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PPCS (phosphopantothenoylcysteine synthetase)

Identity

Alias_symbol (synonym)FLJ11838
Other alias-
HGNC (Hugo) PPCS
LocusID (NCBI) 79717
Atlas_Id 40593
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 42456494 and ends at 42461230 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPCS (1p34.2) / CCDC30 (1p34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPCS   25686
Cards
Entrez_Gene (NCBI)PPCS  79717  phosphopantothenoylcysteine synthetase
Aliases
GeneCards (Weizmann)PPCS
Ensembl hg19 (Hinxton)ENSG00000127125 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127125 [Gene_View]  chr1:42456494-42461230 [Contig_View]  PPCS [Vega]
ICGC DataPortalENSG00000127125
TCGA cBioPortalPPCS
AceView (NCBI)PPCS
Genatlas (Paris)PPCS
WikiGenes79717
SOURCE (Princeton)PPCS
Genetics Home Reference (NIH)PPCS
Genomic and cartography
GoldenPath hg38 (UCSC)PPCS  -     chr1:42456494-42461230 +  1p34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPCS  -     1p34.2   [Description]    (hg19-Feb_2009)
EnsemblPPCS - 1p34.2 [CytoView hg19]  PPCS - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBIPPCS [Mapview hg19]  PPCS [Mapview hg38]
OMIM609853   
Gene and transcription
Genbank (Entrez)AA748446 AK021900 BC012383 BC062586 BC104938
RefSeq transcript (Entrez)NM_001077447 NM_001287506 NM_001287507 NM_001287508 NM_001287509 NM_001287510 NM_001287511 NM_024664
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPCS
Cluster EST : UnigeneHs.706662 [ NCBI ]
CGAP (NCI)Hs.706662
Alternative Splicing GalleryENSG00000127125
Gene ExpressionPPCS [ NCBI-GEO ]   PPCS [ EBI - ARRAY_EXPRESS ]   PPCS [ SEEK ]   PPCS [ MEM ]
Gene Expression Viewer (FireBrowse)PPCS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79717
GTEX Portal (Tissue expression)PPCS
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAB8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAB8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAB8
Splice isoforms : SwissVarQ9HAB8
Catalytic activity : Enzyme6.3.2.5 [ Enzyme-Expasy ]   6.3.2.56.3.2.5 [ IntEnz-EBI ]   6.3.2.5 [ BRENDA ]   6.3.2.5 [ KEGG ]   
PhosPhoSitePlusQ9HAB8
Domains : Interpro (EBI)DNA/pantothenate-metab_flavo_C   
Domain families : Pfam (Sanger)DFP (PF04127)   
Domain families : Pfam (NCBI)pfam04127   
Conserved Domain (NCBI)PPCS
DMDM Disease mutations79717
Blocks (Seattle)PPCS
PDB (SRS)1P9O   
PDB (PDBSum)1P9O   
PDB (IMB)1P9O   
PDB (RSDB)1P9O   
Structural Biology KnowledgeBase1P9O   
SCOP (Structural Classification of Proteins)1P9O   
CATH (Classification of proteins structures)1P9O   
SuperfamilyQ9HAB8
Human Protein AtlasENSG00000127125
Peptide AtlasQ9HAB8
HPRD07760
IPIIPI00023987   IPI00479071   IPI00640962   IPI00645349   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAB8
IntAct (EBI)Q9HAB8
FunCoupENSG00000127125
BioGRIDPPCS
STRING (EMBL)PPCS
ZODIACPPCS
Ontologies - Pathways
QuickGOQ9HAB8
Ontology : AmiGOphosphopantothenate--cysteine ligase activity  phosphopantothenate--cysteine ligase activity  cytosol  coenzyme biosynthetic process  coenzyme A biosynthetic process  coenzyme A biosynthetic process  extracellular exosome  
Ontology : EGO-EBIphosphopantothenate--cysteine ligase activity  phosphopantothenate--cysteine ligase activity  cytosol  coenzyme biosynthetic process  coenzyme A biosynthetic process  coenzyme A biosynthetic process  extracellular exosome  
Pathways : KEGGPantothenate and CoA biosynthesis   
NDEx NetworkPPCS
Atlas of Cancer Signalling NetworkPPCS
Wikipedia pathwaysPPCS
Orthology - Evolution
OrthoDB79717
GeneTree (enSembl)ENSG00000127125
Phylogenetic Trees/Animal Genes : TreeFamPPCS
HOVERGENQ9HAB8
HOGENOMQ9HAB8
Homologs : HomoloGenePPCS
Homology/Alignments : Family Browser (UCSC)PPCS
Gene fusions - Rearrangements
Fusion : MitelmanPPCS/CCDC30 [1p34.2/1p34.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPCS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPCS
dbVarPPCS
ClinVarPPCS
1000_GenomesPPCS 
Exome Variant ServerPPCS
ExAC (Exome Aggregation Consortium)PPCS (select the gene name)
Genetic variants : HAPMAP79717
Genomic Variants (DGV)PPCS [DGVbeta]
DECIPHERPPCS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPCS 
Mutations
ICGC Data PortalPPCS 
TCGA Data PortalPPCS 
Broad Tumor PortalPPCS
OASIS PortalPPCS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPCS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPCS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPCS
DgiDB (Drug Gene Interaction Database)PPCS
DoCM (Curated mutations)PPCS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPCS (select a term)
intoGenPPCS
Cancer3DPPCS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609853   
Orphanet
MedgenPPCS
Genetic Testing Registry PPCS
NextProtQ9HAB8 [Medical]
TSGene79717
GENETestsPPCS
Target ValidationPPCS
Huge Navigator PPCS [HugePedia]
snp3D : Map Gene to Disease79717
BioCentury BCIQPPCS
ClinGenPPCS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79717
Chemical/Pharm GKB GenePA142671158
Clinical trialPPCS
Miscellaneous
canSAR (ICR)PPCS (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPCS
EVEXPPCS
GoPubMedPPCS
iHOPPPCS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:25:51 CEST 2017

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