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POU3F4 (POU class 3 homeobox 4)

Identity

Alias_namesDFN3
POU domain class 3, transcription factor 4
Alias_symbol (synonym)BRN4
OTF9
DFNX2
Other aliasBRAIN-4
BRN-4
OCT-9
OTF-9
HGNC (Hugo) POU3F4
LocusID (NCBI) 5456
Atlas_Id 72094
Location Xq21.1  [Link to chromosome band Xq21]
Location_base_pair Starts at 82763269 and ends at 82764775 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POU3F4   9217
Cards
Entrez_Gene (NCBI)POU3F4  5456  POU class 3 homeobox 4
AliasesBRAIN-4; BRN-4; BRN4; DFN3; 
DFNX2; OCT-9; OTF-9; OTF9
GeneCards (Weizmann)POU3F4
Ensembl hg19 (Hinxton) [Gene_View]  chrX:82763269-82764775 [Contig_View]  POU3F4 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chrX:82763269-82764775 [Contig_View]  POU3F4 [Vega]
TCGA cBioPortalPOU3F4
AceView (NCBI)POU3F4
Genatlas (Paris)POU3F4
WikiGenes5456
SOURCE (Princeton)POU3F4
Genetics Home Reference (NIH)POU3F4
Genomic and cartography
GoldenPath hg19 (UCSC)POU3F4  -     chrX:82763269-82764775 +  Xq21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)POU3F4  -     Xq21.1   [Description]    (hg38-Dec_2013)
EnsemblPOU3F4 - Xq21.1 [CytoView hg19]  POU3F4 - Xq21.1 [CytoView hg38]
Mapping of homologs : NCBIPOU3F4 [Mapview hg19]  POU3F4 [Mapview hg38]
OMIM300039   304400   
Gene and transcription
Genbank (Entrez)AK314967 BC141561 BC146551 X82324
RefSeq transcript (Entrez)NM_000307
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_009936 NT_011651 NW_004929444
Consensus coding sequences : CCDS (NCBI)POU3F4
Cluster EST : UnigeneHs.2229 [ NCBI ]
CGAP (NCI)Hs.2229
Gene ExpressionPOU3F4 [ NCBI-GEO ]   POU3F4 [ EBI - ARRAY_EXPRESS ]   POU3F4 [ SEEK ]   POU3F4 [ MEM ]
Gene Expression Viewer (FireBrowse)POU3F4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5456
GTEX Portal (Tissue expression)POU3F4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49335   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49335  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49335
Splice isoforms : SwissVarP49335
PhosPhoSitePlusP49335
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    POU_1 (PS00035)    POU_2 (PS00465)    POU_3 (PS51179)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeodomain-like    Lambda_DNA-bd_dom    POU    POU_specific    TF_POU_3   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Pou (PF00157)   
Domain families : Pfam (NCBI)pfam00046    pfam00157   
Domain families : Smart (EMBL)HOX (SM00389)  POU (SM00352)  
Conserved Domain (NCBI)POU3F4
DMDM Disease mutations5456
Blocks (Seattle)POU3F4
SuperfamilyP49335
Peptide AtlasP49335
HPRD02076
IPIIPI00026790   
Protein Interaction databases
DIP (DOE-UCLA)P49335
IntAct (EBI)P49335
BioGRIDPOU3F4
STRING (EMBL)POU3F4
ZODIACPOU3F4
Ontologies - Pathways
QuickGOP49335
Ontology : AmiGOAT DNA binding  double-stranded DNA binding  sequence-specific DNA binding transcription factor activity  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  sensory perception of sound  forebrain neuron differentiation  cochlea morphogenesis  negative regulation of mesenchymal cell apoptotic process  
Ontology : EGO-EBIAT DNA binding  double-stranded DNA binding  sequence-specific DNA binding transcription factor activity  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  sensory perception of sound  forebrain neuron differentiation  cochlea morphogenesis  negative regulation of mesenchymal cell apoptotic process  
NDEx NetworkPOU3F4
Atlas of Cancer Signalling NetworkPOU3F4
Wikipedia pathwaysPOU3F4
Orthology - Evolution
OrthoDB5456
Phylogenetic Trees/Animal Genes : TreeFamPOU3F4
HOVERGENP49335
HOGENOMP49335
Homologs : HomoloGenePOU3F4
Homology/Alignments : Family Browser (UCSC)POU3F4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOU3F4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POU3F4
dbVarPOU3F4
ClinVarPOU3F4
1000_GenomesPOU3F4 
Exome Variant ServerPOU3F4
ExAC (Exome Aggregation Consortium)POU3F4 (select the gene name)
Genetic variants : HAPMAP5456
Genomic Variants (DGV)POU3F4 [DGVbeta]
DECIPHER (Syndromes)X:82763269-82764775  
CONAN: Copy Number AnalysisPOU3F4 
Mutations
ICGC Data PortalPOU3F4 
TCGA Data PortalPOU3F4 
Broad Tumor PortalPOU3F4
OASIS PortalPOU3F4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOU3F4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOU3F4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch POU3F4
DgiDB (Drug Gene Interaction Database)POU3F4
DoCM (Curated mutations)POU3F4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POU3F4 (select a term)
intoGenPOU3F4
Cancer3DPOU3F4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300039    304400   
Orphanet17562    157   
MedgenPOU3F4
Genetic Testing Registry POU3F4
NextProtP49335 [Medical]
TSGene5456
GENETestsPOU3F4
Huge Navigator POU3F4 [HugePedia]
snp3D : Map Gene to Disease5456
BioCentury BCIQPOU3F4
ClinGenPOU3F4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5456
Chemical/Pharm GKB GenePA33541
Clinical trialPOU3F4
Miscellaneous
canSAR (ICR)POU3F4 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOU3F4
EVEXPOU3F4
GoPubMedPOU3F4
iHOPPOU3F4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:16 CET 2017

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