Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11)

Identity

Alias_namesTCTE5
protein phosphatase 1
Alias_symbol (synonym)HCGV
Tctex5
HCG-V
CFAP255
Other aliasIPP3
TCTEX5
HGNC (Hugo) PPP1R11
LocusID (NCBI) 6992
Atlas_Id 46838
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 30067155 and ends at 30070331 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
JUP (17q21.2) / PPP1R11 (6p22.1)PPP1R11 (6p22.1) / PPP1R11 (6p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R11   9285
Cards
Entrez_Gene (NCBI)PPP1R11  6992  protein phosphatase 1 regulatory inhibitor subunit 11
AliasesCFAP255; HCG-V; HCGV; IPP3; 
TCTE5; TCTEX5
GeneCards (Weizmann)PPP1R11
Ensembl hg19 (Hinxton)ENSG00000204619 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204619 [Gene_View]  ENSG00000204619 [Sequence]  chr6:30067155-30070331 [Contig_View]  PPP1R11 [Vega]
ICGC DataPortalENSG00000204619
TCGA cBioPortalPPP1R11
AceView (NCBI)PPP1R11
Genatlas (Paris)PPP1R11
WikiGenes6992
SOURCE (Princeton)PPP1R11
Genetics Home Reference (NIH)PPP1R11
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R11  -     chr6:30067155-30070331 +  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R11  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblPPP1R11 - 6p22.1 [CytoView hg19]  PPP1R11 - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIPPP1R11 [Mapview hg19]  PPP1R11 [Mapview hg38]
OMIM606670   
Gene and transcription
Genbank (Entrez)AF070599 AK310593 AK313175 BC003144 BC102010
RefSeq transcript (Entrez)NM_021959 NM_170781
RefSeq genomic (Entrez)NC_000006 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)PPP1R11
Cluster EST : UnigeneHs.82887 [ NCBI ]
CGAP (NCI)Hs.82887
Alternative Splicing GalleryENSG00000204619
Gene ExpressionPPP1R11 [ NCBI-GEO ]   PPP1R11 [ EBI - ARRAY_EXPRESS ]   PPP1R11 [ SEEK ]   PPP1R11 [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6992
GTEX Portal (Tissue expression)PPP1R11
Human Protein AtlasENSG00000204619-PPP1R11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60927   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60927  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60927
Splice isoforms : SwissVarO60927
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusO60927
Domains : Interpro (EBI)PPI_Ypi1   
Domain families : Pfam (Sanger)PPI_Ypi1 (PF07491)   
Domain families : Pfam (NCBI)pfam07491   
Conserved Domain (NCBI)PPP1R11
DMDM Disease mutations6992
Blocks (Seattle)PPP1R11
SuperfamilyO60927
Human Protein Atlas [tissue]ENSG00000204619-PPP1R11 [tissue]
Peptide AtlasO60927
HPRD09449
IPIIPI00030355   IPI00645264   
Protein Interaction databases
DIP (DOE-UCLA)O60927
IntAct (EBI)O60927
FunCoupENSG00000204619
BioGRIDPPP1R11
STRING (EMBL)PPP1R11
ZODIACPPP1R11
Ontologies - Pathways
QuickGOO60927
Ontology : AmiGOprotein phosphatase type 1 complex  protein serine/threonine phosphatase inhibitor activity  protein binding  nucleus  cytoplasm  ubiquitin-dependent protein catabolic process  protein phosphatase 1 binding  protein ubiquitination  negative regulation of phosphoprotein phosphatase activity  negative regulation of protein dephosphorylation  negative regulation of cytokine secretion  defense response to Gram-positive bacterium  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein phosphatase type 1 complex  protein serine/threonine phosphatase inhibitor activity  protein binding  nucleus  cytoplasm  ubiquitin-dependent protein catabolic process  protein phosphatase 1 binding  protein ubiquitination  negative regulation of phosphoprotein phosphatase activity  negative regulation of protein dephosphorylation  negative regulation of cytokine secretion  defense response to Gram-positive bacterium  ubiquitin protein ligase activity  
NDEx NetworkPPP1R11
Atlas of Cancer Signalling NetworkPPP1R11
Wikipedia pathwaysPPP1R11
Orthology - Evolution
OrthoDB6992
GeneTree (enSembl)ENSG00000204619
Phylogenetic Trees/Animal Genes : TreeFamPPP1R11
HOVERGENO60927
HOGENOMO60927
Homologs : HomoloGenePPP1R11
Homology/Alignments : Family Browser (UCSC)PPP1R11
Gene fusions - Rearrangements
Fusion : QuiverPPP1R11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R11
dbVarPPP1R11
ClinVarPPP1R11
1000_GenomesPPP1R11 
Exome Variant ServerPPP1R11
ExAC (Exome Aggregation Consortium)ENSG00000204619
GNOMAD BrowserENSG00000204619
Varsome BrowserPPP1R11
Genetic variants : HAPMAP6992
Genomic Variants (DGV)PPP1R11 [DGVbeta]
DECIPHERPPP1R11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R11 
Mutations
ICGC Data PortalPPP1R11 
TCGA Data PortalPPP1R11 
Broad Tumor PortalPPP1R11
OASIS PortalPPP1R11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R11
DgiDB (Drug Gene Interaction Database)PPP1R11
DoCM (Curated mutations)PPP1R11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R11 (select a term)
intoGenPPP1R11
Cancer3DPPP1R11(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606670   
Orphanet
DisGeNETPPP1R11
MedgenPPP1R11
Genetic Testing Registry PPP1R11
NextProtO60927 [Medical]
TSGene6992
GENETestsPPP1R11
Target ValidationPPP1R11
Huge Navigator PPP1R11 [HugePedia]
snp3D : Map Gene to Disease6992
BioCentury BCIQPPP1R11
ClinGenPPP1R11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6992
Chemical/Pharm GKB GenePA33614
Clinical trialPPP1R11
Miscellaneous
canSAR (ICR)PPP1R11 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R11
EVEXPPP1R11
GoPubMedPPP1R11
iHOPPPP1R11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:31:39 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.