Atlas of Genetics and Cytogenetics in Oncology and Haematology


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POU6F1 (POU class 6 homeobox 1)

Identity

Alias_namesPOU domain
Alias_symbol (synonym)BRN5
MPOU
TCFB1
Other alias
HGNC (Hugo) POU6F1
LocusID (NCBI) 5463
Atlas_Id 51389
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 51580719 and ends at 51591950 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
POU6F1 (12q13.13) / QSOX1 (1q25.2)POU6F1 (12q13.13) / SMAGP (12q13.13)POU6F1 12q13.13 / SMAGP 12q13.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POU6F1   9224
Cards
Entrez_Gene (NCBI)POU6F1  5463  POU class 6 homeobox 1
AliasesBRN5; MPOU; TCFB1
GeneCards (Weizmann)POU6F1
Ensembl hg19 (Hinxton)ENSG00000184271 [Gene_View]  chr12:51580719-51591950 [Contig_View]  POU6F1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000184271 [Gene_View]  chr12:51580719-51591950 [Contig_View]  POU6F1 [Vega]
ICGC DataPortalENSG00000184271
TCGA cBioPortalPOU6F1
AceView (NCBI)POU6F1
Genatlas (Paris)POU6F1
WikiGenes5463
SOURCE (Princeton)POU6F1
Genetics Home Reference (NIH)POU6F1
Genomic and cartography
GoldenPath hg19 (UCSC)POU6F1  -     chr12:51580719-51591950 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)POU6F1  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblPOU6F1 - 12q13.13 [CytoView hg19]  POU6F1 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIPOU6F1 [Mapview hg19]  POU6F1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI417271 AK095191 AL832881 AW445212 BC051326
RefSeq transcript (Entrez)NM_002702
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)POU6F1
Cluster EST : UnigeneHs.555886 [ NCBI ]
CGAP (NCI)Hs.555886
Alternative Splicing GalleryENSG00000184271
Gene ExpressionPOU6F1 [ NCBI-GEO ]   POU6F1 [ EBI - ARRAY_EXPRESS ]   POU6F1 [ SEEK ]   POU6F1 [ MEM ]
Gene Expression Viewer (FireBrowse)POU6F1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5463
GTEX Portal (Tissue expression)POU6F1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14863   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14863  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14863
Splice isoforms : SwissVarQ14863
PhosPhoSitePlusQ14863
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)    POU_1 (PS00035)    POU_2 (PS00465)    POU_3 (PS51179)   
Domains : Interpro (EBI)Homeobox_dom    Homeodomain-like    Lambda_DNA-bd_dom    POU    POU_dom   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Pou (PF00157)   
Domain families : Pfam (NCBI)pfam00046    pfam00157   
Domain families : Smart (EMBL)HOX (SM00389)  POU (SM00352)  
Conserved Domain (NCBI)POU6F1
DMDM Disease mutations5463
Blocks (Seattle)POU6F1
PDB (SRS)3D1N   
PDB (PDBSum)3D1N   
PDB (IMB)3D1N   
PDB (RSDB)3D1N   
Structural Biology KnowledgeBase3D1N   
SCOP (Structural Classification of Proteins)3D1N   
CATH (Classification of proteins structures)3D1N   
SuperfamilyQ14863
Human Protein AtlasENSG00000184271
Peptide AtlasQ14863
HPRD17883
IPIIPI00398955   IPI01023016   
Protein Interaction databases
DIP (DOE-UCLA)Q14863
IntAct (EBI)Q14863
FunCoupENSG00000184271
BioGRIDPOU6F1
STRING (EMBL)POU6F1
ZODIACPOU6F1
Ontologies - Pathways
QuickGOQ14863
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  brain development  heart development  muscle organ development  actin cytoskeleton  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  brain development  heart development  muscle organ development  actin cytoskeleton  
NDEx NetworkPOU6F1
Atlas of Cancer Signalling NetworkPOU6F1
Wikipedia pathwaysPOU6F1
Orthology - Evolution
OrthoDB5463
GeneTree (enSembl)ENSG00000184271
Phylogenetic Trees/Animal Genes : TreeFamPOU6F1
HOVERGENQ14863
HOGENOMQ14863
Homologs : HomoloGenePOU6F1
Homology/Alignments : Family Browser (UCSC)POU6F1
Gene fusions - Rearrangements
Fusion : MitelmanPOU6F1/SMAGP [12q13.13/12q13.13]  
Fusion: TCGAPOU6F1 12q13.13 SMAGP 12q13.13 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOU6F1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POU6F1
dbVarPOU6F1
ClinVarPOU6F1
1000_GenomesPOU6F1 
Exome Variant ServerPOU6F1
ExAC (Exome Aggregation Consortium)POU6F1 (select the gene name)
Genetic variants : HAPMAP5463
Genomic Variants (DGV)POU6F1 [DGVbeta]
DECIPHER (Syndromes)12:51580719-51591950  ENSG00000184271
CONAN: Copy Number AnalysisPOU6F1 
Mutations
ICGC Data PortalPOU6F1 
TCGA Data PortalPOU6F1 
Broad Tumor PortalPOU6F1
OASIS PortalPOU6F1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOU6F1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOU6F1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POU6F1
DgiDB (Drug Gene Interaction Database)POU6F1
DoCM (Curated mutations)POU6F1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POU6F1 (select a term)
intoGenPOU6F1
Cancer3DPOU6F1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPOU6F1
Genetic Testing Registry POU6F1
NextProtQ14863 [Medical]
TSGene5463
GENETestsPOU6F1
Huge Navigator POU6F1 [HugePedia]
snp3D : Map Gene to Disease5463
BioCentury BCIQPOU6F1
ClinGenPOU6F1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5463
Chemical/Pharm GKB GenePA33548
Clinical trialPOU6F1
Miscellaneous
canSAR (ICR)POU6F1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOU6F1
EVEXPOU6F1
GoPubMedPOU6F1
iHOPPOU6F1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:22:20 CET 2017

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