PPFIA4 (PTPRF interacting protein alpha 4)

2007-04-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 8497
MIM: 603145
HGNC: 9248
Ensembl: ENSG00000143847

Variants:

dbSNP: 8497
ClinVar: 8497
TCGA: ENSG00000143847
COSMIC: PPFIA4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143847ENST00000272198O75335
ENSG00000143847ENST00000295706O75335
ENSG00000143847ENST00000367240B1APN9
ENSG00000143847ENST00000447715O75335
ENSG00000143847ENST00000599514M0R219
ENSG00000143847ENST00000599966O75335
ENSG00000143847ENST00000600426M0QZB5

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Release CycleREACTOMER-HSA-112310
Norepinephrine Neurotransmitter Release CycleREACTOMER-HSA-181430
Serotonin Neurotransmitter Release CycleREACTOMER-HSA-181429
Glutamate Neurotransmitter Release CycleREACTOMER-HSA-210500
Dopamine Neurotransmitter Release CycleREACTOMER-HSA-212676
Acetylcholine Neurotransmitter Release CycleREACTOMER-HSA-264642

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381821522023PPFIA4 Promotes Proliferation, Migration and Glycolysis of Esophageal Cancer Cells.0
381821522023PPFIA4 Promotes Proliferation, Migration and Glycolysis of Esophageal Cancer Cells.0
308421472019Liprin-α4 as a New Therapeutic Target for SCLC as an Upstream Mediator of HIF1α.4
308421472019Liprin-α4 as a New Therapeutic Target for SCLC as an Upstream Mediator of HIF1α.4
284600222017Korean atrial fibrillation network genome-wide association study for early-onset atrial fibrillation identifies novel susceptibility loci.34
291874402017Liprin-α4 as a Possible New Therapeutic Target for Pancreatic Cancer.8
284600222017Korean atrial fibrillation network genome-wide association study for early-onset atrial fibrillation identifies novel susceptibility loci.34
291874402017Liprin-α4 as a Possible New Therapeutic Target for Pancreatic Cancer.8
218296492011Liprin-α4 is required for nickel induced receptor protein tyrosine phosphatase-leukocyte antigen related receptor F (RPTP-LAR) activity.2
218296492011Liprin-α4 is required for nickel induced receptor protein tyrosine phosphatase-leukocyte antigen related receptor F (RPTP-LAR) activity.2
205999432010Liprin-α4 is a new hypoxia-inducible target gene required for maintenance of cell-cell contacts.12
205999432010Liprin-α4 is a new hypoxia-inducible target gene required for maintenance of cell-cell contacts.12
195361752009Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.32
195361752009Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.32

Citation

Dessen P

PPFIA4 (PTPRF interacting protein alpha 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46762/ppfia4