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PPM1M (protein phosphatase, Mg2+/Mn2+ dependent 1M)

Identity

Alias_namesprotein phosphatase 1M (PP2C domain containing)
protein phosphatase, Mg2+/Mn2+ dependent, 1M
Alias_symbol (synonym)PP2Ceta
FLJ32332
Other aliasPP2C-eta
PP2CE
HGNC (Hugo) PPM1M
LocusID (NCBI) 132160
Atlas_Id 72139
Location 3p21.2  [Link to chromosome band 3p21]
Location_base_pair Starts at 52246170 and ends at 52250599 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD74 (5q32) / PPM1M (3p21.2)DDB1 (11q12.2) / PPM1M (3p21.2)PPM1M (3p21.2) / PPM1M (3p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPM1M   26506
Cards
Entrez_Gene (NCBI)PPM1M  132160  protein phosphatase, Mg2+/Mn2+ dependent 1M
AliasesPP2C-eta; PP2CE; PP2Ceta
GeneCards (Weizmann)PPM1M
Ensembl hg19 (Hinxton)ENSG00000164088 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164088 [Gene_View]  chr3:52246170-52250599 [Contig_View]  PPM1M [Vega]
ICGC DataPortalENSG00000164088
TCGA cBioPortalPPM1M
AceView (NCBI)PPM1M
Genatlas (Paris)PPM1M
WikiGenes132160
SOURCE (Princeton)PPM1M
Genetics Home Reference (NIH)PPM1M
Genomic and cartography
GoldenPath hg38 (UCSC)PPM1M  -     chr3:52246170-52250599 +  3p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPM1M  -     3p21.2   [Description]    (hg19-Feb_2009)
EnsemblPPM1M - 3p21.2 [CytoView hg19]  PPM1M - 3p21.2 [CytoView hg38]
Mapping of homologs : NCBIPPM1M [Mapview hg19]  PPM1M [Mapview hg38]
OMIM608979   
Gene and transcription
Genbank (Entrez)AA829740 AB474372 AI141068 AK056894 AK096681
RefSeq transcript (Entrez)NM_001122870 NM_144641
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPM1M
Cluster EST : UnigeneHs.731914 [ NCBI ]
CGAP (NCI)Hs.731914
Alternative Splicing GalleryENSG00000164088
Gene ExpressionPPM1M [ NCBI-GEO ]   PPM1M [ EBI - ARRAY_EXPRESS ]   PPM1M [ SEEK ]   PPM1M [ MEM ]
Gene Expression Viewer (FireBrowse)PPM1M [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)132160
GTEX Portal (Tissue expression)PPM1M
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MI6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MI6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MI6
Splice isoforms : SwissVarQ96MI6
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ96MI6
Domaine pattern : Prosite (Expaxy)PPM_2 (PS51746)   
Domains : Interpro (EBI)PP2C    PPM-type_phosphatase_dom   
Domain families : Pfam (Sanger)PP2C (PF00481)   
Domain families : Pfam (NCBI)pfam00481   
Domain families : Smart (EMBL)PP2Cc (SM00332)  
Conserved Domain (NCBI)PPM1M
DMDM Disease mutations132160
Blocks (Seattle)PPM1M
SuperfamilyQ96MI6
Human Protein AtlasENSG00000164088
Peptide AtlasQ96MI6
HPRD12350
IPIIPI00942895   IPI00167493   IPI00398744   IPI00165163   IPI00065520   IPI00916580   IPI00917220   
Protein Interaction databases
DIP (DOE-UCLA)Q96MI6
IntAct (EBI)Q96MI6
FunCoupENSG00000164088
BioGRIDPPM1M
STRING (EMBL)PPM1M
ZODIACPPM1M
Ontologies - Pathways
QuickGOQ96MI6
Ontology : AmiGOnucleus  protein dephosphorylation  CTD phosphatase activity  manganese ion binding  
Ontology : EGO-EBInucleus  protein dephosphorylation  CTD phosphatase activity  manganese ion binding  
NDEx NetworkPPM1M
Atlas of Cancer Signalling NetworkPPM1M
Wikipedia pathwaysPPM1M
Orthology - Evolution
OrthoDB132160
GeneTree (enSembl)ENSG00000164088
Phylogenetic Trees/Animal Genes : TreeFamPPM1M
HOVERGENQ96MI6
HOGENOMQ96MI6
Homologs : HomoloGenePPM1M
Homology/Alignments : Family Browser (UCSC)PPM1M
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPM1M [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPM1M
dbVarPPM1M
ClinVarPPM1M
1000_GenomesPPM1M 
Exome Variant ServerPPM1M
ExAC (Exome Aggregation Consortium)PPM1M (select the gene name)
Genetic variants : HAPMAP132160
Genomic Variants (DGV)PPM1M [DGVbeta]
DECIPHERPPM1M [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPM1M 
Mutations
ICGC Data PortalPPM1M 
TCGA Data PortalPPM1M 
Broad Tumor PortalPPM1M
OASIS PortalPPM1M [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPM1M  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPM1M
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPM1M
DgiDB (Drug Gene Interaction Database)PPM1M
DoCM (Curated mutations)PPM1M (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPM1M (select a term)
intoGenPPM1M
Cancer3DPPM1M(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608979   
Orphanet
MedgenPPM1M
Genetic Testing Registry PPM1M
NextProtQ96MI6 [Medical]
TSGene132160
GENETestsPPM1M
Target ValidationPPM1M
Huge Navigator PPM1M [HugePedia]
snp3D : Map Gene to Disease132160
BioCentury BCIQPPM1M
ClinGenPPM1M
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD132160
Chemical/Pharm GKB GenePA142671151
Clinical trialPPM1M
Miscellaneous
canSAR (ICR)PPM1M (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPM1M
EVEXPPM1M
GoPubMedPPM1M
iHOPPPM1M
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:35:06 CEST 2017

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