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PPFIA4 (PTPRF interacting protein alpha 4)

Identity

Alias_namesprotein tyrosine phosphatase
Other alias-
HGNC (Hugo) PPFIA4
LocusID (NCBI) 8497
Atlas_Id 46762
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 203026521 and ends at 203078736 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPFIA4 (1q32.1) / SYT2 (1q32.1)SYT2 (1q32.1) / PPFIA4 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPFIA4   9248
Cards
Entrez_Gene (NCBI)PPFIA4  8497  PTPRF interacting protein alpha 4
Aliases
GeneCards (Weizmann)PPFIA4
Ensembl hg19 (Hinxton)ENSG00000143847 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143847 [Gene_View]  chr1:203026521-203078736 [Contig_View]  PPFIA4 [Vega]
ICGC DataPortalENSG00000143847
TCGA cBioPortalPPFIA4
AceView (NCBI)PPFIA4
Genatlas (Paris)PPFIA4
WikiGenes8497
SOURCE (Princeton)PPFIA4
Genetics Home Reference (NIH)PPFIA4
Genomic and cartography
GoldenPath hg38 (UCSC)PPFIA4  -     chr1:203026521-203078736 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPFIA4  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblPPFIA4 - 1q32.1 [CytoView hg19]  PPFIA4 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIPPFIA4 [Mapview hg19]  PPFIA4 [Mapview hg38]
OMIM603145   
Gene and transcription
Genbank (Entrez)AB020704 AF034801 AI341415 AK023365 AK124535
RefSeq transcript (Entrez)NM_001304331 NM_001304332 NM_015053
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPFIA4
Cluster EST : UnigeneHs.730047 [ NCBI ]
CGAP (NCI)Hs.730047
Alternative Splicing GalleryENSG00000143847
Gene ExpressionPPFIA4 [ NCBI-GEO ]   PPFIA4 [ EBI - ARRAY_EXPRESS ]   PPFIA4 [ SEEK ]   PPFIA4 [ MEM ]
Gene Expression Viewer (FireBrowse)PPFIA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8497
GTEX Portal (Tissue expression)PPFIA4
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75335   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75335  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75335
Splice isoforms : SwissVarO75335
PhosPhoSitePlusO75335
Domaine pattern : Prosite (Expaxy)SAM_DOMAIN (PS50105)   
Domains : Interpro (EBI)Liprin    PPFIA4    SAM    SAM/pointed   
Domain families : Pfam (Sanger)SAM_1 (PF00536)    SAM_2 (PF07647)   
Domain families : Pfam (NCBI)pfam00536    pfam07647   
Domain families : Smart (EMBL)SAM (SM00454)  
Conserved Domain (NCBI)PPFIA4
DMDM Disease mutations8497
Blocks (Seattle)PPFIA4
SuperfamilyO75335
Human Protein AtlasENSG00000143847
Peptide AtlasO75335
HPRD16012
IPIIPI00916144   IPI00397579   IPI00910122   IPI00397578   IPI00642161   
Protein Interaction databases
DIP (DOE-UCLA)O75335
IntAct (EBI)O75335
FunCoupENSG00000143847
BioGRIDPPFIA4
STRING (EMBL)PPFIA4
ZODIACPPFIA4
Ontologies - Pathways
QuickGOO75335
Ontology : AmiGOprotein binding  intracellular  cytosol  neurotransmitter secretion  cell surface  glutamate secretion  synapse  presynaptic active zone  
Ontology : EGO-EBIprotein binding  intracellular  cytosol  neurotransmitter secretion  cell surface  glutamate secretion  synapse  presynaptic active zone  
NDEx NetworkPPFIA4
Atlas of Cancer Signalling NetworkPPFIA4
Wikipedia pathwaysPPFIA4
Orthology - Evolution
OrthoDB8497
GeneTree (enSembl)ENSG00000143847
Phylogenetic Trees/Animal Genes : TreeFamPPFIA4
HOVERGENO75335
HOGENOMO75335
Homologs : HomoloGenePPFIA4
Homology/Alignments : Family Browser (UCSC)PPFIA4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPFIA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPFIA4
dbVarPPFIA4
ClinVarPPFIA4
1000_GenomesPPFIA4 
Exome Variant ServerPPFIA4
ExAC (Exome Aggregation Consortium)PPFIA4 (select the gene name)
Genetic variants : HAPMAP8497
Genomic Variants (DGV)PPFIA4 [DGVbeta]
DECIPHERPPFIA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPFIA4 
Mutations
ICGC Data PortalPPFIA4 
TCGA Data PortalPPFIA4 
Broad Tumor PortalPPFIA4
OASIS PortalPPFIA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPFIA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPFIA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPFIA4
DgiDB (Drug Gene Interaction Database)PPFIA4
DoCM (Curated mutations)PPFIA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPFIA4 (select a term)
intoGenPPFIA4
Cancer3DPPFIA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603145   
Orphanet
MedgenPPFIA4
Genetic Testing Registry PPFIA4
NextProtO75335 [Medical]
TSGene8497
GENETestsPPFIA4
Target ValidationPPFIA4
Huge Navigator PPFIA4 [HugePedia]
snp3D : Map Gene to Disease8497
BioCentury BCIQPPFIA4
ClinGenPPFIA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8497
Chemical/Pharm GKB GenePA33569
Clinical trialPPFIA4
Miscellaneous
canSAR (ICR)PPFIA4 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPFIA4
EVEXPPFIA4
GoPubMedPPFIA4
iHOPPPFIA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:04:00 CEST 2017

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