Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PPIP5K2 (diphosphoinositol pentakisphosphate kinase 2)

Identity

Alias_namesHISPPD1
histidine acid phosphatase domain containing 1
Alias_symbol (synonym)KIAA0433
VIP2
CFAP160
Other aliasIP7K2
HGNC (Hugo) PPIP5K2
LocusID (NCBI) 23262
Atlas_Id 72137
Location 5q21.1  [Link to chromosome band 5q21]
Location_base_pair Starts at 103120248 and ends at 103204911 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IFI35 (17q21.31) / PPIP5K2 (5q21.1)PPIP5K2 (5q21.1) / TMEM161B (5q14.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPIP5K2   29035
Cards
Entrez_Gene (NCBI)PPIP5K2  23262  diphosphoinositol pentakisphosphate kinase 2
AliasesCFAP160; HISPPD1; IP7K2; VIP2
GeneCards (Weizmann)PPIP5K2
Ensembl hg19 (Hinxton)ENSG00000145725 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145725 [Gene_View]  chr5:103120248-103204911 [Contig_View]  PPIP5K2 [Vega]
ICGC DataPortalENSG00000145725
TCGA cBioPortalPPIP5K2
AceView (NCBI)PPIP5K2
Genatlas (Paris)PPIP5K2
WikiGenes23262
SOURCE (Princeton)PPIP5K2
Genetics Home Reference (NIH)PPIP5K2
Genomic and cartography
GoldenPath hg38 (UCSC)PPIP5K2  -     chr5:103120248-103204911 +  5q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPIP5K2  -     5q21.1   [Description]    (hg19-Feb_2009)
EnsemblPPIP5K2 - 5q21.1 [CytoView hg19]  PPIP5K2 - 5q21.1 [CytoView hg38]
Mapping of homologs : NCBIPPIP5K2 [Mapview hg19]  PPIP5K2 [Mapview hg38]
OMIM611648   
Gene and transcription
Genbank (Entrez)AB007893 AK025159 AK027116 AK294787 BC024591
RefSeq transcript (Entrez)NM_001276277 NM_001281471 NM_001345871 NM_001345872 NM_001345873 NM_001345874 NM_001345875 NM_001345876 NM_001345877 NM_001345878 NM_015216
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPIP5K2
Cluster EST : UnigeneHs.212046 [ NCBI ]
CGAP (NCI)Hs.212046
Alternative Splicing GalleryENSG00000145725
Gene ExpressionPPIP5K2 [ NCBI-GEO ]   PPIP5K2 [ EBI - ARRAY_EXPRESS ]   PPIP5K2 [ SEEK ]   PPIP5K2 [ MEM ]
Gene Expression Viewer (FireBrowse)PPIP5K2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23262
GTEX Portal (Tissue expression)PPIP5K2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43314   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43314  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43314
Splice isoforms : SwissVarO43314
PhosPhoSitePlusO43314
Domaine pattern : Prosite (Expaxy)HIS_ACID_PHOSPHAT_1 (PS00616)   
Domains : Interpro (EBI)Acid_Pase_AS    His_Pase_clade-2    His_PPase_superfam   
Domain families : Pfam (Sanger)His_Phos_2 (PF00328)   
Domain families : Pfam (NCBI)pfam00328   
Conserved Domain (NCBI)PPIP5K2
DMDM Disease mutations23262
Blocks (Seattle)PPIP5K2
PDB (SRS)3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
PDB (PDBSum)3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
PDB (IMB)3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
PDB (RSDB)3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
Structural Biology KnowledgeBase3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
SCOP (Structural Classification of Proteins)3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
CATH (Classification of proteins structures)3T54    3T7A    3T99    3T9A    3T9B    3T9C    3T9D    3T9E    3T9F    4HN2    4NZM    4NZN    4NZO    4Q4C    4Q4D    5BYA    5BYB    5DGH    5DGI   
SuperfamilyO43314
Human Protein AtlasENSG00000145725
Peptide AtlasO43314
HPRD13802
IPIIPI00784254   IPI00178375   IPI00908639   IPI00967255   IPI00967579   IPI00966926   IPI00966618   IPI00967317   IPI00966957   
Protein Interaction databases
DIP (DOE-UCLA)O43314
IntAct (EBI)O43314
FunCoupENSG00000145725
BioGRIDPPIP5K2
STRING (EMBL)PPIP5K2
ZODIACPPIP5K2
Ontologies - Pathways
QuickGOO43314
Ontology : AmiGOinositol-1,3,4,5,6-pentakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol heptakisphosphate kinase activity  inositol heptakisphosphate kinase activity  inositol hexakisphosphate 5-kinase activity  acid phosphatase activity  ATP binding  cytosol  cytosol  cytosol  inositol metabolic process  inositol metabolic process  phosphorylation  dephosphorylation  inositol phosphate biosynthetic process  diphosphoinositol-pentakisphosphate kinase activity  diphosphoinositol-pentakisphosphate kinase activity  inositol phosphate metabolic process  inositol hexakisphosphate 1-kinase activity  inositol hexakisphosphate 3-kinase activity  
Ontology : EGO-EBIinositol-1,3,4,5,6-pentakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol hexakisphosphate kinase activity  inositol heptakisphosphate kinase activity  inositol heptakisphosphate kinase activity  inositol hexakisphosphate 5-kinase activity  acid phosphatase activity  ATP binding  cytosol  cytosol  cytosol  inositol metabolic process  inositol metabolic process  phosphorylation  dephosphorylation  inositol phosphate biosynthetic process  diphosphoinositol-pentakisphosphate kinase activity  diphosphoinositol-pentakisphosphate kinase activity  inositol phosphate metabolic process  inositol hexakisphosphate 1-kinase activity  inositol hexakisphosphate 3-kinase activity  
NDEx NetworkPPIP5K2
Atlas of Cancer Signalling NetworkPPIP5K2
Wikipedia pathwaysPPIP5K2
Orthology - Evolution
OrthoDB23262
GeneTree (enSembl)ENSG00000145725
Phylogenetic Trees/Animal Genes : TreeFamPPIP5K2
HOVERGENO43314
HOGENOMO43314
Homologs : HomoloGenePPIP5K2
Homology/Alignments : Family Browser (UCSC)PPIP5K2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPIP5K2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPIP5K2
dbVarPPIP5K2
ClinVarPPIP5K2
1000_GenomesPPIP5K2 
Exome Variant ServerPPIP5K2
ExAC (Exome Aggregation Consortium)PPIP5K2 (select the gene name)
Genetic variants : HAPMAP23262
Genomic Variants (DGV)PPIP5K2 [DGVbeta]
DECIPHERPPIP5K2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPIP5K2 
Mutations
ICGC Data PortalPPIP5K2 
TCGA Data PortalPPIP5K2 
Broad Tumor PortalPPIP5K2
OASIS PortalPPIP5K2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPIP5K2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPIP5K2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPIP5K2
DgiDB (Drug Gene Interaction Database)PPIP5K2
DoCM (Curated mutations)PPIP5K2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPIP5K2 (select a term)
intoGenPPIP5K2
Cancer3DPPIP5K2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611648   
Orphanet
MedgenPPIP5K2
Genetic Testing Registry PPIP5K2
NextProtO43314 [Medical]
TSGene23262
GENETestsPPIP5K2
Target ValidationPPIP5K2
Huge Navigator PPIP5K2 [HugePedia]
snp3D : Map Gene to Disease23262
BioCentury BCIQPPIP5K2
ClinGenPPIP5K2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23262
Chemical/Pharm GKB GenePA165660454
Clinical trialPPIP5K2
Miscellaneous
canSAR (ICR)PPIP5K2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPIP5K2
EVEXPPIP5K2
GoPubMedPPIP5K2
iHOPPPIP5K2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:37:05 CEST 2017

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