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PPIL4 (peptidylprolyl isomerase like 4)

Identity

Alias_namespeptidylprolyl isomerase (cyclophilin)-like 4
Other aliasHDCME13P
HGNC (Hugo) PPIL4
LocusID (NCBI) 85313
Atlas_Id 72134
Location 6q25.1  [Link to chromosome band 6q25]
Location_base_pair Starts at 149504495 and ends at 149546102 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NCOA6 (20q11.22) / PPIL4 (6q25.1)PPIL4 (6q25.1) / KATNA1 (6q25.1)PPIL4 (6q25.1) / PPIL4 (6q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPIL4   15702
Cards
Entrez_Gene (NCBI)PPIL4  85313  peptidylprolyl isomerase like 4
AliasesHDCME13P
GeneCards (Weizmann)PPIL4
Ensembl hg19 (Hinxton)ENSG00000131013 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131013 [Gene_View]  ENSG00000131013 [Sequence]  chr6:149504495-149546102 [Contig_View]  PPIL4 [Vega]
ICGC DataPortalENSG00000131013
TCGA cBioPortalPPIL4
AceView (NCBI)PPIL4
Genatlas (Paris)PPIL4
WikiGenes85313
SOURCE (Princeton)PPIL4
Genetics Home Reference (NIH)PPIL4
Genomic and cartography
GoldenPath hg38 (UCSC)PPIL4  -     chr6:149504495-149546102 -  6q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPIL4  -     6q25.1   [Description]    (hg19-Feb_2009)
EnsemblPPIL4 - 6q25.1 [CytoView hg19]  PPIL4 - 6q25.1 [CytoView hg38]
Mapping of homologs : NCBIPPIL4 [Mapview hg19]  PPIL4 [Mapview hg38]
OMIM607609   
Gene and transcription
Genbank (Entrez)AF068298 AF308286 AF357880 AK092069 AK315388
RefSeq transcript (Entrez)NM_139126
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPIL4
Cluster EST : UnigeneHs.744238 [ NCBI ]
CGAP (NCI)Hs.744238
Alternative Splicing GalleryENSG00000131013
Gene ExpressionPPIL4 [ NCBI-GEO ]   PPIL4 [ EBI - ARRAY_EXPRESS ]   PPIL4 [ SEEK ]   PPIL4 [ MEM ]
Gene Expression Viewer (FireBrowse)PPIL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85313
GTEX Portal (Tissue expression)PPIL4
Human Protein AtlasENSG00000131013-PPIL4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUA2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUA2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUA2
Splice isoforms : SwissVarQ8WUA2
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
PhosPhoSitePlusQ8WUA2
Domaine pattern : Prosite (Expaxy)CSA_PPIASE_2 (PS50072)    RRM (PS50102)   
Domains : Interpro (EBI)Cyclophilin-like_dom    Cyclophilin-type_PPIase    Cyclophilin-type_PPIase_dom    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)Pro_isomerase (PF00160)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00160    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)PPIL4
DMDM Disease mutations85313
Blocks (Seattle)PPIL4
SuperfamilyQ8WUA2
Human Protein Atlas [tissue]ENSG00000131013-PPIL4 [tissue]
Peptide AtlasQ8WUA2
HPRD07606
IPIIPI00642862   IPI00513891   
Protein Interaction databases
DIP (DOE-UCLA)Q8WUA2
IntAct (EBI)Q8WUA2
FunCoupENSG00000131013
BioGRIDPPIL4
STRING (EMBL)PPIL4
ZODIACPPIL4
Ontologies - Pathways
QuickGOQ8WUA2
Ontology : AmiGOprotein peptidyl-prolyl isomerization  RNA binding  peptidyl-prolyl cis-trans isomerase activity  nucleoplasm  cytosol  protein folding  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  RNA binding  peptidyl-prolyl cis-trans isomerase activity  nucleoplasm  cytosol  protein folding  
NDEx NetworkPPIL4
Atlas of Cancer Signalling NetworkPPIL4
Wikipedia pathwaysPPIL4
Orthology - Evolution
OrthoDB85313
GeneTree (enSembl)ENSG00000131013
Phylogenetic Trees/Animal Genes : TreeFamPPIL4
HOVERGENQ8WUA2
HOGENOMQ8WUA2
Homologs : HomoloGenePPIL4
Homology/Alignments : Family Browser (UCSC)PPIL4
Gene fusions - Rearrangements
Fusion : QuiverPPIL4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPIL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPIL4
dbVarPPIL4
ClinVarPPIL4
1000_GenomesPPIL4 
Exome Variant ServerPPIL4
ExAC (Exome Aggregation Consortium)ENSG00000131013
GNOMAD BrowserENSG00000131013
Varsome BrowserPPIL4
Genetic variants : HAPMAP85313
Genomic Variants (DGV)PPIL4 [DGVbeta]
DECIPHERPPIL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPIL4 
Mutations
ICGC Data PortalPPIL4 
TCGA Data PortalPPIL4 
Broad Tumor PortalPPIL4
OASIS PortalPPIL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPIL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPIL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPIL4
DgiDB (Drug Gene Interaction Database)PPIL4
DoCM (Curated mutations)PPIL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPIL4 (select a term)
intoGenPPIL4
Cancer3DPPIL4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607609   
Orphanet
DisGeNETPPIL4
MedgenPPIL4
Genetic Testing Registry PPIL4
NextProtQ8WUA2 [Medical]
TSGene85313
GENETestsPPIL4
Target ValidationPPIL4
Huge Navigator PPIL4 [HugePedia]
snp3D : Map Gene to Disease85313
BioCentury BCIQPPIL4
ClinGenPPIL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85313
Chemical/Pharm GKB GenePA33590
Clinical trialPPIL4
Miscellaneous
canSAR (ICR)PPIL4 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPIL4
EVEXPPIL4
GoPubMedPPIL4
iHOPPPIL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:24:45 CEST 2018

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