PPEF1 (protein phosphatase, EF-hand calcium binding domain 1)

Identity

Other names	PP7
	PPEF
	PPP7C
HGNC	PPEF1
Location	Xp22
Location_base_pair	Starts at 18618966 and ends at 18755955 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PPEF1   9243
Entrez_Gene	PPEF1  5475  protein phosphatase, EF-hand calcium binding domain 1
	Cards
GeneCards	PPEF1
Ensembl	PPEF1 [Search_View]   ENSG00000086717 [Gene_View]
Genatlas	PPEF1
GeneLynx	PPEF1
eGenome	PPEF1
euGene	5475
	Genomic and cartography
GoldenPath	PPEF1  -  Xp22   chrX:18618966-18755955 +  Xp22.13   [Description]    (hg18-March_2006)
Ensembl	PPEF1 - Xp22.13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PPEF1
	Gene and transcription
Genbank	AF023455 [ ENTREZ ]
Genbank	AF027977 [ ENTREZ ]
Genbank	AK290463 [ ENTREZ ]
Genbank	AK292235 [ ENTREZ ]
Genbank	AK315809 [ ENTREZ ]
RefSeq	NM_006240 [ SRS ]    NM_006240 [ ENTREZ ]
RefSeq	NM_152224 [ SRS ]    NM_152224 [ ENTREZ ]
RefSeq	NM_152226 [ SRS ]    NM_152226 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	AC_000155 [ SRS ]    AC_000155 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_011757 [ SRS ]    NT_011757 [ ENTREZ ]
RefSeq	NW_001842360 [ SRS ]    NW_001842360 [ ENTREZ ]
RefSeq	NW_927700 [ SRS ]    NW_927700 [ ENTREZ ]
AceView	PPEF1 AceView - NCBI
Unigene	Hs.211589 [ SRS ]    Hs.211589 [ NCBI ]     HS211589 [ spliceNest ]
Fast-db	2880 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14829 [ SRS]    O14829 [ EXPASY ]     O14829 [ INTERPRO ]     O14829 [ UNIPROT ]
Prosite	PS00018 EF_HAND_1 [ SRS ]    PS00018 EF_HAND_1 [ Expasy ]
Prosite	PS50222 EF_HAND_2 [ SRS ]    PS50222 EF_HAND_2 [ Expasy ]
Prosite	PS50096 IQ [ SRS ]    PS50096 IQ [ Expasy ]
Prosite	PS00125 SER_THR_PHOSPHATASE [ SRS ]    PS00125 SER_THR_PHOSPHATASE [ Expasy ]
Interpro	IPR011992 EF-Hand_type [ SRS ]    IPR011992 EF-Hand_type [ EBI ]
Interpro	IPR002048 EF_hand_Ca_bd [ SRS ]    IPR002048 EF_hand_Ca_bd [ EBI ]
Interpro	IPR000048 IQ_CaM_bd_region [ SRS ]    IPR000048 IQ_CaM_bd_region [ EBI ]
Interpro	IPR004843 M-pesterase [ SRS ]    IPR004843 M-pesterase [ EBI ]
Interpro	IPR012008 PPEF [ SRS ]    IPR012008 PPEF [ EBI ]
Interpro	IPR013235 PPP5 [ SRS ]    IPR013235 PPP5 [ EBI ]
Interpro	IPR006186 T_phtase_apaH [ SRS ]    IPR006186 T_phtase_apaH [ EBI ]
CluSTr	O14829
Pfam	PF00036 efhand [ SRS ]    PF00036 efhand [ Sanger ]    pfam00036 [ NCBI-CDD ]
Pfam	PF00612 IQ [ SRS ]    PF00612 IQ [ Sanger ]    pfam00612 [ NCBI-CDD ]
Pfam	PF00149 Metallophos [ SRS ]    PF00149 Metallophos [ Sanger ]    pfam00149 [ NCBI-CDD ]
Pfam	PF08321 PPP5 [ SRS ]    PF08321 PPP5 [ Sanger ]    pfam08321 [ NCBI-CDD ]
Smart	SM00054 EFh [EMBL]
Smart	SM00015 IQ [EMBL]
Smart	SM00156 PP2Ac [EMBL]
Prodom	PD000012 EF-hand[INRA-Toulouse]
Prodom	O14829 PPE1_HUMAN [ Domain structure ]   O14829 PPE1_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000012[INRA-Toulouse]
Prodom	O14829 PPE1_HUMAN [ Domain structure ]   O14829 PPE1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	O14829
HPRD	02118
	Protein Interaction databases
DIP	O14829
IntAct	O14829
	Polymorphism : SNP, mutations, diseases
OMIM	300109    [ map ]
GENECLINICS	300109
SNP	PPEF1 [dbSNP-NCBI]
SNP	NM_006240 [SNP-NCI]
SNP	NM_152224 [SNP-NCI]
SNP	NM_152226 [SNP-NCI]
SNP	PPEF1 [GeneSNPs - Utah]  PPEF1] [HGBASE - SRS]
HAPMAP	PPEF1 [HAPMAP]
COSMIC	PPEF1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PPEF1
	General knowledge
Family Browser	PPEF1 [UCSC Family Browser]
SOURCE	NM_006240
SOURCE	NM_152224
SOURCE	NM_152226
SMD	Hs.211589
SAGE	Hs.211589
Enzyme	3.1.3.16 [ Enzyme-Expasy ]   3.1.3.16 [ Enzyme-SRS ]   3.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   3.1.3.16 [ WIT ]
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	protein serine/threonine phosphatase activity [Amigo]  protein serine/threonine phosphatase activity
GO	iron ion binding [Amigo]  iron ion binding
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein amino acid dephosphorylation [Amigo]  protein amino acid dephosphorylation
GO	hydrolase activity [Amigo]  hydrolase activity
GO	manganese ion binding [Amigo]  manganese ion binding
GO	detection of stimulus involved in sensory perception [Amigo]  detection of stimulus involved in sensory perception
PubGene	PPEF1
TreeFam	PPEF1
CTD	5475 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PPEF1 Related clones (RZPD - Berlin)
	PubMed
PubMed	12 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:48:47 2008