Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

POU2F3 (POU class 2 homeobox 3)

Identity

Alias_namesPOU domain class 2
Alias_symbol (synonym)OCT11
PLA-1
Skn-1a
Epoc-1
Other aliasOCT-11
OTF-11
PLA1
HGNC (Hugo) POU2F3
LocusID (NCBI) 25833
Atlas_Id 43760
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 120236640 and ends at 120319944 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARHGEF12 (11q23.3) / POU2F3 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POU2F3   19864
Cards
Entrez_Gene (NCBI)POU2F3  25833  POU class 2 homeobox 3
AliasesEpoc-1; OCT-11; OCT11; OTF-11; 
PLA-1; PLA1; Skn-1a
GeneCards (Weizmann)POU2F3
Ensembl hg19 (Hinxton)ENSG00000137709 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137709 [Gene_View]  chr11:120236640-120319944 [Contig_View]  POU2F3 [Vega]
ICGC DataPortalENSG00000137709
TCGA cBioPortalPOU2F3
AceView (NCBI)POU2F3
Genatlas (Paris)POU2F3
WikiGenes25833
SOURCE (Princeton)POU2F3
Genetics Home Reference (NIH)POU2F3
Genomic and cartography
GoldenPath hg38 (UCSC)POU2F3  -     chr11:120236640-120319944 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POU2F3  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblPOU2F3 - 11q23.3 [CytoView hg19]  POU2F3 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIPOU2F3 [Mapview hg19]  POU2F3 [Mapview hg38]
OMIM607394   
Gene and transcription
Genbank (Entrez)AF133895 AF162278 AF162715 AJ012214 AK097382
RefSeq transcript (Entrez)NM_001244682 NM_014352
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POU2F3
Cluster EST : UnigeneHs.227115 [ NCBI ]
CGAP (NCI)Hs.227115
Alternative Splicing GalleryENSG00000137709
Gene ExpressionPOU2F3 [ NCBI-GEO ]   POU2F3 [ EBI - ARRAY_EXPRESS ]   POU2F3 [ SEEK ]   POU2F3 [ MEM ]
Gene Expression Viewer (FireBrowse)POU2F3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25833
GTEX Portal (Tissue expression)POU2F3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKI9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKI9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKI9
Splice isoforms : SwissVarQ9UKI9
PhosPhoSitePlusQ9UKI9
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    POU_1 (PS00035)    POU_2 (PS00465)    POU_3 (PS51179)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Lambda_DNA-bd_dom    POU    POU_dom    TF_octamer   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Pou (PF00157)   
Domain families : Pfam (NCBI)pfam00046    pfam00157   
Domain families : Smart (EMBL)HOX (SM00389)  POU (SM00352)  
Conserved Domain (NCBI)POU2F3
DMDM Disease mutations25833
Blocks (Seattle)POU2F3
SuperfamilyQ9UKI9
Human Protein AtlasENSG00000137709
Peptide AtlasQ9UKI9
HPRD09582
IPIIPI00748827   IPI01009181   IPI00984752   IPI00981679   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKI9
IntAct (EBI)Q9UKI9
FunCoupENSG00000137709
BioGRIDPOU2F3
STRING (EMBL)POU2F3
ZODIACPOU2F3
Ontologies - Pathways
QuickGOQ9UKI9
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  protein binding  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  epidermis development  sequence-specific DNA binding  negative regulation by host of viral transcription  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  protein binding  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  epidermis development  sequence-specific DNA binding  negative regulation by host of viral transcription  positive regulation of transcription from RNA polymerase II promoter  
Pathways : KEGGHerpes simplex infection   
NDEx NetworkPOU2F3
Atlas of Cancer Signalling NetworkPOU2F3
Wikipedia pathwaysPOU2F3
Orthology - Evolution
OrthoDB25833
GeneTree (enSembl)ENSG00000137709
Phylogenetic Trees/Animal Genes : TreeFamPOU2F3
HOVERGENQ9UKI9
HOGENOMQ9UKI9
Homologs : HomoloGenePOU2F3
Homology/Alignments : Family Browser (UCSC)POU2F3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOU2F3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POU2F3
dbVarPOU2F3
ClinVarPOU2F3
1000_GenomesPOU2F3 
Exome Variant ServerPOU2F3
ExAC (Exome Aggregation Consortium)POU2F3 (select the gene name)
Genetic variants : HAPMAP25833
Genomic Variants (DGV)POU2F3 [DGVbeta]
DECIPHERPOU2F3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOU2F3 
Mutations
ICGC Data PortalPOU2F3 
TCGA Data PortalPOU2F3 
Broad Tumor PortalPOU2F3
OASIS PortalPOU2F3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOU2F3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOU2F3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POU2F3
DgiDB (Drug Gene Interaction Database)POU2F3
DoCM (Curated mutations)POU2F3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POU2F3 (select a term)
intoGenPOU2F3
Cancer3DPOU2F3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607394   
Orphanet
MedgenPOU2F3
Genetic Testing Registry POU2F3
NextProtQ9UKI9 [Medical]
TSGene25833
GENETestsPOU2F3
Target ValidationPOU2F3
Huge Navigator POU2F3 [HugePedia]
snp3D : Map Gene to Disease25833
BioCentury BCIQPOU2F3
ClinGenPOU2F3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25833
Chemical/Pharm GKB GenePA134963258
Clinical trialPOU2F3
Miscellaneous
canSAR (ICR)POU2F3 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOU2F3
EVEXPOU2F3
GoPubMedPOU2F3
iHOPPOU2F3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:03:57 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.