| Nomenclature |
|---|
| HGNC (Hugo) | POU2F1 9212 |
| Cards |
|---|
| Entrez_Gene (NCBI) | POU2F1 5451 POU class 2 homeobox 1 |
| Aliases | OCT1; OTF1; oct-1B |
| GeneCards (Weizmann) | POU2F1 |
| Ensembl hg19 (Hinxton) | ENSG00000143190 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000143190 [Gene_View] ENSG00000143190 [Sequence] chr1:167220829-167427345 [Contig_View] POU2F1 [Vega] |
| ICGC DataPortal | ENSG00000143190 |
| TCGA cBioPortal | POU2F1 |
| AceView (NCBI) | POU2F1 |
| Genatlas (Paris) | POU2F1 |
| WikiGenes | 5451 |
| SOURCE (Princeton) | POU2F1 |
| Genetics Home Reference (NIH) | POU2F1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | POU2F1 - chr1:167220829-167427345 + 1q24.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | POU2F1 - 1q24.2 [Description] (hg19-Feb_2009) |
| Ensembl | POU2F1 - 1q24.2 [CytoView hg19] POU2F1 - 1q24.2 [CytoView hg38] |
| Mapping of homologs : NCBI | POU2F1 [Mapview hg19] POU2F1 [Mapview hg38] |
| OMIM | 164175 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK091438 AK124826 AK302525 AK303201 AK308004 |
| RefSeq transcript (Entrez) | NM_001198783 NM_001198786 NM_001365848 NM_001365849 NM_002697 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | POU2F1 |
| Cluster EST : Unigene | Hs.283402 [ NCBI ] |
| CGAP (NCI) | Hs.283402 |
| Alternative Splicing Gallery | ENSG00000143190 |
| Gene Expression | POU2F1 [ NCBI-GEO ] POU2F1 [ EBI - ARRAY_EXPRESS ]
POU2F1 [ SEEK ] POU2F1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | POU2F1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5451 |
| GTEX Portal (Tissue expression) | POU2F1 |
| Human Protein Atlas | ENSG00000143190-POU2F1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P14859 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P14859 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P14859 |
| Splice isoforms : SwissVar | P14859 |
| PhosPhoSitePlus | P14859 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) POU_1 (PS00035) POU_2 (PS00465) POU_3 (PS51179) |
| Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom Lambda_DNA-bd_dom_sf POU POU_dom TF_octamer |
| Domain families : Pfam (Sanger) | Homeobox (PF00046) Pou (PF00157) |
| Domain families : Pfam (NCBI) | pfam00046 pfam00157 |
| Domain families : Smart (EMBL) | HOX (SM00389) POU (SM00352) |
| Conserved Domain (NCBI) | POU2F1 |
| DMDM Disease mutations | 5451 |
| Blocks (Seattle) | POU2F1 |
| PDB (SRS) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| PDB (PDBSum) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| PDB (IMB) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| PDB (RSDB) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| Structural Biology KnowledgeBase | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| SCOP (Structural Classification of Proteins) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| CATH (Classification of proteins structures) | 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU |
| Superfamily | P14859 |
| Human Protein Atlas [tissue] | ENSG00000143190-POU2F1 [tissue] |
| Peptide Atlas | P14859 |
| HPRD | 01250 |
| IPI | IPI00219171 IPI00555806 IPI00555623 IPI00470450 IPI00640177 IPI00027828 IPI01011031 IPI01013664 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P14859 |
| IntAct (EBI) | P14859 |
| FunCoup | ENSG00000143190 |
| BioGRID | POU2F1 |
| STRING (EMBL) | POU2F1 |
| ZODIAC | POU2F1 |
| Ontologies - Pathways |
|---|
| QuickGO | P14859 |
| Ontology : AmiGO | RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding DNA binding protein binding nucleus nucleoplasm nucleoplasm endoplasmic reticulum cytokine-mediated signaling pathway snRNA transcription by RNA polymerase II intracellular membrane-bounded organelle sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II RNA polymerase II transcription factor complex |
| Ontology : EGO-EBI | RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding DNA binding protein binding nucleus nucleoplasm nucleoplasm endoplasmic reticulum cytokine-mediated signaling pathway snRNA transcription by RNA polymerase II intracellular membrane-bounded organelle sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II RNA polymerase II transcription factor complex |
| NDEx Network | POU2F1 |
| Atlas of Cancer Signalling Network | POU2F1 |
| Wikipedia pathways | POU2F1 |
| Orthology - Evolution |
|---|
| OrthoDB | 5451 |
| GeneTree (enSembl) | ENSG00000143190 |
| Phylogenetic Trees/Animal Genes : TreeFam | POU2F1 |
| HOVERGEN | P14859 |
| HOGENOM | P14859 |
| Homologs : HomoloGene | POU2F1 |
| Homology/Alignments : Family Browser (UCSC) | POU2F1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | POU2F1/CD247 [1q24.2/1q24.2] |
| Fusion Portal | POU2F1 1q24.2 CD247 1q24.2 BRCA |
| Fusion : Quiver | POU2F1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | POU2F1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | POU2F1 |
| dbVar | POU2F1 |
| ClinVar | POU2F1 |
| 1000_Genomes | POU2F1 |
| Exome Variant Server | POU2F1 |
| ExAC (Exome Aggregation Consortium) | ENSG00000143190 |
| GNOMAD Browser | ENSG00000143190 |
| Varsome Browser | POU2F1 |
| Genetic variants : HAPMAP | 5451 |
| Genomic Variants (DGV) | POU2F1 [DGVbeta] |
| DECIPHER | POU2F1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | POU2F1 |
| Mutations |
|---|
| ICGC Data Portal | POU2F1 |
| TCGA Data Portal | POU2F1 |
| Broad Tumor Portal | POU2F1 |
| OASIS Portal | POU2F1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | POU2F1 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | POU2F1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search POU2F1 |
| DgiDB (Drug Gene Interaction Database) | POU2F1 |
| DoCM (Curated mutations) | POU2F1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | POU2F1 (select a term) |
| intoGen | POU2F1 |
| Cancer3D | POU2F1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 164175 |
| Orphanet | |
| DisGeNET | POU2F1 |
| Medgen | POU2F1 |
| Genetic Testing Registry | POU2F1
|
| NextProt | P14859 [Medical] |
| TSGene | 5451 |
| GENETests | POU2F1 |
| Target Validation | POU2F1 |
| Huge Navigator |
POU2F1 [HugePedia] |
| snp3D : Map Gene to Disease | 5451 |
| BioCentury BCIQ | POU2F1 |
| ClinGen | POU2F1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 5451 |
| Chemical/Pharm GKB Gene | PA33536 |
| Clinical trial | POU2F1 |
| Miscellaneous |
|---|
| canSAR (ICR) | POU2F1 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 195 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | POU2F1 |
| EVEX | POU2F1 |
| GoPubMed | POU2F1 |
| iHOP | POU2F1 |
