (select a term) |
| intoGen | POU2F1 |
| Cancer3D | POU2F1(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 164175 |
| Orphanet | |
| Medgen | POU2F1 |
| Genetic Testing Registry | POU2F1
|
| NextProt | P14859 [Medical] |
| TSGene | 5451 |
| GENETests | POU2F1 |
| Target Validation | POU2F1 |
| Huge Navigator |
POU2F1 [HugePedia] |
| snp3D : Map Gene to Disease | 5451 |
| BioCentury BCIQ | POU2F1 |
| ClinGen | POU2F1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 5451 |
| Chemical/Pharm GKB Gene | PA33536 |
| Clinical trial | POU2F1 |
| Miscellaneous |
|---|
| canSAR (ICR) | POU2F1 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 176 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | POU2F1 |
| EVEX | POU2F1 |
| GoPubMed | POU2F1 |
| iHOP | POU2F1 |
