Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PPIP5K1 (diphosphoinositol pentakisphosphate kinase 1)

Identity

Alias (NCBI)HISPPD2A
IP6K
IPS1
VIP1
hsVIP1
HGNC (Hugo) PPIP5K1
HGNC Alias symbKIAA0377
IPS1
VIP1
HGNC Previous nameHISPPD2A
HGNC Previous namehistidine acid phosphatase domain containing 2A
LocusID (NCBI) 9677
Atlas_Id 72136
Location 15q15.3  [Link to chromosome band 15q15]
Location_base_pair Starts at 43533462 and ends at 43584892 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPIP5K1   29023
Cards
Entrez_Gene (NCBI)PPIP5K1  9677  diphosphoinositol pentakisphosphate kinase 1
AliasesHISPPD2A; IP6K; IPS1; VIP1; 
hsVIP1
GeneCards (Weizmann)PPIP5K1
Ensembl hg19 (Hinxton)ENSG00000168781 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168781 [Gene_View]  ENSG00000168781 [Sequence]  chr15:43533462-43584892 [Contig_View]  PPIP5K1 [Vega]
ICGC DataPortalENSG00000168781
TCGA cBioPortalPPIP5K1
AceView (NCBI)PPIP5K1
Genatlas (Paris)PPIP5K1
WikiGenes9677
SOURCE (Princeton)PPIP5K1
Genetics Home Reference (NIH)PPIP5K1
Genomic and cartography
GoldenPath hg38 (UCSC)PPIP5K1  -     chr15:43533462-43584892 -  15q15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPIP5K1  -     15q15.3   [Description]    (hg19-Feb_2009)
GoldenPathPPIP5K1 - 15q15.3 [CytoView hg19]  PPIP5K1 - 15q15.3 [CytoView hg38]
ImmunoBaseENSG00000168781
genome Data Viewer NCBIPPIP5K1 [Mapview hg19]  
OMIM610979   
Gene and transcription
Genbank (Entrez)AB002375 AF502586 AF502587 AF502588 AF502589
RefSeq transcript (Entrez)NM_001024463 NM_001130858 NM_001130859 NM_001190214 NM_001354382 NM_001354383 NM_001354384 NM_001354385 NM_001354386 NM_001354387 NM_001354388 NM_001354389 NM_001354390 NM_001354391 NM_001354392 NM_001354393 NM_001354394 NM_001354395 NM_001354396 NM_001354397 NM_001354398 NM_001354399 NM_001354400 NM_001354401 NM_001354402 NM_014659
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPIP5K1
Alternative Splicing GalleryENSG00000168781
Gene ExpressionPPIP5K1 [ NCBI-GEO ]   PPIP5K1 [ EBI - ARRAY_EXPRESS ]   PPIP5K1 [ SEEK ]   PPIP5K1 [ MEM ]
Gene Expression Viewer (FireBrowse)PPIP5K1 [ Firebrowse - Broad ]
GenevisibleExpression of PPIP5K1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9677
GTEX Portal (Tissue expression)PPIP5K1
Human Protein AtlasENSG00000168781-PPIP5K1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PFW1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PFW1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PFW1
Splice isoforms : SwissVarQ6PFW1
Catalytic activity : Enzyme2.7.4.21 [ Enzyme-Expasy ]   2.7.4.212.7.4.21 [ IntEnz-EBI ]   2.7.4.21 [ BRENDA ]   2.7.4.21 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ6PFW1
Domaine pattern : Prosite (Expaxy)HIS_ACID_PHOSPHAT_1 (PS00616)   
Domains : Interpro (EBI)Acid_Pase_AS    His_Pase_clade-2    His_Pase_VIP1    His_PPase_superfam    VIP1_N   
Domain families : Pfam (Sanger)His_Phos_2 (PF00328)    PPIP5K2_N (PF18086)   
Domain families : Pfam (NCBI)pfam00328    pfam18086   
Conserved Domain (NCBI)PPIP5K1
DMDM Disease mutations9677
Blocks (Seattle)PPIP5K1
SuperfamilyQ6PFW1
Human Protein Atlas [tissue]ENSG00000168781-PPIP5K1 [tissue]
Peptide AtlasQ6PFW1
HPRD13798
IPIIPI00398511   IPI00877721   IPI00384259   IPI00657657   IPI00738361   IPI00005663   IPI00218030   IPI00829655   IPI00658157   IPI00657917   IPI00658005   IPI00887442   IPI00878424   IPI00894518   
Protein Interaction databases
DIP (DOE-UCLA)Q6PFW1
IntAct (EBI)Q6PFW1
FunCoupENSG00000168781
BioGRIDPPIP5K1
STRING (EMBL)PPIP5K1
ZODIACPPIP5K1
Ontologies - Pathways
QuickGOQ6PFW1
Ontology : AmiGOinositol-1,3,4,5,6-pentakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol heptakisphosphate kinase activity  inositol hexakisphosphate 5-kinase activity  ATP binding  cytosol  cytosol  cytosol  plasma membrane  inositol metabolic process  inositol metabolic process  phosphorylation  inositol phosphate biosynthetic process  diphosphoinositol-pentakisphosphate kinase activity  diphosphoinositol-pentakisphosphate kinase activity  inositol phosphate metabolic process  inositol hexakisphosphate 1-kinase activity  inositol hexakisphosphate 3-kinase activity  5-diphosphoinositol pentakisphosphate 3-kinase activity  
Ontology : EGO-EBIinositol-1,3,4,5,6-pentakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol heptakisphosphate kinase activity  inositol hexakisphosphate 5-kinase activity  ATP binding  cytosol  cytosol  cytosol  plasma membrane  inositol metabolic process  inositol metabolic process  phosphorylation  inositol phosphate biosynthetic process  diphosphoinositol-pentakisphosphate kinase activity  diphosphoinositol-pentakisphosphate kinase activity  inositol phosphate metabolic process  inositol hexakisphosphate 1-kinase activity  inositol hexakisphosphate 3-kinase activity  5-diphosphoinositol pentakisphosphate 3-kinase activity  
NDEx NetworkPPIP5K1
Atlas of Cancer Signalling NetworkPPIP5K1
Wikipedia pathwaysPPIP5K1
Orthology - Evolution
OrthoDB9677
GeneTree (enSembl)ENSG00000168781
Phylogenetic Trees/Animal Genes : TreeFamPPIP5K1
HOGENOMQ6PFW1
Homologs : HomoloGenePPIP5K1
Homology/Alignments : Family Browser (UCSC)PPIP5K1
Gene fusions - Rearrangements
Fusion : QuiverPPIP5K1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPIP5K1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPIP5K1
dbVarPPIP5K1
ClinVarPPIP5K1
1000_GenomesPPIP5K1 
Exome Variant ServerPPIP5K1
GNOMAD BrowserENSG00000168781
Varsome BrowserPPIP5K1
Genetic variants : HAPMAP9677
Genomic Variants (DGV)PPIP5K1 [DGVbeta]
DECIPHERPPIP5K1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPIP5K1 
Mutations
ICGC Data PortalPPIP5K1 
TCGA Data PortalPPIP5K1 
Broad Tumor PortalPPIP5K1
OASIS PortalPPIP5K1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPIP5K1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPPIP5K1
Mutations and Diseases : HGMDPPIP5K1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPIP5K1
DgiDB (Drug Gene Interaction Database)PPIP5K1
DoCM (Curated mutations)PPIP5K1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPIP5K1 (select a term)
intoGenPPIP5K1
Cancer3DPPIP5K1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610979   
Orphanet
DisGeNETPPIP5K1
MedgenPPIP5K1
Genetic Testing Registry PPIP5K1
NextProtQ6PFW1 [Medical]
TSGene9677
GENETestsPPIP5K1
Target ValidationPPIP5K1
Huge Navigator PPIP5K1 [HugePedia]
snp3D : Map Gene to Disease9677
BioCentury BCIQPPIP5K1
ClinGenPPIP5K1
Clinical trials, drugs, therapy
Protein Interactions : CTD9677
Pharm GKB GenePA165479401
Clinical trialPPIP5K1
Miscellaneous
canSAR (ICR)PPIP5K1 (select the gene name)
HarmonizomePPIP5K1
DataMed IndexPPIP5K1
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPIP5K1
EVEXPPIP5K1
GoPubMedPPIP5K1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 16:23:47 CEST 2020

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