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PPAPDC1A (phosphatidic acid phosphatase type 2 domain containing 1A)

Identity

Other aliasDPPL2
PPAPDC1
HGNC (Hugo) PPAPDC1A
LocusID (NCBI) 196051
Atlas_Id 72112
Location 10q26.12  [Link to chromosome band 10q26]
Location_base_pair Starts at 122216466 and ends at 122349367 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DOCK1 PPAPDC1ARAPGEF5 PPAPDC1AMOBKL1A PPAPDC1A
SREBF2 PPAPDC1AC10orf88 PPAPDC1A

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPAPDC1A   23531
Cards
Entrez_Gene (NCBI)PPAPDC1A  196051  phosphatidic acid phosphatase type 2 domain containing 1A
AliasesDPPL2; PPAPDC1
GeneCards (Weizmann)PPAPDC1A
Ensembl hg19 (Hinxton)ENSG00000203805 [Gene_View]  chr10:122216466-122349367 [Contig_View]  PPAPDC1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000203805 [Gene_View]  chr10:122216466-122349367 [Contig_View]  PPAPDC1A [Vega]
ICGC DataPortalENSG00000203805
TCGA cBioPortalPPAPDC1A
AceView (NCBI)PPAPDC1A
Genatlas (Paris)PPAPDC1A
WikiGenes196051
SOURCE (Princeton)PPAPDC1A
Genetics Home Reference (NIH)PPAPDC1A
Genomic and cartography
GoldenPath hg19 (UCSC)PPAPDC1A  -     chr10:122216466-122349367 +  10q26.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPAPDC1A  -     10q26.12   [Description]    (hg38-Dec_2013)
EnsemblPPAPDC1A - 10q26.12 [CytoView hg19]  PPAPDC1A - 10q26.12 [CytoView hg38]
Mapping of homologs : NCBIPPAPDC1A [Mapview hg19]  PPAPDC1A [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK098668 AK296273 AK310178 BC101267 BC101268
RefSeq transcript (Entrez)NM_001030059
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)PPAPDC1A
Cluster EST : UnigeneHs.40479 [ NCBI ]
CGAP (NCI)Hs.40479
Alternative Splicing GalleryENSG00000203805
Gene ExpressionPPAPDC1A [ NCBI-GEO ]   PPAPDC1A [ EBI - ARRAY_EXPRESS ]   PPAPDC1A [ SEEK ]   PPAPDC1A [ MEM ]
Gene Expression Viewer (FireBrowse)PPAPDC1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)196051
GTEX Portal (Tissue expression)PPAPDC1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VZY2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VZY2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VZY2
Splice isoforms : SwissVarQ5VZY2
Catalytic activity : Enzyme3.1.3.4 [ Enzyme-Expasy ]   3.1.3.43.1.3.4 [ IntEnz-EBI ]   3.1.3.4 [ BRENDA ]   3.1.3.4 [ KEGG ]   
PhosPhoSitePlusQ5VZY2
Domains : Interpro (EBI)P_Acid_Pase_2/haloperoxidase    PPAPDC1A/PPAPDC1B   
Domain families : Pfam (Sanger)PAP2 (PF01569)   
Domain families : Pfam (NCBI)pfam01569   
Domain families : Smart (EMBL)acidPPc (SM00014)  
Conserved Domain (NCBI)PPAPDC1A
DMDM Disease mutations196051
Blocks (Seattle)PPAPDC1A
SuperfamilyQ5VZY2
Human Protein AtlasENSG00000203805
Peptide AtlasQ5VZY2
HPRD18745
IPIIPI00151444   IPI00845503   IPI00845417   IPI00922450   IPI00646785   
Protein Interaction databases
DIP (DOE-UCLA)Q5VZY2
IntAct (EBI)Q5VZY2
FunCoupENSG00000203805
BioGRIDPPAPDC1A
STRING (EMBL)PPAPDC1A
ZODIACPPAPDC1A
Ontologies - Pathways
QuickGOQ5VZY2
Ontology : AmiGOplasma membrane  phosphatidate phosphatase activity  integral component of membrane  Fc-gamma receptor signaling pathway involved in phagocytosis  innate immune response  phospholipid dephosphorylation  
Ontology : EGO-EBIplasma membrane  phosphatidate phosphatase activity  integral component of membrane  Fc-gamma receptor signaling pathway involved in phagocytosis  innate immune response  phospholipid dephosphorylation  
NDEx NetworkPPAPDC1A
Atlas of Cancer Signalling NetworkPPAPDC1A
Wikipedia pathwaysPPAPDC1A
Orthology - Evolution
OrthoDB196051
GeneTree (enSembl)ENSG00000203805
Phylogenetic Trees/Animal Genes : TreeFamPPAPDC1A
HOVERGENQ5VZY2
HOGENOMQ5VZY2
Homologs : HomoloGenePPAPDC1A
Homology/Alignments : Family Browser (UCSC)PPAPDC1A
Gene fusions - Rearrangements
Fusion: TCGADOCK1 PPAPDC1A
Fusion: TCGARAPGEF5 PPAPDC1A
Fusion: TCGAMOBKL1A PPAPDC1A
Fusion: TCGASREBF2 PPAPDC1A
Fusion: TCGAC10orf88 PPAPDC1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPAPDC1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPAPDC1A
dbVarPPAPDC1A
ClinVarPPAPDC1A
1000_GenomesPPAPDC1A 
Exome Variant ServerPPAPDC1A
ExAC (Exome Aggregation Consortium)PPAPDC1A (select the gene name)
Genetic variants : HAPMAP196051
Genomic Variants (DGV)PPAPDC1A [DGVbeta]
DECIPHER (Syndromes)10:122216466-122349367  ENSG00000203805
CONAN: Copy Number AnalysisPPAPDC1A 
Mutations
ICGC Data PortalPPAPDC1A 
TCGA Data PortalPPAPDC1A 
Broad Tumor PortalPPAPDC1A
OASIS PortalPPAPDC1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPAPDC1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPAPDC1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPAPDC1A
DgiDB (Drug Gene Interaction Database)PPAPDC1A
DoCM (Curated mutations)PPAPDC1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPAPDC1A (select a term)
intoGenPPAPDC1A
Cancer3DPPAPDC1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPPAPDC1A
Genetic Testing Registry PPAPDC1A
NextProtQ5VZY2 [Medical]
TSGene196051
GENETestsPPAPDC1A
Huge Navigator PPAPDC1A [HugePedia]
snp3D : Map Gene to Disease196051
BioCentury BCIQPPAPDC1A
ClinGenPPAPDC1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD196051
Chemical/Pharm GKB GenePA134907381
Clinical trialPPAPDC1A
Miscellaneous
canSAR (ICR)PPAPDC1A (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPAPDC1A
EVEXPPAPDC1A
GoPubMedPPAPDC1A
iHOPPPAPDC1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:19 CET 2017

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