PPIL1 (peptidylprolyl isomerase like 1)

2016-10-01  

Identity

HGNC
PPIL1
LOCATION
6p21.2
LOCUSID
51645
ALIAS
CGI-124,CYPL1,PCH14,PPIase,hCyPX
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51645
MIM: 601301
HGNC: 9260
Ensembl: ENSG00000137168

Variants:

dbSNP: 51645
ClinVar: 51645
TCGA: ENSG00000137168
COSMIC: PPIL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137168ENST00000373699Q9Y3C6
ENSG00000137168ENST00000373699A0A024RCX8

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, 35S U5-snRNPKEGGhsa_M00355
Spliceosome, 35S U5-snRNPKEGGM00355
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

References

Pubmed IDYearTitleCitations
165956882006Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP.17
200073192010A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR.14
203688032010The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein.8
157727612005Backbone and side chain assignments of human Peptidylprolyl Isomerase Like 1 (hPPIL1).0

Citation

Dessen P

PPIL1 (peptidylprolyl isomerase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55956/ppil1