Atlas of Genetics and Cytogenetics in Oncology and Haematology


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POU4F2 (POU class 4 homeobox 2)

Identity

Other namesBRN3.2
BRN3B
Brn-3b
HGNC (Hugo) POU4F2
LocusID (NCBI) 5458
Location 4q31.22
Location_base_pair Starts at 147560045 and ends at 147563623 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)POU4F2   9219
Cards
Entrez_Gene (NCBI)POU4F2  5458  POU class 4 homeobox 2
GeneCards (Weizmann)POU4F2
Ensembl (Hinxton)ENSG00000151615 [Gene_View]  chr4:147560045-147563623 [Contig_View]  POU4F2 [Vega]
ICGC DataPortalENSG00000151615
cBioPortalPOU4F2
AceView (NCBI)POU4F2
Genatlas (Paris)POU4F2
WikiGenes5458
SOURCE (Princeton)NM_004575
Genomic and cartography
GoldenPath (UCSC)POU4F2  -  4q31.22   chr4:147560045-147563623 +  4q31.22   [Description]    (hg19-Feb_2009)
EnsemblPOU4F2 - 4q31.22 [CytoView]
Mapping of homologs : NCBIPOU4F2 [Mapview]
OMIM113725   
Gene and transcription
Genbank (Entrez)AK314982 BC136344 BC136345 BY796838 DB082745
RefSeq transcript (Entrez)NM_004575
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838921 NW_004929320
Consensus coding sequences : CCDS (NCBI)POU4F2
Cluster EST : UnigeneHs.266 [ NCBI ]
CGAP (NCI)Hs.266
Alternative Splicing : Fast-db (Paris)GSHG0022897
Alternative Splicing GalleryENSG00000151615
Gene ExpressionPOU4F2 [ NCBI-GEO ]     POU4F2 [ SEEK ]   POU4F2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12837 (Uniprot)
NextProtQ12837  [Medical]
With graphics : InterProQ12837
Splice isoforms : SwissVarQ12837 (Swissvar)
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    POU_1 (PS00035)    POU_2 (PS00465)    POU_3 (PS51179)   
Domains : Interpro (EBI)Homeobox_CS [organisation]   Homeobox_dom [organisation]   Homeodomain-like [organisation]   Lambda_DNA-bd_dom [organisation]   POU [organisation]   POU_specific [organisation]  
Related proteins : CluSTrQ12837
Domain families : Pfam (Sanger)Homeobox (PF00046)    Pou (PF00157)   
Domain families : Pfam (NCBI)pfam00046    pfam00157   
Domain families : Smart (EMBL)HOX (SM00389)  POU (SM00352)  
DMDM Disease mutations5458
Blocks (Seattle)Q12837
Human Protein AtlasENSG00000151615 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ12837
HPRD00220
IPIIPI00029713   
Protein Interaction databases
DIP (DOE-UCLA)Q12837
IntAct (EBI)Q12837
FunCoupENSG00000151615
BioGRIDPOU4F2
InParanoidQ12837
Interologous Interaction database Q12837
IntegromeDBPOU4F2
STRING (EMBL)POU4F2
Ontologies - Pathways
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  MAPK cascade  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  chromatin binding  nucleus  nucleus  transcription, DNA-templated  axon guidance  sensory perception of sound  nuclear speck  neuron differentiation  intracellular estrogen receptor signaling pathway  retinal ganglion cell axon guidance  positive regulation of cell differentiation  positive regulation of transcription from RNA polymerase II promoter  axon extension  neuromuscular process controlling balance  retina development in camera-type eye  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  MAPK cascade  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  chromatin binding  nucleus  nucleus  transcription, DNA-templated  axon guidance  sensory perception of sound  nuclear speck  neuron differentiation  intracellular estrogen receptor signaling pathway  retinal ganglion cell axon guidance  positive regulation of cell differentiation  positive regulation of transcription from RNA polymerase II promoter  axon extension  neuromuscular process controlling balance  retina development in camera-type eye  
Protein Interaction DatabasePOU4F2
Wikipedia pathwaysPOU4F2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)POU4F2
snp3D : Map Gene to Disease5458
SNP (GeneSNP Utah)POU4F2
SNP : HGBasePOU4F2
Genetic variants : HAPMAPPOU4F2
Exome VariantPOU4F2
1000_GenomesPOU4F2 
ICGC programENSG00000151615 
Somatic Mutations in Cancer : COSMICPOU4F2 
CONAN: Copy Number AnalysisPOU4F2 
Mutations and Diseases : HGMDPOU4F2
Mutations and Diseases : intOGenPOU4F2
Genomic VariantsPOU4F2  POU4F2 [DGVbeta]
dbVarPOU4F2
ClinVarPOU4F2
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM113725   
MedgenPOU4F2
GENETestsPOU4F2
Disease Genetic AssociationPOU4F2
Huge Navigator POU4F2 [HugePedia]  POU4F2 [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePOU4F2
Homology/Alignments : Family Browser (UCSC)POU4F2
Phylogenetic Trees/Animal Genes : TreeFamPOU4F2
Chemical/Protein Interactions : CTD5458
Chemical/Pharm GKB GenePA33543
Clinical trialPOU4F2
Cancer Resource (Charite)ENSG00000151615
Other databases
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
CoreMinePOU4F2
iHOPPOU4F2
OncoSearchPOU4F2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:00:39 CEST 2014

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