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POU5F1B (POU class 5 homeobox 1B)

Identity

Alias_namesOTF3P1
POU5F1P1
POU domain class 5, transcription factor 1 pseudogene 1
POU class 5 homeobox 1 pseudogene 1
Alias_symbol (synonym)OTF3C
Other aliasOCT4-PG1
OCT4PG1
POU5F1P4
POU5FLC20
POU5FLC8
HGNC (Hugo) POU5F1B
LocusID (NCBI) 5462
Atlas_Id 51472
Location 8q24.21  [Link to chromosome band 8q24]
Location_base_pair Starts at 128427857 and ends at 128429441 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POU5F1B   9223
Cards
Entrez_Gene (NCBI)POU5F1B  5462  POU class 5 homeobox 1B
AliasesOCT4-PG1; OCT4PG1; OTF3C; OTF3P1; 
POU5F1P1; POU5F1P4; POU5FLC20; POU5FLC8
GeneCards (Weizmann)POU5F1B
Ensembl hg19 (Hinxton)ENSG00000212993 [Gene_View]  chr8:128427857-128429441 [Contig_View]  POU5F1B [Vega]
Ensembl hg38 (Hinxton)ENSG00000212993 [Gene_View]  chr8:128427857-128429441 [Contig_View]  POU5F1B [Vega]
ICGC DataPortalENSG00000212993
TCGA cBioPortalPOU5F1B
AceView (NCBI)POU5F1B
Genatlas (Paris)POU5F1B
WikiGenes5462
SOURCE (Princeton)POU5F1B
Genetics Home Reference (NIH)POU5F1B
Genomic and cartography
GoldenPath hg19 (UCSC)POU5F1B  -     chr8:128427857-128429441 +  8q24.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)POU5F1B  -     8q24.21   [Description]    (hg38-Dec_2013)
EnsemblPOU5F1B - 8q24.21 [CytoView hg19]  POU5F1B - 8q24.21 [CytoView hg38]
Mapping of homologs : NCBIPOU5F1B [Mapview hg19]  POU5F1B [Mapview hg38]
OMIM615739   
Gene and transcription
Genbank (Entrez)AF268615 AF268618 DQ486513 FM177969 FM177970
RefSeq transcript (Entrez)NM_001159542
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)POU5F1B
Cluster EST : UnigeneHs.450254 [ NCBI ]
CGAP (NCI)Hs.450254
Alternative Splicing GalleryENSG00000212993
Gene ExpressionPOU5F1B [ NCBI-GEO ]   POU5F1B [ EBI - ARRAY_EXPRESS ]   POU5F1B [ SEEK ]   POU5F1B [ MEM ]
Gene Expression Viewer (FireBrowse)POU5F1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5462
GTEX Portal (Tissue expression)POU5F1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06416   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ06416  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ06416
Splice isoforms : SwissVarQ06416
PhosPhoSitePlusQ06416
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    POU_1 (PS00035)    POU_2 (PS00465)    POU_3 (PS51179)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeodomain-like    Lambda_DNA-bd_dom    POU    POU_dom    POU_dom_5   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Pou (PF00157)   
Domain families : Pfam (NCBI)pfam00046    pfam00157   
Domain families : Smart (EMBL)HOX (SM00389)  POU (SM00352)  
Conserved Domain (NCBI)POU5F1B
DMDM Disease mutations5462
Blocks (Seattle)POU5F1B
SuperfamilyQ06416
Human Protein AtlasENSG00000212993
Peptide AtlasQ06416
IPIIPI00183154   IPI01024889   IPI00963824   
Protein Interaction databases
DIP (DOE-UCLA)Q06416
IntAct (EBI)Q06416
FunCoupENSG00000212993
BioGRIDPOU5F1B
STRING (EMBL)POU5F1B
ZODIACPOU5F1B
Ontologies - Pathways
QuickGOQ06416
Ontology : AmiGOtranscription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  sequence-specific DNA binding  
Ontology : EGO-EBItranscription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  sequence-specific DNA binding  
NDEx NetworkPOU5F1B
Atlas of Cancer Signalling NetworkPOU5F1B
Wikipedia pathwaysPOU5F1B
Orthology - Evolution
OrthoDB5462
GeneTree (enSembl)ENSG00000212993
Phylogenetic Trees/Animal Genes : TreeFamPOU5F1B
HOVERGENQ06416
HOGENOMQ06416
Homologs : HomoloGenePOU5F1B
Homology/Alignments : Family Browser (UCSC)POU5F1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOU5F1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POU5F1B
dbVarPOU5F1B
ClinVarPOU5F1B
1000_GenomesPOU5F1B 
Exome Variant ServerPOU5F1B
ExAC (Exome Aggregation Consortium)POU5F1B (select the gene name)
Genetic variants : HAPMAP5462
Genomic Variants (DGV)POU5F1B [DGVbeta]
DECIPHER (Syndromes)8:128427857-128429441  ENSG00000212993
CONAN: Copy Number AnalysisPOU5F1B 
Mutations
ICGC Data PortalPOU5F1B 
TCGA Data PortalPOU5F1B 
Broad Tumor PortalPOU5F1B
OASIS PortalPOU5F1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOU5F1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOU5F1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POU5F1B
DgiDB (Drug Gene Interaction Database)POU5F1B
DoCM (Curated mutations)POU5F1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POU5F1B (select a term)
intoGenPOU5F1B
Cancer3DPOU5F1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615739   
Orphanet
MedgenPOU5F1B
Genetic Testing Registry POU5F1B
NextProtQ06416 [Medical]
TSGene5462
GENETestsPOU5F1B
Huge Navigator POU5F1B [HugePedia]
snp3D : Map Gene to Disease5462
BioCentury BCIQPOU5F1B
ClinGenPOU5F1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5462
Chemical/Pharm GKB GenePA33547
Clinical trialPOU5F1B
Miscellaneous
canSAR (ICR)POU5F1B (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOU5F1B
EVEXPOU5F1B
GoPubMedPOU5F1B
iHOPPOU5F1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:15:08 CEST 2017

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