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PPBP (pro-platelet basic protein (chemokine (C-X-C motif) ligand 7))

Identity

Other namesB-TG1
Beta-TG
CTAP-III
CTAP3
CTAPIII
CXCL7
LA-PF4
LDGF
MDGF
NAP-2
PBP
SCYB7
TC1
TC2
TGB
TGB1
THBGB
THBGB1
HGNC (Hugo) PPBP
LocusID (NCBI) 5473
Location 4q13.3
Location_base_pair Starts at 74852156 and ends at 74853907 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)PPBP   9240
Cards
Entrez_Gene (NCBI)PPBP  5473  pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
GeneCards (Weizmann)PPBP
Ensembl (Hinxton) [Gene_View]  chr4:74852156-74853907 [Contig_View]  PPBP [Vega]
cBioPortalPPBP
AceView (NCBI)PPBP
Genatlas (Paris)PPBP
WikiGenes5473
SOURCE (Princeton)NM_002704
Genomic and cartography
GoldenPath (UCSC)PPBP  -  4q13.3   chr4:74852156-74853907 -  4q13.3   [Description]    (hg19-Feb_2009)
EnsemblPPBP - 4q13.3 [CytoView]
Mapping of homologs : NCBIPPBP [Mapview]
OMIM121010   
Gene and transcription
Genbank (Entrez)AK312166 BC028217 BQ447470 BX443846 CB112845
RefSeq transcript (Entrez)NM_002704
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838914 NW_004929320
Consensus coding sequences : CCDS (NCBI)PPBP
Cluster EST : UnigeneHs.2164 [ NCBI ]
CGAP (NCI)Hs.2164
Alternative Splicing : Fast-db (Paris)GSHG0023317
Gene ExpressionPPBP [ NCBI-GEO ]     PPBP [ SEEK ]   PPBP [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02775 (Uniprot)
NextProtP02775  [Medical]
With graphics : InterProP02775
Splice isoforms : SwissVarP02775 (Swissvar)
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CXC (PS00471)   
Domains : Interpro (EBI)Chemokine_CXC [organisation]   Chemokine_CXC_CS [organisation]   Chemokine_IL8-like_dom [organisation]  
Related proteins : CluSTrP02775
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
DMDM Disease mutations5473
Blocks (Seattle)P02775
PDB (SRS)1F9P    1NAP    1TVX   
PDB (PDBSum)1F9P    1NAP    1TVX   
PDB (IMB)1F9P    1NAP    1TVX   
PDB (RSDB)1F9P    1NAP    1TVX   
Peptide AtlasP02775
HPRD07171
IPIIPI00022445   
Protein Interaction databases
DIP (DOE-UCLA)P02775
IntAct (EBI)P02775
BioGRIDPPBP
InParanoidP02775
Interologous Interaction database P02775
IntegromeDBPPBP
STRING (EMBL)PPBP
Ontologies - Pathways
Ontology : AmiGOplatelet degranulation  glucose transmembrane transporter activity  extracellular region  extracellular space  immune response  blood coagulation  chemokine activity  growth factor activity  glucose transport  platelet activation  platelet alpha granule lumen  defense response to bacterium  positive regulation of cell division  cell chemotaxis  
Ontology : EGO-EBIplatelet degranulation  glucose transmembrane transporter activity  extracellular region  extracellular space  immune response  blood coagulation  chemokine activity  growth factor activity  glucose transport  platelet activation  platelet alpha granule lumen  defense response to bacterium  positive regulation of cell division  cell chemotaxis  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
Protein Interaction DatabasePPBP
Wikipedia pathwaysPPBP
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PPBP
snp3D : Map Gene to Disease5473
SNP (GeneSNP Utah)PPBP
SNP : HGBasePPBP
Genetic variants : HAPMAPPPBP
Exome VariantPPBP
1000_GenomesPPBP 
Somatic Mutations in Cancer : COSMICPPBP 
CONAN: Copy Number AnalysisPPBP 
Mutations and Diseases : HGMDPPBP
Genomic VariantsPPBP  PPBP [DGVbeta]
dbVarPPBP
ClinVarPPBP
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM121010   
MedgenPPBP
GENETestsPPBP
Disease Genetic AssociationPPBP
Huge Navigator PPBP [HugePedia]  PPBP [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePPBP
Homology/Alignments : Family Browser (UCSC)PPBP
Phylogenetic Trees/Animal Genes : TreeFamPPBP
Chemical/Protein Interactions : CTD5473
Chemical/Pharm GKB GenePA33561
Clinical trialPPBP
Other databases
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
CoreMinePPBP
iHOPPPBP
OncoSearchPPBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:43:55 CEST 2014

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