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POU5F2 (POU domain class 5, transcription factor 2)

Identity

Alias_symbol (synonym)SPRM-1
FLJ25680
Other alias
HGNC (Hugo) POU5F2
LocusID (NCBI) 134187
Atlas_Id 72096
Location 5q15  [Link to chromosome band 5q15]
Location_base_pair Starts at 93740309 and ends at 93741603 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POU5F2   26367
Cards
Entrez_Gene (NCBI)POU5F2  134187  POU domain class 5, transcription factor 2
AliasesSPRM-1
GeneCards (Weizmann)POU5F2
Ensembl hg19 (Hinxton)ENSG00000248483 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000248483 [Gene_View]  chr5:93740309-93741603 [Contig_View]  POU5F2 [Vega]
ICGC DataPortalENSG00000248483
TCGA cBioPortalPOU5F2
AceView (NCBI)POU5F2
Genatlas (Paris)POU5F2
WikiGenes134187
SOURCE (Princeton)POU5F2
Genetics Home Reference (NIH)POU5F2
Genomic and cartography
GoldenPath hg38 (UCSC)POU5F2  -     chr5:93740309-93741603 -  5q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POU5F2  -     5q15   [Description]    (hg19-Feb_2009)
EnsemblPOU5F2 - 5q15 [CytoView hg19]  POU5F2 - 5q15 [CytoView hg38]
Mapping of homologs : NCBIPOU5F2 [Mapview hg19]  POU5F2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK098546 BC029532 BX641019 EU446850 Z21965
RefSeq transcript (Entrez)NM_153216
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POU5F2
Cluster EST : UnigeneHs.678995 [ NCBI ]
CGAP (NCI)Hs.678995
Alternative Splicing GalleryENSG00000248483
Gene ExpressionPOU5F2 [ NCBI-GEO ]   POU5F2 [ EBI - ARRAY_EXPRESS ]   POU5F2 [ SEEK ]   POU5F2 [ MEM ]
Gene Expression Viewer (FireBrowse)POU5F2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)134187
GTEX Portal (Tissue expression)POU5F2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N7G0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N7G0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N7G0
Splice isoforms : SwissVarQ8N7G0
PhosPhoSitePlusQ8N7G0
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)    POU_1 (PS00035)    POU_2 (PS00465)    POU_3 (PS51179)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_dom    Lambda_DNA-bd_dom    POU    POU_dom    POU_dom_5   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Pou (PF00157)   
Domain families : Pfam (NCBI)pfam00046    pfam00157   
Domain families : Smart (EMBL)HOX (SM00389)  POU (SM00352)  
Conserved Domain (NCBI)POU5F2
DMDM Disease mutations134187
Blocks (Seattle)POU5F2
SuperfamilyQ8N7G0
Human Protein AtlasENSG00000248483
Peptide AtlasQ8N7G0
HPRD08695
IPIIPI00171173   
Protein Interaction databases
DIP (DOE-UCLA)Q8N7G0
IntAct (EBI)Q8N7G0
FunCoupENSG00000248483
BioGRIDPOU5F2
STRING (EMBL)POU5F2
ZODIACPOU5F2
Ontologies - Pathways
QuickGOQ8N7G0
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  
NDEx NetworkPOU5F2
Atlas of Cancer Signalling NetworkPOU5F2
Wikipedia pathwaysPOU5F2
Orthology - Evolution
OrthoDB134187
GeneTree (enSembl)ENSG00000248483
Phylogenetic Trees/Animal Genes : TreeFamPOU5F2
HOVERGENQ8N7G0
HOGENOMQ8N7G0
Homologs : HomoloGenePOU5F2
Homology/Alignments : Family Browser (UCSC)POU5F2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOU5F2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POU5F2
dbVarPOU5F2
ClinVarPOU5F2
1000_GenomesPOU5F2 
Exome Variant ServerPOU5F2
ExAC (Exome Aggregation Consortium)POU5F2 (select the gene name)
Genetic variants : HAPMAP134187
Genomic Variants (DGV)POU5F2 [DGVbeta]
DECIPHERPOU5F2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOU5F2 
Mutations
ICGC Data PortalPOU5F2 
TCGA Data PortalPOU5F2 
Broad Tumor PortalPOU5F2
OASIS PortalPOU5F2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOU5F2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOU5F2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POU5F2
DgiDB (Drug Gene Interaction Database)POU5F2
DoCM (Curated mutations)POU5F2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POU5F2 (select a term)
intoGenPOU5F2
Cancer3DPOU5F2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPOU5F2
Genetic Testing Registry POU5F2
NextProtQ8N7G0 [Medical]
TSGene134187
GENETestsPOU5F2
Target ValidationPOU5F2
Huge Navigator POU5F2 [HugePedia]
snp3D : Map Gene to Disease134187
BioCentury BCIQPOU5F2
ClinGenPOU5F2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD134187
Chemical/Pharm GKB GenePA162399970
Clinical trialPOU5F2
Miscellaneous
canSAR (ICR)POU5F2 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOU5F2
EVEXPOU5F2
GoPubMedPOU5F2
iHOPPOU5F2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:58 CEST 2017

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