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PP2D1 (protein phosphatase 2C like domain containing 1)

Identity

Alias_namesC3orf48
chromosome 3 open reading frame 48
protein phosphatase 2C-like domain containing 1
Alias_symbol (synonym)FLJ25449
Other alias
HGNC (Hugo) PP2D1
LocusID (NCBI) 151649
Atlas_Id 72107
Location 3p24.3  [Link to chromosome band 3p24]
Location_base_pair Starts at 19985344 and ends at 20012273 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PP2D1   28406
Cards
Entrez_Gene (NCBI)PP2D1  151649  protein phosphatase 2C like domain containing 1
AliasesC3orf48
GeneCards (Weizmann)PP2D1
Ensembl hg19 (Hinxton)ENSG00000183977 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183977 [Gene_View]  chr3:19985344-20012273 [Contig_View]  PP2D1 [Vega]
ICGC DataPortalENSG00000183977
TCGA cBioPortalPP2D1
AceView (NCBI)PP2D1
Genatlas (Paris)PP2D1
WikiGenes151649
SOURCE (Princeton)PP2D1
Genetics Home Reference (NIH)PP2D1
Genomic and cartography
GoldenPath hg38 (UCSC)PP2D1  -     chr3:19985344-20012273 -  3p24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PP2D1  -     3p24.3   [Description]    (hg19-Feb_2009)
EnsemblPP2D1 - 3p24.3 [CytoView hg19]  PP2D1 - 3p24.3 [CytoView hg38]
Mapping of homologs : NCBIPP2D1 [Mapview hg19]  PP2D1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK058178 BC021717 BC105097 BC105099 BI463522
RefSeq transcript (Entrez)NM_001252657 NM_144714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PP2D1
Cluster EST : UnigeneHs.733161 [ NCBI ]
CGAP (NCI)Hs.733161
Alternative Splicing GalleryENSG00000183977
Gene ExpressionPP2D1 [ NCBI-GEO ]   PP2D1 [ EBI - ARRAY_EXPRESS ]   PP2D1 [ SEEK ]   PP2D1 [ MEM ]
Gene Expression Viewer (FireBrowse)PP2D1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151649
GTEX Portal (Tissue expression)PP2D1
Human Protein AtlasENSG00000183977-PP2D1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8MPX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8MPX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8MPX8
Splice isoforms : SwissVarA8MPX8
PhosPhoSitePlusA8MPX8
Domaine pattern : Prosite (Expaxy)PPM_2 (PS51746)   
Domains : Interpro (EBI)PP2C    PPM-type_phosphatase_dom   
Domain families : Pfam (Sanger)PP2C (PF00481)   
Domain families : Pfam (NCBI)pfam00481   
Domain families : Smart (EMBL)PP2Cc (SM00332)  
Conserved Domain (NCBI)PP2D1
DMDM Disease mutations151649
Blocks (Seattle)PP2D1
SuperfamilyA8MPX8
Human Protein Atlas [tissue]ENSG00000183977-PP2D1 [tissue]
Peptide AtlasA8MPX8
HPRD08066
IPIIPI00871533   IPI00065055   IPI00784436   
Protein Interaction databases
DIP (DOE-UCLA)A8MPX8
IntAct (EBI)A8MPX8
FunCoupENSG00000183977
BioGRIDPP2D1
STRING (EMBL)PP2D1
ZODIACPP2D1
Ontologies - Pathways
QuickGOA8MPX8
Ontology : AmiGOprotein serine/threonine phosphatase activity  protein dephosphorylation  
Ontology : EGO-EBIprotein serine/threonine phosphatase activity  protein dephosphorylation  
NDEx NetworkPP2D1
Atlas of Cancer Signalling NetworkPP2D1
Wikipedia pathwaysPP2D1
Orthology - Evolution
OrthoDB151649
GeneTree (enSembl)ENSG00000183977
Phylogenetic Trees/Animal Genes : TreeFamPP2D1
HOVERGENA8MPX8
HOGENOMA8MPX8
Homologs : HomoloGenePP2D1
Homology/Alignments : Family Browser (UCSC)PP2D1
Gene fusions - Rearrangements
Tumor Fusion PortalPP2D1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPP2D1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PP2D1
dbVarPP2D1
ClinVarPP2D1
1000_GenomesPP2D1 
Exome Variant ServerPP2D1
ExAC (Exome Aggregation Consortium)ENSG00000183977
GNOMAD BrowserENSG00000183977
Genetic variants : HAPMAP151649
Genomic Variants (DGV)PP2D1 [DGVbeta]
DECIPHERPP2D1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPP2D1 
Mutations
ICGC Data PortalPP2D1 
TCGA Data PortalPP2D1 
Broad Tumor PortalPP2D1
OASIS PortalPP2D1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPP2D1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PP2D1
DgiDB (Drug Gene Interaction Database)PP2D1
DoCM (Curated mutations)PP2D1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PP2D1 (select a term)
intoGenPP2D1
Cancer3DPP2D1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPP2D1
MedgenPP2D1
Genetic Testing Registry PP2D1
NextProtA8MPX8 [Medical]
TSGene151649
GENETestsPP2D1
Target ValidationPP2D1
Huge Navigator PP2D1 [HugePedia]
snp3D : Map Gene to Disease151649
BioCentury BCIQPP2D1
ClinGenPP2D1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151649
Chemical/Pharm GKB GenePA143485325
Clinical trialPP2D1
Miscellaneous
canSAR (ICR)PP2D1 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePP2D1
EVEXPP2D1
GoPubMedPP2D1
iHOPPP2D1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:08:47 CET 2017

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