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PPAP2C (phosphatidic acid phosphatase type 2C)

Identity

Other aliasLPP2
PAP-2c
PAP2-g
HGNC (Hugo) PPAP2C
LocusID (NCBI) 8612
Atlas_Id 72111
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 281040 and ends at 291435 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPAP2C   9230
Cards
Entrez_Gene (NCBI)PPAP2C  8612  phosphatidic acid phosphatase type 2C
AliasesLPP2; PAP-2c; PAP2-g
GeneCards (Weizmann)PPAP2C
Ensembl hg19 (Hinxton)ENSG00000141934 [Gene_View]  chr19:281040-291435 [Contig_View]  PPAP2C [Vega]
Ensembl hg38 (Hinxton)ENSG00000141934 [Gene_View]  chr19:281040-291435 [Contig_View]  PPAP2C [Vega]
ICGC DataPortalENSG00000141934
TCGA cBioPortalPPAP2C
AceView (NCBI)PPAP2C
Genatlas (Paris)PPAP2C
WikiGenes8612
SOURCE (Princeton)PPAP2C
Genetics Home Reference (NIH)PPAP2C
Genomic and cartography
GoldenPath hg19 (UCSC)PPAP2C  -     chr19:281040-291435 -  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPAP2C  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblPPAP2C - 19p13.3 [CytoView hg19]  PPAP2C - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIPPAP2C [Mapview hg19]  PPAP2C [Mapview hg38]
OMIM607126   
Gene and transcription
Genbank (Entrez)AA428937 AB209696 AF035959 AF047760 AF056083
RefSeq transcript (Entrez)NM_003712 NM_177526 NM_177543
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)PPAP2C
Cluster EST : UnigeneHs.465506 [ NCBI ]
CGAP (NCI)Hs.465506
Alternative Splicing GalleryENSG00000141934
Gene ExpressionPPAP2C [ NCBI-GEO ]   PPAP2C [ EBI - ARRAY_EXPRESS ]   PPAP2C [ SEEK ]   PPAP2C [ MEM ]
Gene Expression Viewer (FireBrowse)PPAP2C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8612
GTEX Portal (Tissue expression)PPAP2C
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43688   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43688  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43688
Splice isoforms : SwissVarO43688
Catalytic activity : Enzyme3.1.3.4 [ Enzyme-Expasy ]   3.1.3.43.1.3.4 [ IntEnz-EBI ]   3.1.3.4 [ BRENDA ]   3.1.3.4 [ KEGG ]   
PhosPhoSitePlusO43688
Domains : Interpro (EBI)LPP2    P_Acid_Pase_2/haloperoxidase   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)PPAP2C
DMDM Disease mutations8612
Blocks (Seattle)PPAP2C
SuperfamilyO43688
Human Protein AtlasENSG00000141934
Peptide AtlasO43688
HPRD06180
IPIIPI00216620   IPI00334058   IPI00556105   IPI00376858   
Protein Interaction databases
DIP (DOE-UCLA)O43688
IntAct (EBI)O43688
FunCoupENSG00000141934
BioGRIDPPAP2C
STRING (EMBL)PPAP2C
ZODIACPPAP2C
Ontologies - Pathways
QuickGOO43688
Ontology : AmiGOphosphoprotein phosphatase activity  protein binding  plasma membrane  sphingolipid metabolic process  phosphatidate phosphatase activity  membrane  integral component of membrane  dephosphorylation  dephosphorylation  sphingolipid biosynthetic process  small molecule metabolic process  
Ontology : EGO-EBIphosphoprotein phosphatase activity  protein binding  plasma membrane  sphingolipid metabolic process  phosphatidate phosphatase activity  membrane  integral component of membrane  dephosphorylation  dephosphorylation  sphingolipid biosynthetic process  small molecule metabolic process  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism    Ether lipid metabolism    Sphingolipid metabolism    Fc gamma R-mediated phagocytosis    Fat digestion and absorption   
NDEx NetworkPPAP2C
Atlas of Cancer Signalling NetworkPPAP2C
Wikipedia pathwaysPPAP2C
Orthology - Evolution
OrthoDB8612
GeneTree (enSembl)ENSG00000141934
Phylogenetic Trees/Animal Genes : TreeFamPPAP2C
HOVERGENO43688
HOGENOMO43688
Homologs : HomoloGenePPAP2C
Homology/Alignments : Family Browser (UCSC)PPAP2C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPAP2C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPAP2C
dbVarPPAP2C
ClinVarPPAP2C
1000_GenomesPPAP2C 
Exome Variant ServerPPAP2C
ExAC (Exome Aggregation Consortium)PPAP2C (select the gene name)
Genetic variants : HAPMAP8612
Genomic Variants (DGV)PPAP2C [DGVbeta]
DECIPHER (Syndromes)19:281040-291435  ENSG00000141934
CONAN: Copy Number AnalysisPPAP2C 
Mutations
ICGC Data PortalPPAP2C 
TCGA Data PortalPPAP2C 
Broad Tumor PortalPPAP2C
OASIS PortalPPAP2C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPAP2C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPAP2C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPAP2C
DgiDB (Drug Gene Interaction Database)PPAP2C
DoCM (Curated mutations)PPAP2C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPAP2C (select a term)
intoGenPPAP2C
Cancer3DPPAP2C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607126   
Orphanet
MedgenPPAP2C
Genetic Testing Registry PPAP2C
NextProtO43688 [Medical]
TSGene8612
GENETestsPPAP2C
Huge Navigator PPAP2C [HugePedia]
snp3D : Map Gene to Disease8612
BioCentury BCIQPPAP2C
ClinGenPPAP2C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8612
Chemical/Pharm GKB GenePA33554
Clinical trialPPAP2C
Miscellaneous
canSAR (ICR)PPAP2C (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPAP2C
EVEXPPAP2C
GoPubMedPPAP2C
iHOPPPAP2C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:19 CET 2017

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