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PPEF2 (protein phosphatase with EF-hand domain 2)

Identity

Alias_namescatalytic subunit
beta isozyme
Alias_symbol (synonym)PPP7CB
Other alias
HGNC (Hugo) PPEF2
LocusID (NCBI) 5470
Atlas_Id 46780
Location 4q21.1  [Link to chromosome band 4q21]
Location_base_pair Starts at 76781026 and ends at 76823681 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPEF2   9244
Cards
Entrez_Gene (NCBI)PPEF2  5470  protein phosphatase with EF-hand domain 2
AliasesPPP7CB
GeneCards (Weizmann)PPEF2
Ensembl hg19 (Hinxton)ENSG00000156194 [Gene_View]  chr4:76781026-76823681 [Contig_View]  PPEF2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000156194 [Gene_View]  chr4:76781026-76823681 [Contig_View]  PPEF2 [Vega]
ICGC DataPortalENSG00000156194
TCGA cBioPortalPPEF2
AceView (NCBI)PPEF2
Genatlas (Paris)PPEF2
WikiGenes5470
SOURCE (Princeton)PPEF2
Genetics Home Reference (NIH)PPEF2
Genomic and cartography
GoldenPath hg19 (UCSC)PPEF2  -     chr4:76781026-76823681 -  4q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPEF2  -     4q21.1   [Description]    (hg38-Dec_2013)
EnsemblPPEF2 - 4q21.1 [CytoView hg19]  PPEF2 - 4q21.1 [CytoView hg38]
Mapping of homologs : NCBIPPEF2 [Mapview hg19]  PPEF2 [Mapview hg38]
OMIM602256   
Gene and transcription
Genbank (Entrez)AF023456 AF023457 AL079280 BC113379 BC148514
RefSeq transcript (Entrez)NM_006239 NM_152933 NM_152934
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)PPEF2
Cluster EST : UnigeneHs.290873 [ NCBI ]
CGAP (NCI)Hs.290873
Alternative Splicing GalleryENSG00000156194
Gene ExpressionPPEF2 [ NCBI-GEO ]   PPEF2 [ EBI - ARRAY_EXPRESS ]   PPEF2 [ SEEK ]   PPEF2 [ MEM ]
Gene Expression Viewer (FireBrowse)PPEF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5470
GTEX Portal (Tissue expression)PPEF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14830   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14830  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14830
Splice isoforms : SwissVarO14830
PhosPhoSitePlusO14830
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    SER_THR_PHOSPHATASE (PS00125)   
Domains : Interpro (EBI)Calcineurin-like_PHP_apaH    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    IQ_motif_EF-hand-BS    Metallo-depent_PP-like    PPP_dom    Ser/Thr-Pase_EF-hand_contain    Ser/Thr-sp_prot-phosphatase   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)    Metallophos (PF00149)    PPP5 (PF08321)   
Domain families : Pfam (NCBI)pfam13499    pfam00149    pfam08321   
Domain families : Smart (EMBL)EFh (SM00054)  IQ (SM00015)  PP2Ac (SM00156)  
Conserved Domain (NCBI)PPEF2
DMDM Disease mutations5470
Blocks (Seattle)PPEF2
SuperfamilyO14830
Human Protein AtlasENSG00000156194
Peptide AtlasO14830
HPRD03771
IPIIPI00784130   IPI00395633   
Protein Interaction databases
DIP (DOE-UCLA)O14830
IntAct (EBI)O14830
FunCoupENSG00000156194
BioGRIDPPEF2
STRING (EMBL)PPEF2
ZODIACPPEF2
Ontologies - Pathways
QuickGOO14830
Ontology : AmiGOphotoreceptor outer segment  photoreceptor inner segment  protein serine/threonine phosphatase activity  iron ion binding  calcium ion binding  protein binding  cytoplasm  protein dephosphorylation  visual perception  negative regulation of peptidyl-threonine phosphorylation  manganese ion binding  Hsp70 protein binding  mitogen-activated protein kinase kinase kinase binding  regulation of MAP kinase activity  negative regulation of MAPK cascade  regulation of JUN kinase activity  detection of stimulus involved in sensory perception  Hsp90 protein binding  
Ontology : EGO-EBIphotoreceptor outer segment  photoreceptor inner segment  protein serine/threonine phosphatase activity  iron ion binding  calcium ion binding  protein binding  cytoplasm  protein dephosphorylation  visual perception  negative regulation of peptidyl-threonine phosphorylation  manganese ion binding  Hsp70 protein binding  mitogen-activated protein kinase kinase kinase binding  regulation of MAP kinase activity  negative regulation of MAPK cascade  regulation of JUN kinase activity  detection of stimulus involved in sensory perception  Hsp90 protein binding  
NDEx NetworkPPEF2
Atlas of Cancer Signalling NetworkPPEF2
Wikipedia pathwaysPPEF2
Orthology - Evolution
OrthoDB5470
GeneTree (enSembl)ENSG00000156194
Phylogenetic Trees/Animal Genes : TreeFamPPEF2
HOVERGENO14830
HOGENOMO14830
Homologs : HomoloGenePPEF2
Homology/Alignments : Family Browser (UCSC)PPEF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPEF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPEF2
dbVarPPEF2
ClinVarPPEF2
1000_GenomesPPEF2 
Exome Variant ServerPPEF2
ExAC (Exome Aggregation Consortium)PPEF2 (select the gene name)
Genetic variants : HAPMAP5470
Genomic Variants (DGV)PPEF2 [DGVbeta]
DECIPHER (Syndromes)4:76781026-76823681  ENSG00000156194
CONAN: Copy Number AnalysisPPEF2 
Mutations
ICGC Data PortalPPEF2 
TCGA Data PortalPPEF2 
Broad Tumor PortalPPEF2
OASIS PortalPPEF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPEF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPEF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPEF2
DgiDB (Drug Gene Interaction Database)PPEF2
DoCM (Curated mutations)PPEF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPEF2 (select a term)
intoGenPPEF2
Cancer3DPPEF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602256   
Orphanet
MedgenPPEF2
Genetic Testing Registry PPEF2
NextProtO14830 [Medical]
TSGene5470
GENETestsPPEF2
Huge Navigator PPEF2 [HugePedia]
snp3D : Map Gene to Disease5470
BioCentury BCIQPPEF2
ClinGenPPEF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5470
Chemical/Pharm GKB GenePA33565
Clinical trialPPEF2
Miscellaneous
canSAR (ICR)PPEF2 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPEF2
EVEXPPEF2
GoPubMedPPEF2
iHOPPPEF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:15:11 CEST 2017

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