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PPIG (peptidylprolyl isomerase G (cyclophilin G))

Identity

Alias_symbol (synonym)CARS-Cyp
SRCyp
SCAF10
Other aliasCYP
HGNC (Hugo) PPIG
LocusID (NCBI) 9360
Atlas_Id 72131
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 170440850 and ends at 170494254 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HLA-DRA (6p21.32) / PPIG (2q31.1)KIF21B (1q32.1) / PPIG (2q31.1)PPIG (2q31.1) / ARHGAP12 (10p11.22)
PPIG (2q31.1) / CASP8AP2 (6q15)PPIG (2q31.1) / CRIM1 (2p22.3)PPIG (2q31.1) / PPIG (2q31.1)
PPIG (2q31.1) / SPATA5 (4q28.1)PPIG (2q31.1) / SRSF5 (14q24.2)STIM2 (4p15.2) / PPIG (2q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPIG   14650
Cards
Entrez_Gene (NCBI)PPIG  9360  peptidylprolyl isomerase G (cyclophilin G)
AliasesCARS-Cyp; CYP; SCAF10; SRCyp
GeneCards (Weizmann)PPIG
Ensembl hg19 (Hinxton)ENSG00000138398 [Gene_View]  chr2:170440850-170494254 [Contig_View]  PPIG [Vega]
Ensembl hg38 (Hinxton)ENSG00000138398 [Gene_View]  chr2:170440850-170494254 [Contig_View]  PPIG [Vega]
ICGC DataPortalENSG00000138398
TCGA cBioPortalPPIG
AceView (NCBI)PPIG
Genatlas (Paris)PPIG
WikiGenes9360
SOURCE (Princeton)PPIG
Genetics Home Reference (NIH)PPIG
Genomic and cartography
GoldenPath hg19 (UCSC)PPIG  -     chr2:170440850-170494254 +  2q31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPIG  -     2q31.1   [Description]    (hg38-Dec_2013)
EnsemblPPIG - 2q31.1 [CytoView hg19]  PPIG - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIPPIG [Mapview hg19]  PPIG [Mapview hg38]
OMIM606093   
Gene and transcription
Genbank (Entrez)AK124958 AK307552 BC001555 BC063711 BC073875
RefSeq transcript (Entrez)NM_004792
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)PPIG
Cluster EST : UnigeneHs.593163 [ NCBI ]
CGAP (NCI)Hs.593163
Alternative Splicing GalleryENSG00000138398
Gene ExpressionPPIG [ NCBI-GEO ]   PPIG [ EBI - ARRAY_EXPRESS ]   PPIG [ SEEK ]   PPIG [ MEM ]
Gene Expression Viewer (FireBrowse)PPIG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9360
GTEX Portal (Tissue expression)PPIG
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13427   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13427  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13427
Splice isoforms : SwissVarQ13427
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
PhosPhoSitePlusQ13427
Domaine pattern : Prosite (Expaxy)CSA_PPIASE_1 (PS00170)    CSA_PPIASE_2 (PS50072)   
Domains : Interpro (EBI)Cyclophilin-like_dom    Cyclophilin-type_PPIase    Cyclophilin-type_PPIase_CS    Cyclophilin-type_PPIase_dom   
Domain families : Pfam (Sanger)Pro_isomerase (PF00160)   
Domain families : Pfam (NCBI)pfam00160   
Conserved Domain (NCBI)PPIG
DMDM Disease mutations9360
Blocks (Seattle)PPIG
PDB (SRS)2GW2    2WFI    2WFJ   
PDB (PDBSum)2GW2    2WFI    2WFJ   
PDB (IMB)2GW2    2WFI    2WFJ   
PDB (RSDB)2GW2    2WFI    2WFJ   
Structural Biology KnowledgeBase2GW2    2WFI    2WFJ   
SCOP (Structural Classification of Proteins)2GW2    2WFI    2WFJ   
CATH (Classification of proteins structures)2GW2    2WFI    2WFJ   
SuperfamilyQ13427
Human Protein AtlasENSG00000138398
Peptide AtlasQ13427
HPRD12083
IPIIPI00006298   IPI00409624   IPI01014703   IPI00917609   IPI00917908   IPI00917752   IPI00916005   
Protein Interaction databases
DIP (DOE-UCLA)Q13427
IntAct (EBI)Q13427
FunCoupENSG00000138398
BioGRIDPPIG
STRING (EMBL)PPIG
ZODIACPPIG
Ontologies - Pathways
QuickGOQ13427
Ontology : AmiGOprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  protein binding  nucleus  nucleoplasm  cytoplasm  protein folding  RNA splicing  cyclosporin A binding  nuclear matrix  nuclear speck  poly(A) RNA binding  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  protein binding  nucleus  nucleoplasm  cytoplasm  protein folding  RNA splicing  cyclosporin A binding  nuclear matrix  nuclear speck  poly(A) RNA binding  
NDEx NetworkPPIG
Atlas of Cancer Signalling NetworkPPIG
Wikipedia pathwaysPPIG
Orthology - Evolution
OrthoDB9360
GeneTree (enSembl)ENSG00000138398
Phylogenetic Trees/Animal Genes : TreeFamPPIG
HOVERGENQ13427
HOGENOMQ13427
Homologs : HomoloGenePPIG
Homology/Alignments : Family Browser (UCSC)PPIG
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPIG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPIG
dbVarPPIG
ClinVarPPIG
1000_GenomesPPIG 
Exome Variant ServerPPIG
ExAC (Exome Aggregation Consortium)PPIG (select the gene name)
Genetic variants : HAPMAP9360
Genomic Variants (DGV)PPIG [DGVbeta]
DECIPHER (Syndromes)2:170440850-170494254  ENSG00000138398
CONAN: Copy Number AnalysisPPIG 
Mutations
ICGC Data PortalPPIG 
TCGA Data PortalPPIG 
Broad Tumor PortalPPIG
OASIS PortalPPIG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPIG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPIG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPIG
DgiDB (Drug Gene Interaction Database)PPIG
DoCM (Curated mutations)PPIG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPIG (select a term)
intoGenPPIG
Cancer3DPPIG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606093   
Orphanet
MedgenPPIG
Genetic Testing Registry PPIG
NextProtQ13427 [Medical]
TSGene9360
GENETestsPPIG
Huge Navigator PPIG [HugePedia]
snp3D : Map Gene to Disease9360
BioCentury BCIQPPIG
ClinGenPPIG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9360
Chemical/Pharm GKB GenePA33585
Clinical trialPPIG
Miscellaneous
canSAR (ICR)PPIG (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPIG
EVEXPPIG
GoPubMedPPIG
iHOPPPIG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:39:22 CET 2017

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